CART

(0) items

The Organic Chem Lab Survival Manual: A Student's Guide to Techniques,9781118083390
This item qualifies for
FREE SHIPPING!

FREE SHIPPING OVER $59!

Your order must be $59 or more, you must select US Postal Service Shipping as your shipping preference, and the "Group my items into as few shipments as possible" option when you place your order.

Bulk sales, PO's, Marketplace Items, eBooks, Apparel, and DVDs not included.

The Organic Chem Lab Survival Manual: A Student's Guide to Techniques

by
Edition:
9th
ISBN13:

9781118083390

ISBN10:
1118083393
Format:
Paperback
Pub. Date:
10/16/2012
Publisher(s):
John Wiley & Sons Inc
List Price: $86.65

Rent Textbook

(Recommended)
 
Term
Due
Price
$34.66

Buy Used Textbook

Usually Ships in 2-3 Business Days
U9781118083390
$60.66

Buy New Textbook

Currently Available, Usually Ships in 24-48 Hours
N9781118083390
$83.32

eTextbook


 
Duration
Price
$45.90
More New and Used
from Private Sellers
Starting at $57.11
See Prices

Questions About This Book?

Why should I rent this book?
Renting is easy, fast, and cheap! Renting from eCampus.com can save you hundreds of dollars compared to the cost of new or used books each semester. At the end of the semester, simply ship the book back to us with a free UPS shipping label! No need to worry about selling it back.
How do rental returns work?
Returning books is as easy as possible. As your rental due date approaches, we will email you several courtesy reminders. When you are ready to return, you can print a free UPS shipping label from our website at any time. Then, just return the book to your UPS driver or any staffed UPS location. You can even use the same box we shipped it in!
What version or edition is this?
This is the 9th edition with a publication date of 10/16/2012.
What is included with this book?
  • The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any CDs, lab manuals, study guides, etc.
  • The Used copy of this book is not guaranteed to include any supplemental materials. Typically, only the book itself is included.
  • The Rental copy of this book is not guaranteed to include any supplemental materials. You may receive a brand new copy, but typically, only the book itself.

Summary

This book presents the basic techniques of the organic chemistry laboratory with an emphasis on doing the work correctly the first time. New to this edition are discussions on safety in the laboratory with new consideration of the addition of such technology as the iPad, Nook, Kindle, and even text messaging. Updated discussion is added on Microscale; a number of NMR spectra have been added, with basic interpretation and suggestions on presentation of the data; and lastly, presentation of a more modern outline of the instrumentation of HPLC is included.

Table of Contents

CHAPTER 1 SAFETY FIRST, LAST, AND ALWAYS 1

Accidents Will Not Happen 5

Disposing of Waste 5

Mixed Waste 7

Material Safety Data Sheet (MSDS) 8

Green Chemistry and Planning an Organic Synthesis 9

An iBag for Your iThing 10

Exercises 10

CHAPTER 2 KEEPING A NOTEBOOK 11

A Technique Experiment 12

Notebook Notes 13

A Synthesis Experiment 13

Notebook Notes 13

Calculation of Percent Yield (Not Yeild!) 23

Estimation Is Your Friend 25

The Acid Test 25

Notebook Mortal Sin 25

Exercises 26

CHAPTER 3 INTERPRETING A HANDBOOK 27

CRC Handbook 28

Entry: 1-Bromobutane 28

Entry: Benzoic Acid 29

Lange’s 31

Entry: 1-Bromobutane 31

Entry: Benzoic Acid 31

Merck Index 31

Entry: 1-Bromobutane 33

Entry: Benzoic Acid 34

There’s a CD 34

The Aldrich Catalog 35

Entry: 1-Bromobutane 35

Entry: Benzoic Acid 36

Not Clear–Clear? 36

Info on the Internet 37

Exercises 37

CHAPTER 4 JOINTWARE 38

Stoppers with Only One Number 39

Another Episode of Love of Laboratory 40

Hall of Blunders and Things Not Quite Right 42

Round-Bottom Flasks 42

Columns and Condensers 43

The Adapter with Lots of Names 43

Forgetting the Glass 45

Inserting Adapter Upside Down 45

Inserting Adapter Upside Down sans Glass 46

The O-Ring and Cap Branch Out 46

Greasing the Joints 46

To Grease or Not to Grease 47

Preparation of the Joints 47

Into the Grease Pit 47

Storing Stuff and Sticking Stoppers 48

Corking a Vessel 48

CHAPTER 5 MICROSCALE JOINTWARE 50

Microscale: A Few Words 51

Uh-Oh Rings 51

The O-Ring Cap Seal 51

Skinny Apparatus 51

Not-So-Skinny Apparatus 52

Sizing Up the Situation 52

Why I Don’t Really Know How Vacuum-Tight These Seals Are 54

The Comical Vial (That’s Conical!) 54

The Conical Vial as Vial 55

Packaging Oops 55

Tare to the Analytical Balance 55

The Electronic Analytical Balance 56

Heating These Vials 56

The Microscale Drying Tube 57

Gas Collection Apparatus 58

Generating the Gas 59

Isolating the Product 61

CHAPTER 6 OTHER INTERESTING EQUIPMENT 62

Funnels, and Beakers, and Flasks—Oh My! 63

The Flexible Double-Ended Stainless Steel Spatula 63

CHAPTER 7 PIPET TIPS 66

Pre-Preparing Pasteur Pipets 67

Calibration 68

Operation 68

Amelioration 68

Pipet Cutting 70

Pipet Filtering—Liquids 70

Pipet Filtering—Solids 71

CHAPTER 8 SYRINGES, NEEDLES, AND SEPTA 73

The Rubber Septum 75

CHAPTER 9 CLEAN AND DRY 77

Drying Your Glassware When You Don’t Need To 78

Drying Your Glassware When You Do Need To 79

CHAPTER 10 DRYING AGENTS 80

Typical Drying Agents 81

Using a Drying Agent 82

Following Directions and Losing Product Anyway 82

Drying Agents: Microscale 83

Drying in Stages: The Capacity and Efficiency of Drying Agents 83

Exercises 83

CHAPTER 11 ON PRODUCTS 84

Solid Product Problems 85

Liquid Product Problems 85

The Sample Vial 85

Hold It! Don’t Touch That Vial 86

CHAPTER 12 THE MELTING-POINT EXPERIMENT 87

Sample Preparation 88

Loading the Melting-Point Tube 89

Closing Off Melting-Point Tubes 90

Melting-Point Hints 90

The Mel-Temp Apparatus 91

Operation of the Mel-Temp Apparatus 92

The Fisher-Johns Apparatus 93

Operation of the Fisher-Johns Apparatus 94

The Thomas-Hoover Apparatus 95

Operation of the Thomas-Hoover Apparatus 97

Using the Thiele Tube 99

Cleaning the Tube 100

Getting the Sample Ready 101

Dunking the Melting-Point Tube 102

Heating the Sample 103

Exercises 103

CHAPTER 13 RECRYSTALLIZATION 104

Finding a Good Solvent 105

General Guidelines for a Recrystallization 106

My Product Disappeared 107

Gravity Filtration 107

The Buchner Funnel and Filter Flask 110

Just a Note 113

The Hirsch Funnel and Friends 113

Activated Charcoal 114

The Water Aspirator: A Vacuum Source 114

The Water Trap 115

Working with a Mixed-Solvent System—The Good Part 115

The Ethanol–Water System 116

A Mixed-Solvent System—The Bad Part 116

Salting Out 117

World-Famous Fan-Folded Fluted Paper 118

Exercises 119

CHAPTER 14 RECRYSTALLIZATION: MICROSCALE 120

Isolating the Crystals 121

Craig Tube Filtration 122

Centrifuging the Craig Tube 124

Getting the Crystals Out 125

CHAPTER 15 EXTRACTION AND WASHING 127

Never-Ever Land 128

Starting an Extraction 129

Dutch Uncle Advice 130

The Separatory Funnel 131

The Stopper 131

The Glass Stopcock 131

The Teflon Stopcock 132

How to Extract and Wash What 134

The Road to Recovery—Back-Extraction 135

A Sample Extraction 136

Performing an Extraction or Washing 137

Extraction Hints 139

Exercises 140

CHAPTER 16 EXTRACTION AND WASHING: MICROSCALE 141

Mixing 142

Separation: Removing the Bottom Layer 142

Separation: Removing the Top Layer 143

Separation: Removing Both Layers 144

CHAPTER 17 SOURCES OF HEAT 145

Boiling Stones 146

The Steam Bath 146

The Bunsen Burner 147

Burner Hints 149

The Heating Mantle 150

Proportional Heaters and Stepless Controllers 152

Exercise 153

CHAPTER 18 CLAMPS AND CLAMPING 154

Clamping a Distillation Setup 157

Clipping a Distillation Setup 161

CHAPTER 19 DISTILLATION 164

Distillation Notes 165

Class 1: Simple Distillation 166

Sources of Heat 166

The Three-Way Adapter 167

The Distilling Flask 167

The Thermometer Adapter 168

The Ubiquitous Clamp 168

The Thermometer 168

The Condenser 168

The Vacuum Adapter 168

The Receiving Flask 169

The Ice Bath 169

The Distillation Example 169

The Distillation Mistake 170

Class 2: Vacuum Distillation 170

Pressure Measurement 171

Manometer Hints 173

Leaks 173

Pressure and Temperature Corrections 173

Vacuum Distillation Notes 177

Class 3: Fractional Distillation 178

How This Works 178

Fractional Distillation Notes 180

Azeotropes 183

Class 4: Steam Distillation 183

External Steam Distillation 184

Internal Steam Distillation 185

Steam Distillation Notes 185

Simulated Bulb-to-Bulb Distillation: Fakelrohr 187

Exercises 189

CHAPTER 20 MICROSCALE DISTILLATION 190

Like the Big Guy 191

Class 1: Simple Distillation 191

Class 2: Vacuum Distillation 191

Class 3: Fractional Distillation 191

Class 4: Steam Distillation 191

Microscale Distillation II: The Hickman Still 192

The Hickman Still Setup 192

Hickman Still Heating 193

Recovering Your Product 193

A Port in a Storm 194

CHAPTER 21 THE ROTARY EVAPORATOR 195

Exercises 199

CHAPTER 22 REFLUX AND ADDITION 200

Standard Reflux 201

A Dry Reflux 202

Addition and Reflux 204

Funnel Fun 204

How to Set Up 205

Exercise 207

CHAPTER 23 REFLUX: MICROSCALE 208

Addition and Reflux: Microscale 209

CHAPTER 24 SUBLIMATION 211

CHAPTER 25 MICROSCALE BOILING POINT 214

Microscale Boiling Point 215

Ultramicroscale Boiling Point 216

CHAPTER 26 CHROMATOGRAPHY: SOME GENERALITIES 218

Adsorbents 219

Separation or Development 219

The Eluatropic Series 219

CHAPTER 27 THIN-LAYER CHROMATOGRAPHY: TLC 222

We Don’t Make Our Own TLC Plates Any More, But… 223

Pre-prepared TLC Plates 223

The Plate Spotter 223

Spotting the Plates 224

Developing a Plate 225

Visualization 227

Interpretation 228

Multiple Spotting 230

Cospotting 230

Other TLC Problems 231

Preparative TLC 232

Exercises 233

CHAPTER 28 WET-COLUMN CHROMATOGRAPHY 234

Preparing the Column 235

Compounds on the Column 237

Visualization and Collection 238

Wet-Column Chromatography: Microscale 239

Flash Chromatography 241

Microscale Flash Chromatography 241

Exercises 241

CHAPTER 29 REFRACTOMETRY 242

The Abbé Refractometer 243

Before Using the Abbé Refractometer: A Little Practice 245

Using the Abbé Refractometer 245

Refractometry Hints 247

CHAPTER 30 GAS CHROMATOGRAPHY 248

The Mobile Phase: Gas 249

GC Sample Preparation 250

GC Sample Introduction 250

Sample in the Column 252

Sample at the Detector 252

Electronic Interlude 254

Sample on the Computer 255

Parameters, Parameters 256

Gas Flow Rate 256

Temperature 256

Exercises 257

CHAPTER 31 HP LIQUID CHROMATOGRAPHY 258

The Mobile Phase: Liquid 259

A Bubble Trap 259

The Pump and Pulse Dampener Module 261

HPLC Sample Preparation 262

HPLC Sample Introduction 263

Sample in the Column 264

Sample at the Detector 265

Sample on the Computer 266

Parameters, Parameters 266

Eluent Flow Rate 266

Temperature 266

Eluent Composition 267

Exercises 267

CHAPTER 32 INFRARED SPECTROSCOPY (AND A BIT OF UV-VIS, TOO) 268

Molecules as Balls on Springs 269

Ah, Quantum Mechanics 270

The Dissonant Oscillator 271

But Wait! There’s More 271

More Complicated Molecules 272

Correlation Tables to the Rescue 272

Troughs and Reciprocal Centimeters 272

Some Functional Group Analysis 278

A Systematic Interpretation 278

Infrared Sample Preparation 281

Liquid Samples 281

Solid Samples 282

Running the Spectrum 287

The Perkin-Elmer 710B IR 289

Using the Perkin-Elmer 710B 290

The 100% Control: An Important Aside 291

Calibration of the Spectrum 293

IR Spectra: The Finishing Touches 294

Interpreting IR Spectra—Finishing Touches 295

The Fourier Transform Infrared (FTIR) 296

The Optical System 296

A Reflectance Attachment: Something to Think About 300

And UV-VIS Too! 300

Electrons Get to Jump 300

Instrument Configuration 301

Source 301

Sample (and Reference) Cells 302

Solvents 303

Exercises 303

CHAPTER 33 NUCLEAR MAGNETIC RESONANCE 304

Nuclei Have Spin, Too 305

The Magnetic Catch 305

Everybody Line Up, Flip, and Relax 306

A More Sensitive Census 306

The Chemical Shift 307

T for One and Two 307

Be It Better Resolved . . . 308

Incredibly Basic FT-NMR 308

NMR Sample Preparation 309

Some NMR Terms and Interpretations 312

The Chemical Shift and TMS Zero 312

Integration and Labeling 314

Threaded Interpretations: Spectrum #1 (t-butyl alcohol) 315

Threaded Interpretations: Spectrum #2 (Toluene) and Spectrum #3 (p-Dichlorobenzene) 315

Threaded Interpretations: Spectrum #4 (Ethylbenzene) and Spectrum #5 (A Double Resonance Experiment) 319

Use a Correlation Chart 320

Exercises 323

CHAPTER 34 THEORY OF DISTILLATION 324

Class 1: Simple Distillation 325

Clausius and Clapeyron 327

Class 3: Fractional Distillation 328

A Hint from Dalton 328

Dalton and Raoult 329

A Little Algebra 329

Clausius and Clapeyron Meet Dalton and Raoult 330

Dalton Again 331

What Does It All Mean? 332

Reality Intrudes I: Changing Composition 335

Reality Intrudes II: Nonequilibrium Conditions 336

Reality Intrudes III: Azeotropes 336

Other Deviations 338

Class 4: Steam Distillation 339

CHAPTER 35 THEORY OF EXTRACTION 342

INDEX 345



Please wait while the item is added to your cart...