Palladium-Catalyzed Coupling Reactions Practical Aspects and Future Developments

by Molná; r, Á; rpá; d

• ISBN13: 9783527332540
• ISBN10: 3527332545
• Edition: 1st
• Format: Hardcover
• Copyright: 2013-05-20
• Publisher: Wiley-VCH

Summary

This handbook and ready reference brings together all significant issues of practical importance in selected topics discussing recent
significant achievements for interested readers in one single volume. While covering homogeneous and heterogeneous catalysis, the text is unique in focusing on such important aspects as using different reaction media, microwave techniques or catalyst recycling. It also provides a comprehensive treatment of key issues of modern-day coupling reactions having emerged and matured in recent years and emphasizes those topics that show potential for future development, such as continuous flow systems, water as a reaction medium, and catalyst immobilization, among others.

With its inclusion of large-scale applications in the pharmaceutical industry, this will equally be of great interest to industrial chemists.

From the contents
* Palladium-Catalyzed Cross-Coupling Reactions - A General Introduction
* High-turnover Heterogeneous Palladium Catalysts in Coupling Reactions: the Case of Pd Loaded on Dealuminated Y Zeolites
Palladium-Catalyzed Coupling Reactions with Magnetically Separable Nanocatalysts
* The Use of Ordered Porous Solids as Support Materials in Palladium-Catalyzed Cross-Coupling Reactions
* Coupling Reactions Induced by Polymer-Supported Catalysts
* Coupling Reactions in Ionic Liquids
* Cross-Coupling Reactions in Aqueous Media
* Microwave-Assisted Synthesis in C-C and C-Heteroatom Coupling Reactions
* Catalyst Recycling in Palladium-Catalyzed Carbon-Carbon Coupling Reactions
* Nature of the True Catalytic Species in Carbon-Carbon Coupling Reactions with
* Heterogeneous Palladium Precatalysts
* Coupling Reactions in Continuous Flow Systems
* Large-Scale Applications of Palladium-Catalyzed Couplings in the Pharmaceutical Industry

Author Biography

?rp?d Moln?r is a Professor of Chemistry, Department of Organic Chemistry, University of Szeged (retired in 2008). He earned his C.Sc. and D.Sc. degrees from the Hungarian Academy of Sciences in 1979 and 1990, respectively. He carried out postdoctoral research with Professor Gerard V. Smith at the Southern Illinois University at Carbondale in 1982-1983. He worked with Nobel laureate George A. Olah in Loker Hydrocarbon Research Institute at the University of Southern California in Los Angeles in 1992-1994 (Moulten Distinguished Fellow), 2001 and 2006-2007. He authored about 220 publications including original research papers, reviews, book chapters, and books.

Table of Contents

General introduction to cover the most important C-C coupling reactions
High-turnover Pd catalysts
Coupling/recycling with magnetically separable catalysts
Heterogeneous Pd catalysts supported on ordered solids
The use of polymers for immobilization
Coupling/recycling in non-conventional media (ionic liquids, supercritical CO2)
Coupling/recycling in aqueous media
Recycling - general discussion and major achievements
Microwave-assisted synthesis in coupling reactions
Coupling reactions in continuous flow systems
Industrial applications