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Physiology Cases and Problems



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This is the 4th edition with a publication date of 8/24/2012.

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Physiology Cases and Problems includes a collection of carefully selected patient case studies covering the clinically relevant physiology topics that first and second year medical students need to know for physiology coursework and for USMLE Step 1. Both courses and board exams focus on clinical topics and their relationship to the underlying science. The cases cover clinically relevant topics in physiology by asking students to answer open-ended questions and solve questions. A companion to Dr. Costanzo's BRS Physiology book, this book is also intended as a complement to lectures, course syllabi, and comprehensive textbooks in physiology.

Table of Contents

Prefacep. vi
Acknowledgmentsp. vii
Cellular and Autonomic Physiologyp. 1
Permeability and Simple Diffusionp. 2
Osmolarity, Osmotic Pressure, and Osmosisp. 7
Nernst Equation and Equilibrium Potentialsp. 13
Primary Hypokalemic Periodic Paralysisp. 19
Epidural Anesthesia: Effect of Lidocaine on Nerve Action Potentialsp. 24
Multiple Sclerosis: Myelin and Conduction Velocityp. 28
Myasthenia Gravis: Neuromuscular Transmissionp. 32
Pheochromocytoma: Effects of Catecholaminesp. 36
Shy-Drager Syndrome: Central Autonomic Failurep. 42
Cardiovascular Physiologyp. 47
Essential Cardiovascular Calculationsp. 48
Ventricular Pressure-Volume Loopsp. 57
Responses to Changes in Posturep. 64
Cardiovascular Responses to Exercisep. 69
Renovascular Hypertension: The Renin-Angiotensin-Aldosterone Systemp. 74
Hypovolemic Shock: Regulation of Blood Pressurep. 79
Primary Pulmonary Hypertension: Right Ventricular Failurep. 86
Myocardial Infarction: Left Ventricular Failurep. 91
Ventricular Septal Defectp. 97
Aortic Stenosisp. 101
Atrioventricular Conduction Blockp. 105
Respiratory Physiologyp. 109
Essential Respiratory Calculations: Lung Volumes, Dead Space, and Alveolar Ventilationp. 110
Essential Respiratory Calculations: Gases and Gas Exchangep. 116
Ascent to High Altitudep. 122
Asthma: Obstructive Lung Diseasep. 128
Chronic Obstructive Pulmonary Diseasep. 139
Interstitial Fibrosis: Restrictive Lung Diseasep. 146
Carbon Monoxide Poisoningp. 153
Pneumothoraxp. 157
Renal and Acid-Base Physiologyp. 161
Essential Calculations in Renal Physiologyp. 162
Essential Calculations in Acid-Base Physiologyp. 169
Glucosuria: Diabetes Mellitusp. 175
Hyperaldosteronism: Conn's Syndromep. 181
Central Diabetes Insipidusp. 189
Syndrome of Inappropriate Antidiuretic Hormonep. 198
Generalized Edema: Nephrotic Syndromep. 202
Metabolic Acidosis: Diabetic Ketoacidosisp. 208
Metabolic Acidosis: Diarrheap. 215
Metabolic Acidosis: Methanol Poisoningp. 219
Metabolic Alkalosis: Vomitingp. 223
Respiratory Acidosis: Chronic Obstructive Pulmonary Diseasep. 230
Respiratory Alkalosis: Hysterical Hyperventilationp. 234
Chronic Renal Failurep. 238
Gastrointestinal Physiologyp. 243
Difficulty in Swallowing: Achalasiap. 244
Malabsorption of Carbohydrates: Lactose Intolerancep. 248
Peptic Ulcer Disease: Zollinger-Ellison Syndromep. 253
Peptic Ulcer Disease: Helicobacter pylori Infectionp. 259
Secretory Diarrhea: Escherichia coli Infectionp. 263
Bile Acid Deficiency: Ileal Resectionp. 267
Liver Failure and Hepatorenal Syndromep. 272
Endocrine and Reproductive Physiologyp. 279
Growth Hormone-Secreting Tumor: Acromegalyp. 280
Galactorrhea and Amenorrhea: Prolactinomap. 284
Hyperthyroidism: Graves' Diseasep. 288
Hypothyroidism: Autoimmune Thyroiditisp. 295
Adrenocortical Excess: Cushing's Syndromep. 299
Adrenocortical Insufficiency: Addison's Diseasep. 304
Congenital Adrenal Hyperplasia: 21ß-Hydroxylase Deficiencyp. 309
Primary Hyperparathyroidismp. 312
Humoral Hypercalcemia of Malignancyp. 316
Hyperglycemia: Type I Diabetes Mellitusp. 320
Primary Amenorrhea: Androgen Insensitivity Syndromep. 324
Male Hypogonadism: Kallmann's Syndromep. 329
Male Pseudohermaphroditism: 5¿-Reductase Deficiencyp. 332
p. 337
p. 339
p. 341
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