Novel Aspects of Pain Management: Opioids and Beyond

by Editor: Jana Sawynok (Dalhousie Univ., Nova Scotia, Canada); Editor: Alan Cowan (Temple Univ., Philadelphia, Pennsylvania)

• ISBN13: 9780471180173
• ISBN10: 0471180173
• Format: Hardcover
• Copyright: 1999-08-01
• Publisher: Wiley-Liss

Summary

Of related interest . . . Neuronal Nicotinic Receptors Pharmacology and Therapeutic Opportunities Edited by Stephen P. Arneric and Jorge D. Brioni Providing a comprehensive review of nicotinic receptors, this reference examines all aspects-from the molecular level to clinical applications. The editors cover the emerging molecular biological advances in the cloning of nAChRs, as well as the localization and regulation of these receptors, and the role these receptors have in central nervous system (CNS) disorder functions. Additionally, examined areas include in vivo pharmacology, and the therapeutic opportunities existing for agents that selectively interact with these receptors to treat CNS disorders. 1999 (0-471-24743-X) 440 pp. Purinergic Approaches in Experimental Therapeutics Edited by Kenneth A. Jacobson and Michael F. Jarvis Purinergic receptors are a type of neuroreceptor that has been found to have unique therapeutic potential as a chemical compound in the treatment of many neurological disorders such as Alzheimer's disease, chronic pain, Parkinson's disease, stroke, thrombosis, bladder function, stress, and cancer. This book covers the molecular pharmacology, medicinal chemistry, and experimental therapeutics of purinergic compounds. 1997 (0-471-14071-6) 600 pp.

Table of Contents

Preface	vii	(2)
Contributors	ix
1 NEUROPHYSIOLOGY OF ACUTE AND CHRONIC PAIN	1	(20)
Anthony Dickenson
Alison Reeve
2 ANIMAL MODELS OF PAIN	21	(28)
Alan Cowan
3 RECENT ADVANCES IN THE PHARMACOLOGY OF OPIOIDS	49	(24)
Michael H. Ossipov
Josephine Lai
T. Philip Malan, Jr.
Frank Porreca
4 SOME NEW INSIGHTS INTO THE PHARMACOLOGY OF NONSTEROIDAL ANTI-INFLAMMATORY DRUGS	73	(22)
Keith McCormack
5 PERIPHERALLY ACTING ANALGESIC AGENTS	95	(22)
Humphrey P. Rang
Stuart J. Bevan
Martin N. Perkins
6 VANILLOIDS AS ANALGESICS	117	(18)
Andy Dray
7 NEUROKININ ANTAGONISTS	135	(22)
Nadia M. J. Rupniak
Raymond G. Hill
8 EXCITATORY AMINO ACID ANTAGONISTS: POTENTIAL ANALGESICS FOR PERSISTENT PAIN	157	(22)
Terence J. Coderre
9 ALPHA-2 ADRENERGIC AGONISTS AS ANALGESICS	179	(24)
Tony L. Yaksh
10 SEROTONIN AND ITS RECEPTORS IN PAIN CONTROL	203	(26)
Michel Hamon
Sylvie Bourgoin
11 PURINES: POTENTIAL FOR DEVELOPMENT AS ANALGESIC AGENTS	229	(20)
Jana Sawynok
Anthony Poon
12 (Gamma)-AMINOBUTYRIC ACID AND PAIN	249	(16)
Norman G. Bowery
Marzia Malcangio
13 CHOLINERGIC AGONISTS AS ANALGESICS	265	(22)
Edgar T. Iwamoto
14 DOPAMINERGIC DRUGS AS ANALGESICS	287	(16)
Keith B. J. Franklin
15 TRICYCLIC AND OTHER ANTIDEPRESSANTS AS ANALGESICS	303	(18)
A. Eschalier
D. Ardid
C. Dubray
16 VOLTAGE-GATED ION CHANNEL MODULATORS	321	(24)
John C. Hunter
17 SPINAL DRUG INTERACTIONS	345	(18)
James C. Eisenach
G. F. Gebhart
Index	363