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From its first edition 30 years ago, Robert Julien'sA Primer of Drug Actionhas evolved side by side with the field it covers, capturing the current state of the science of psychopharmacology with each new edition. Furthering that tradition, the new edition takes its place as the definitive guide to the pharmacology of drugs that affect the mind and behavior as understood today. With over 40% new research citations, there is no clearer, more current presentation available on the mechanisms of drug action, etiologies of major psychological disorders, rationales for drug treatment, and the uses of psychopharmacology in patient care.
The Author Robert M. Julien, M.D., received his M.S. and Ph.D. in Pharmacology from the University of Washington and his Medical Degree from the University of California at Irvine. His many research articles focus on the psychopharmacology of sedative and antiepileptic drugs. Previously an Associate Professor of Pharmacology and Anesthesiology at the Oregon Health Sciences University, he currently practices anesthesiology in Portland, Oregon.
New Contributors Claire D. Advokat, professor of psychology at LSU, received her Ph.D. from Rutgers University. Her primary interest is in understanding the clinical effectiveness and the mechanism of action of drugs used in the treatment of mental illness, such as the antipsychotics, antidepressants, mood stabilizers, and anxiolytics.
Joseph Comaty, Adjunct Professor at LSU, received his Ph.D. in clinical psychology from Rosalind Franklin University of Science and Medicine. His primary area of research is clinical psychopharmacology. In particular, he is interested in the study of the clinical treatment for the major psychiatric disorders of schizophrenia, major depression, and bipolar disorder.
Table of Contents
Part I Introduction to Psychopharmacology: How Drugs Interact with the Body and the Brain 1. Pharmacokinetics: How Drugs Are Handled by the Body 2. Pharmacodynamics: How Drugs Act 3. The Neuron, Synaptic Transmission, and Neurotransmitters
Part II Drugs That Depress Brain Function: Sedative-Hypnotic Drugs 4. Ethyl Alcohol and the Inhalants of Abuse 5. Barbiturates, General Anesthetics, Gamma Hydroxybutyrate (GHB), and Antiepileptic Drugs 6. Benzodiazepines and Second-Generation Anxiolytics
Part III Drugs That Are Used to Treat Psychological Disorders: Psychotherapeutics 7. Antidepressant Drugs 8. Drugs Used to Treat Bipolar Disorder (Mood Stabilizers) 9. Antipsychotic Drugs 10. Child and Adolescent Psychopharmacology 11. Geriatric Psychopharmacology 12. Integration of Drugs and Psychological Therapies into a Treatment Plan
Part IV Drugs That Stimulate Brain Function: Psychostimulants 13. Cocaine, the Amphetamines, and Non-Amphetamine Behavioral Stimulants 14. Caffeine and Nicotine
Part V Analgesic Drugs and Psychedelics 15. Non-Narcotic Anti-Inflammatory Analgesics 16. Opiod Analgesics 17. Cannabinoid Agonists and Antagonists 18. Psychedelic Drugs
Part VI Special Topics in Psychopharmacology 19. Herbal Medicines Used in the Treatment of Psychological Disorders 20. Anabolic Steroids 21. Topics in Drug Use