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9783527319145

Pseudomonas : Model Organism, Pathogen, Cell Factory

by
  • ISBN13:

    9783527319145

  • ISBN10:

    352731914X

  • Format: Hardcover
  • Copyright: 2008-05-01
  • Publisher: Blackwell Pub
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List Price: $299.95

Summary

Concise and up-to-date, this handy guide fills a gap in the literature by providing the essential knowledge for everyone with an interest in the topic. The result is a comprehensive overview of the most important model organism in applied microbiology that covers basic biology, pathology and biotechnological applications.

Author Biography

Bernd Rehm is Chair of Microbiology at Massey University in New Zealand. Having obtained his academic degrees at the Universities of Bochum and Münster (Germany), he spent two years at the University of British Columbia (Canada), before setting us his own laboratory at the University of Münster. In 2003, he took up his present appointment at Massey University. Professor Rehm is a member of the editorial board for several scientific journals and is the co-organizer of the international symposium on biological polyester.

Table of Contents

Preface
List of Contributors
Comparative Genomics of Pseudomonas
Introduction
Pan/Core Genome of Pseudomonas
Phylogeny of Pseudomonas
Blast Atlas of Pseudomonas Genomes
Functional Categories
Codon Usage and Expression
Future Outlook
References
Clinical Relevance of Pseudomonas aeruginosa: A Master of Adaptation and Survival Strategies
Introduction
CF
Survival of P. aeruginosa by Adaptation to the Inflammatory Defense System
Conductive and the Respiratory Zones of the Lungs
Survival of P. aeruginosa by Adaptation to the Respiratory Zone of the Lungs
Survival of P. aeruginosa by Adaptation to the Conductive Zone of the Lungs
Survival of P. aeruginosa by Adaptation to the Antibiotic Therapy
Evolutionary Implications of the Adaptability of P. aeruginosa
References
Adherence of Pseudomonas aeruginosa
Introduction
What is Adherence?
Role of Adherence in Infection
How is Bacterial Adherence Associated with Virulence?
P. aeruginosa Adhesins
Surface Receptor Requirements of the Pilus Adhesin
How Does PilA Mediate Attachment to Human Mucosal Surfaces?
X-ray Crystallographic Structural Studies of the Pilin Structural Protein
Structure of the Pilus Fiber
Structure of the Receptor-Binding Domain and Location on the Pilus
Structural Nature of the Receptor-Binding Domain
Twitching Motility
How Does the Pilus Attach to a Solid Surface?
The Monkey-Bar Swing Paradox
Molecular Basis for Receptor-binding Domain Interaction with Steel Surfaces
Pili as Nanowires for Redox Reactions
What is the Most Important Role of Adherence to P. aeruginosa
References
Flagella and Pili of Pseudomonas aeruginosa
Introduction
Flagellum of P. aeruginosa
Pili of P. aeruginosa
Conclusions
References
Pseudomonas Motility and Chemotaxis
Introduction
Chemotaxis Assay Methods
Ecological Aspects of Chemotaxis
Molecular Biology of Chemotaxis in Pseudomonas
Pseudomonas as Model Microorganisms for Chemotaxis Research
References
Iron Transport and Signaling in Pseudomonads
Introduction
Siderophores Used by Pseudomonads
Siderophore Synthesis
Ferri-Siderophore Transport
Regulation of Siderophore Synthesis and Transport
Introduction to Signaling
Concluding Remarks and Future Perspectives
References
Quorum Sensing in Pseudomonads (
Table of Contents provided by Publisher. All Rights Reserved.

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