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With excerpts from international specialists in the field of neurobiology, this book presents state of the art research on the neurobiological aspects of depression. It discusses opioid and endocannabinoid systems and depression and explores other sources for depression provided by research in biochemistry, molecular biology, and genomics. Topics covered include genetic factors of depression; monoaminergic pathways and depression; serotonergic pathways and depression; melantonergic system, chronobiological rhythms, and depression; the significance of tachykinin mechanisms in depression; and the melatonergic system, chronobiological rhythms, and depression. This book serves as a reference for researchers in neuroscience and related fields, as well as graduate students.