9780125400794

Progress In Nucleic Acid Research And Molecular Biology

by
  • ISBN13:

    9780125400794

  • ISBN10:

    0125400799

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2005-06-20
  • Publisher: Elsevier Science
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Summary

Progress in Nucleic Acid Research and Molecular Biology provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology. It contains contributions from leaders in their fields and abundant references.

Table of Contents

SOME ARTICLES PLANNED FOR FUTURE VOLUMES ix
Genetic Switches During Bacteriophage λ Development 1(48)
Grzegorz Wegrzyn and Alicja Wegrzyn
I. Bacteriophage λ as a Model in Molecular Studies
2(1)
II. Developmental Pathways of Bacteriophage &lambda
3(3)
III. Genetic Switches: A Way to Regulate Bacteriophage λ Development
6(30)
IV. Concluding Remarks
36(1)
References
37(12)
Molecular Aspects of Meiotic Chromosome Synapsis and Recombination 49(84)
S. Anuradha and K. Muniyappa
I. General Introduction
50(1)
II. Meiosis
51(47)
III. G-quartets
98(10)
IV. Conclusions
108(1)
References
109(24)
Non-HKD Phospholipase D Enzymes: New Players in Phosphatidic Acid Signaling? 133(50)
Carlo Zambonelli and Mary F. Roberts
I. Introduction
133(1)
II. Phosphatidic Acid (PA)
134(13)
III. Phospholipase D (PLD) Enzymes
147(18)
IV. Dimetal Enzymes "Similar" to scPLD; Can They Do PLD Chemistry?
165(3)
V. Prospectus
168(2)
References
170(13)
Nucleotide Excision Repair 183(54)
Joyce T. Reardon and Aziz Sancar
I. Introduction
184(4)
II. Damage Recognition
188(6)
III. Excision Repair in Escherichia coli
194(5)
IV. Excision Repair in Humans
199(12)
V. Modulation of DNA Repair by Transcription
211(3)
VI. Repair of Chromatin
214(4)
VII. Repair of DNA Interstrand and DNA-Protein Cross-Links
218(1)
VIII. Concluding Comments
218(1)
References
219(18)
Signal Transduction Pathways in Cancer Development and as Targets for Cancer Prevention 237(62)
Ann M. Bode and Zigang Dong
I. Introduction
237(1)
II. Signals Involved in Neoplastic Cell Transformation and Carcinogenesis
238(9)
III. Carcinogen-Induced Signal Transduction
247(13)
IV. Chemoprevention and Signal Transduction Targets
260(15)
V. Conclusions/Summaries
275(1)
References
276(23)
ADAR Gene Family and A-to-I RNA Editing: Diverse Roles in Posttranscriptional Gene Regulation 299(40)
Louis Valente and Kazuko Nishikura
I. Historical Overview
300(3)
II. A Family of Editors
303(6)
III. Requirement of Double-Stranded RNA in the A-to-I RNA Editing Mechanism
309(13)
IV. Cellular Consequences
322(6)
V. Future Prospects
328(1)
References
329(10)
The Second Paradigm for Activation of Transcription 339(32)
S.R. Wigneshweraraj, P.C. Burrows, P. Bordes, J. Schumacher, M. Rappas, R.D. Finn, W.V. Cannon, X. Zhang, and M. Buck
I. Two Major Steps in Transcription Initiation
340(1)
II. The Bacterial Transcription Machinery
341(2)
III. The σ-54 Factor
343(8)
IV. The AAA Activator
351(5)
V. Determinants in Core RNAP
356(3)
VI. Toward a Detailed Mechanism for Activation
359(2)
References
361(10)
Families of Protein Phosphatase 1 Modulators Activated by Protein Kinases A and C: Focus on Brain 371(34)
Qing-Rong Liu, Jian-Ping Gong, and George R. Uhl
I. Introduction
372(1)
II. A Family of Protein Kinase A (PKA)-Activated PP1 Inhibitors
373(3)
III. A Family of Protein Kinase C (PKC)-Activated PP1 Inhibitors
376(5)
IV. Function of PKA- and PKC-Dependent PP1 Inhibitors
381(11)
V. Comparisons of the Families of PKA- and PKC-Dependent PP1 Inhibitors
392(3)
VI. Conclusions
395(1)
References
396(9)
Index 405

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