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9780781735254

Principles and Practice of Radiation Oncology

by ; ; ;
  • ISBN13:

    9780781735254

  • ISBN10:

    0781735254

  • Edition: 4th
  • Format: Hardcover
  • Copyright: 2003-09-24
  • Publisher: LWW
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List Price: $299.00

Summary

The Fourth Edition of this landmark work features nine new chapters and has been thoroughly revised and updated to reflect contemporary findings. It is the only text that covers every important aspect of radiation oncology--from basic cancer biology, radiation biology, and radiation therapy physics to state-of-the-art treatment regimens for all cancer sites and tumor types and discussions of results.Principles and Practice of Radiation Oncology is designed to provide a better understanding of the natural history of cancer, the physical methods of radiation application, the effects of irradiation on normal tissues, and the most judicious ways in which radiation therapy can be employed in the treatment of cancer patients. This encyclopedic text places greater emphasis on the use of radiation oncology in palliative and supportive care, in addition to therapy.Included in the new edition: chapters on molecular biology and physiology, technology assessment and cost benefit, combined chemotherapy and irradiation in head and neck cancer, breast: stage Tis, pancreas, leukemias (adult and childhood), retinoblastoma, unusual tumors in childhood, and endovascular brachytherapy. This edition also features expanded coverage of new 3-D techniques and IMRT and a greater emphasis on pediatric concerns.

Table of Contents

Contributors xi
Preface xix
TNM Cancer Staging xxi
Acknowledgments xxiii
SECTION 1: OVERVIEW AND BASIC SCIENCE OF RADIATION ONCOLOGY
1 The Discipline of Radiation Oncology
1(95)
Edward C. Halperin, Rupert K. Schmidt-Ullrich, Carlos A. Perez, and Luther W. Brady
Part A: Cancer Biology
2 Biologic Basis of Radiation Therapy
96(41)
William H. McBride and H. Rodney Withers
3 Molecular Cancer and Radiation Biology
137(26)
Rupert K. Schmidt-Ullrich, Ross B. Mikkelsen, and Kristoffer Valerie
4 Molecular Pathophysiology of Tumors
163(17)
Rakesh K. Jain
Part B: Medical Radiation Physics
5 Principles of Radiologic Physics, Dosimetry, and Treatment Planning
180(39)
James A. Purdy
6 Photon External-Beam Dosimetry and Treatment Planning
219(33)
James A. Purdy and Eric E. Klein
7 Electron-Beam Therapy: Dosimetry, Planning, and Techniques
252(31)
Kenneth R. Hogstrom
8 Three-Dimensional Conformal Radiation Therapy: Physics, Treatment Planning, and Clinical Aspects
283(31)
James A. Purdy
9 Intensity-Modulated Radiation Treatment Planning, Quality Assurance, Delivery, and Clinical Application
314(23)
Radhe Mohan, Daniel Low, K.S. Clifford Chao, Qiuwen Wu, and Lei Dong
SECTION 2: TECHNIQUES, MODALITIES, AND MODIFIERS IN RADIATION ONCOLOGY
10 Altered Fractionation Schedules
337(20)
K. Kian Ang and Howard D. Thames
11 Late Effects of Cancer Treatment on Normal Tissues
357(34)
Louis S. Contine, Jacqueline P. Williams, Monica Morris, Philip Rubin, and Paul Okunieff
12 Methodology of Clinical Trials
391(9)
Shani B. Rudoler, Kathryn Winter, and Walter J. Curran, Jr.
13 Magna-Field Irradiation
400(10)
Hsiu-San Lin and Robert E. Drzymala
14 Stereotactic Irradiation
410(18)
Annie W. Chan, Robert M. Cardinale, and Jay S. Loeffler
15 Intraoperative Radiation Therapy
428(29)
Felipe A. Calvo, Rosa M. Meirmo, Leonard L. Gunderson, and Christopher G. Willett
16 Particle Beam Radiotherapy: Clinical Perspective
457(15)
George E. Laramore and Mark H. Phillips
17 Physics and Biology of Brachytherapy
472(66)
Jeffrey Williamson and David J. Brenner
18 Clinical Applications of Brachytherapy I. LDR and PDR
538(66)
Carlos A. Perez, Robert Zwicker, and Jeffrey Williamson
19 Physics and Dosimetry of High-Dose-Rate Brachytherapy
604(15)
Colin G. Orton and Gary A. Ezzell
20 Clinical Aspects of High-Dose-Rate Brachytherapy
619(17)
Subir Nag
21 Nonsealed Radionuclide Therapy
636(17)
Carlos A. Perez, Perry W. Grigsby, and Wade Thorstad
22 Radioimmunoglobulins in Cancer Therapy
653(10)
Reiner Class, Curtis T. Miyamoto, and Luther W. Brady
23 Radiation Response Modulation
663(36)
Part A: Chemical Sensitizers and Protectors
Todd H. Wasserman and J. Donald Chapman
Part B: Biological Response Modifiers
Theodore D. Chung and Rupert K. Schmidt-Ullrich
24 Hyperthermia
699(37)
Ellen L. Jones, Thaddeus V. Samulski, Zeljko Vújaskovic, Leonard R. Prosnitz, and Mark W. Dewhirst
25 Basic Concepts of Chemotherapy and Irradiation Interaction
736(21)
Hak Choy, Rob MacRae, and Luka Milas
SECTION 3: CLINICAL RADIATION ONCOLOGY
Part A: Skin Cancer
26 Skin
757(19)
Merrill J. Solan and Luther W. Brady
Part B: AIDS-Related Malignancies
27 Malignant Neoplasms Associated with the Acquired Immunodeficiency Syndrome (AIDS)
776(15)
Bernadina R. Donahue and Jay S. Cooper
Part C: Central Nervous System Tumors
28 Brain, Brain Stem, and Cerebellum
791(48)
Loubna T. Scally, Chi Lin, Sushil Beriwal, Luther W. Brady
29 Pituitary
839(21)
Volker W. Stieber, Allan deGuzman, and Edward G. Shaw
30 Spinal Canal
860(16)
Jeff M. Michalski
31 Eye and Orbit
876(21)
Jorge E. Freire, Luther W. Brady, Jerry A. Shields, and Carol L. Shields
Part D: Head and Neck Tumors
32 Ear
897(8)
K.S. Clifford Chao and V. Rao Devinerai
33 The Role of Combined Radiation Therapy and Chemotherapy in the Management of Locally Advanced Squamous Carcinoma of the Head and Neck
905(13)
David M. Brizel
34 Nasopharynx
918(44)
K.S. Clifford Chao and Carlos A. Perez
35 Nasal Cavity and Paranasal Sinuses
962(14)
Jerry L. Barker, Jr., and K. Kian Ang
36 Salivary Glands
976(21)
Joseph R. Simpson
37 Oral Cavity
997(25)
Bateman Emami
38 Oropharynx (Tonsillar Fossa, Faucial Arch, and Base of Tongue)
1022(49)
Carlos A. Perez, K.S. Clifford Chao, Joseph R. Simpson, Rupert K. Schmidt-Ullrich
39 Hypopharynx
1071(23)
Bateman Emami and Rupert K Schmidt-Ullrich
40 Larynx
1094(23)
William M. Mendenhall, Russell W. Hinerman, Robert J. Amdur, Anthony A. Mancuso, Douglas B. Villaret, and K Thomas Robbins
41 Unusual Nonepithelial Tumors of the Head and Neck
1117(41)
Carlos A. Perez and K.S. Clifford Chao
42 Head and Neck: Management of the Neck
1158(21)
William M. Mendenhall, Robert J. Amdur, Russell W. Hinerman, Anthony A. Mancuso, Douglas B. Villaret, and K. Thomas Robbins
43 Thyroid
1179(22)
Perry W. Grigsby
Part E: Thoracic Tumors
44 Lung
1201(43)
Jeffrey Bradley, Ramaswamy Govindan, and Ritsuko Komaki
45 Mediastinum and Trachea
1244(38)
Tony Y. Eng, Todd J. Scarbrough, and Charles R. Thomas, Jr.
46 Esophagus
1282(23)
Albert S. DeNittis
47 Tumors of the Heart and Great Vessels
1305(10)
Mark A. Chidel and Roger M. Macklis
Part F: Breast Tumors
48 Breast: Stage Tis
1315(16)
David E. Wazer and Douglas W. Arthur
49 Breast: Stage T1 and T2 Tumors
1331(171)
Carlos A. Perez, Marie E. Taylor, Jeff Bradley, David Mansur, and Maria M. Sanchez Aragon
50 Breast: Locally Advanced (T3 and T4) and Recurrent Tumors
1502(52)
Marie E. Taylor, Carlos A. Perez, Joanne E. Mortimer, Seymour H. Levitt, Nantakan Ieumwananonthachai, and Sasha H. Wahab
Part G: Gastrointestinal Tumors
51 Stomach
1554(20)
Christopher G. Willett and Leonard L. Gunderson
52 Cancer of the Pancreas
1574(15)
Felipe A. Calvo, Juan C. Viera, Leonard L. Gunderson, and Christopher G. Willett
53 Liver and Hepatobiliary Tract
1589(18)
Skye H. Cheng and Andrew T. Huang
54 Colon and Rectum
1607(23)
Robert J. Myerson
55 Anal Canal
1630(19)
Bernard J. Cummings and James D. Brierley
Part H: Urinary Tract Tumors
56 Kidney, Renal Pelvis, and Ureter
1649(15)
Jeff M. Michalski
57 Bladder
1664(28)
Zbigniew Petrovich, John P. Stein, Gabor Jozsef, and Silvia C. Formenti
Part I: Male Genitourinary Tumors
58 Prostate Cancer
1692(71)
Michael J. Zelefsky, Richard K. Valicenti, Karyn Goodman, and Carlos A. Perez
59 Testis
1763(22)
Gerard C. Morton and Gillian M. Thomas
60 Penis and Male Urethra
1785(15)
David B. Mansur and K.S. C1if Jord Chao
Part J: Gynecologic Tumors
61 Uterine Cervix
1800(116)
Carlos A. Perez and Brian D. Kavanagh
62 Endometrium
1916(18)
John R. Glassburn, Luther W. Brady, and Perry W. Grigsby
63 Ovary
1934(24)
Michael D. Stambaugh
64 Fallopian Tube
1958(9)
Patrizia Guerrieri and Luther W. Brady
65 Vagina
1967(27)
Carlos A. Perez
66 Female Urethra
1994(9)
Jay Locke
67 Carcinoma of the Vulva
2003(20)
Gustavo S. Montana and Song K. Kang
Part K: Adrenal and Retroperitoneal Tumors
68 Retroperitoneum
2023(13)
Imran Zoberi and Todd H. Wasserman
69 Adrenal Gland
2036(7)
Luther W. Brady and Patrizia Guerrieri
Part L: Lymphoma and Hematologie Malignancies
70 Hodgkin's Disease
2043(21)
Richard T. Hoppe
71 Non-Hodgkins Lymphoma
2064(48)
Leonard R. Prosnitz and Peter M. Mauch
72 Cutaneous T-Cell Lymphoma
2112(13)
Sushil Beriwal, Luther W. Brady, and Eric C. Vonderheid
73 Leukemia
2125(32)
Christopher Coughlin, Rose Papac, and Kenneth B. Roberts
74 Myeloma and Plasmacytomas
2157(11)
Todd H. Wasserman
Part M: Sarcomas of Bone and Soft Tissue
75 Bone
2168(17)
Paolo Montemaggi, Luther W. Brady, and Stephen M. Horowitz
76 Soft Tissue Sarcomas (Excluding Retroperitoneum)
2185(21)
Cornelius J. McGinn
Part N: Pediatric Tumors
77 Central Nervous System Tumors in Children
2206(32)
Carolyn R. Freeman, Jean-Pierre Farmer, and Roger E. Taylor
78 Wilms' Tumor
2238(9)
John A. Kalapurakal and Patrick R.M. Thomas
79 Neuroblastoma
2247(14)
Jeff M. Michalski
80 Rhabdomyosarcoma
2261(16)
John C. Breneman and Sarah S. Donaldson
81 Ewing's Sarcoma
2277(8)
Robert B. Marcus, Jr.
82 Lymphomas in Children
2285(23)
Melissa Hudson, Barbara L. Asselin, Lynda R. Mandell, and Louis S. Constipe
83 Unusual Tumors in Childhood
2308(24)
Christian Carrie and Abraham Kuten
Part O: Benign Diseases
84 Radiation Treatment of Benign Disease
2332(20)
William Serber, Luther W. Brady, Mei Zhang, and Richard T. Hoppe
85 Endovascular Brachytherapy
2352(33)
Prabhakar Tripuraneni and Ian Crocker
SECTION 4: PALLIATIVE AND SUPPORTIVE CARE
86 Palliation of Brain and Spinal-Cord Metastases
2373(12)
A. Robert Kagan
87 Palliation of Bone Metastases
2385(20)
Vaneerat Ratanatharathorn, William E. Powers, and H. Thomas Temple
88 Palliation of Visceral Recurrences and Metastases
2405(7)
A. Robert Kagan
89 Pain Management
2412(14)
Nora A. Janjan
90 Supportive Care and Quality of Life in Radiation Oncology
2426(17)
Marvin Rotman, Darlene Johnson, and Todd H. Wasserman
SECTION 5: ECONOMICS, ETHICS, AND TECHNOLOGY ASSESSMENT
91 Technology Assessment, Cost Benefit, Outcome Research, and Evidence-Based Medicine
2443(18)
Carlos A. Perez, Ernest Franklin, Beverly Kobeissi, Edward C. Halperin, and Rupert K. Schmidt-Ullrich
92 Ethics, Professional Values, and Legal Considerations in Radiation Oncology
2461(10)
Brian D. Kavanagh, Laurie Lyckholm, and Jeremy Sugarman
Index 2471

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