CART

(0) items

Pulmonary Physiology

by
Edition:
5th
ISBN13:

9780071345439

ISBN10:
0071345434
Format:
Paperback
Pub. Date:
3/31/1999
Publisher(s):
McGraw-Hill Incorporated

Related Products


  • Pulmonary Physiology
    Pulmonary Physiology
  • Pulmonary Physiology 8/E
    Pulmonary Physiology 8/E
  • Pulmonary Physiology, Seventh Edition
    Pulmonary Physiology, Seventh Edition





Summary

Provides a solid background in the structure and function of the respiratory system which is essential for the understanding of clinical medicine. The book utilizes clear, simple illustrations to stress concepts rather than facts, which helps foster understanding rather than memorization. Each chapter clearly states the learning objectives, so users will know what they are expected to learn before reading a chapter, thereby encourage self-instruction. Lastly, study questions allow the reader to test their understanding of the key concepts presented, and an extensive listing of up-to-date references is included for further reading.

Table of Contents

Preface xiii
Function and Structure of the respiratory system
1(12)
Objectives
1(1)
Functions of the Respiratory System
2(2)
Gas Exchange
2(1)
Other Functions
2(2)
Structure of the Respiratory System
4(9)
The Alveolar-Capillary Unit
4(3)
The Airways
7(3)
The Muscles of Respiration and the Chest Wall
10(1)
The Central Nervous System and the Neural Pathways
11(2)
Mechanics of Breathing
13(42)
Objectives
13(1)
Generation of a Pressure Gradient Between Atmosphere and Alveoli
14(7)
Passive Expansion of Alveoli
14(1)
Negative Intrapleural Pressure
14(1)
The Muscles of Respiration
15(5)
Summary of the Events Occurring During the Course of a Breath
20(1)
Pressure-Volume Relationships in the Respiratory System
21(11)
Compliance of the Lung and the Chest Wall
23(3)
Elastic Recoil of the Lung
26(2)
Pulmonary Surfactant
28(3)
Alveolar Interdependence
31(1)
Interaction of Lung and Chest Wall: The Static Pressure-Volume Curve
32(2)
Airways Resistance
34(19)
Laminar, Turbulent, and Transitional Flow
35(3)
Distribution of Airways Resistance
38(1)
Control of Bronchial Smooth Muscle
38(1)
Lung Volume and Airways Resistance
39(1)
Dynamic Compression of Airways
40(3)
Assessment of Airways Resistance
43(7)
Dynamic Compliance
50(3)
The Work of Breathing
53(2)
Elastic Work
53(1)
Resistive Work
54(1)
Alveolar Ventilation
55(30)
Objectives
55(1)
The Lung Volumes
56(2)
The Standard Lung Volumes and Capacities
56(2)
Measurement of the Lung Volumes
58(8)
Spirometry
60(2)
Measurement of Lung Volumes Not Measurable with Spirometry
62(4)
Anatomic Dead Space and Alveolar Ventilation
66(2)
Measurement of Alveolar Ventilation
68(4)
Measurement of Anatomic Dead Space
68(1)
Physiologic Dead Space: The Bohr Equation
69(3)
Alveolar Ventilation and Alveolar Oxygen and Carbon Dioxide Levels
72(5)
Partial Pressures of Respiratory Gases
73(2)
Alveolar Ventilation and Carbon Dioxide
75(1)
Alveolar Ventilation and Oxygen
75(2)
Regional Distribution of Alveolar Ventilation
77(4)
Demonstration of Differences Between Dependent and Nondependent Regions
77(1)
Explanation for Differences in Regional Alveolar Ventilation
78(2)
Alterations of Distribution at Different Lung Volumes
80(1)
The Closing Volume
81(2)
The Effects of Aging
83(2)
Blood Flow To The Lung
85(28)
Objectives
85(1)
The Bronchial Circulation
86(2)
The Functional Anatomy of the Pulmonary Circulation
88(4)
Determination of Pulmonary Vascular Resistance
89(1)
Distribution of Pulmonary Vascular Resistance
90(1)
Consequences of Differences in Pressure Between the Systemic and Pulmonary Circulations
90(2)
Pulmonary Vascular Resistance
92(7)
The Concept of a Transmural Pressure Gradient
92(1)
Lung Volume and Pulmonary Vascular Resistance
92(3)
Recruitment and Distensibility
95(3)
Control of Pulmonary Vascular Smooth Muscle
98(1)
The Regional Distribution of Pulmonary Blood Flow: The Zones of the Lung
99(7)
Measurement of Total Pulmonary Blood Flow
100(2)
Determination of Regional Pulmonary Blood Flow
102(1)
The Regional Distribution of Pulmonary Blood Flow
102(2)
The Interaction of Gravity and Extravascular Pressure: The Zones of the Lung
104(2)
Hypoxic Pulmonary Vasoconstriction
106(1)
Mechanism of Hypoxic Pulmonary Vasoconstriction
106(1)
Physiologic Function of Hypoxic Pulmonary Vasoconstriction
107(1)
Pulmonary Edema
107(6)
The Factors Influencing Liquid Movement in the Pulmonary Capillaries
107(1)
Lymphatic Drainage of the Lung
108(1)
Conditions That May Lead to Pulmonary Edema
109(4)
Ventilation-Perfusion Relationships
113(18)
Objectives
113(1)
The Concept of Matching Ventilation and Perfusion
113(1)
Consequences of High and Low VA/QC
114(3)
Testing for Nonuniform Distribution of Inspired Gas and Pulmonary Blood Flow
117(9)
Testing for Nonuniform Distribution of Inspired Gas
117(3)
Testing for Nonuniform Distribution of Pulmonary Blood Flow
120(1)
Testing for Mismatched Ventilation and Perfusion
120(6)
Regional VA/QC Differences and Their Consequences in the Lung
126(5)
Regional Differences in the Ventilation-Perfusion Ratios in the Upright Lung
127(1)
The Consequences of Regional Ventilation-Perfusion Differences in the Normal Upright Lung
128(3)
Diffusion of Gases
131(12)
Objectives
131(1)
Fick's Law for Diffusion
132(2)
Limitations of Gas Transfer
134(2)
Diffusion Limitation
134(2)
Perfusion Limitation
136(1)
Diffusion of Oxygen
136(1)
Diffusion of Carbon Dioxide
137(2)
Measurement of Diffusing Capacity
139(4)
The Transport of Oxygen And Carbon Dioxide in The Blood
143(22)
Objectives
143(1)
Transport of Oxygen by the Blood
144(2)
Physically Dissolved
144(1)
Chemically Combined with Hemoglobin
145(1)
Chemical Reaction of Oxygen and Hemoglobin
146(1)
Hemoglobin and the Physiologic Implications of the Oxyhemoglobin Dissociation Curve
146(4)
The Oxyhemoglobin Dissociation Curve
146(4)
Influences on the Oxyhemoglobin Dissociation Curve
150(9)
Effects of pH and PCO2
150(1)
Effects of Temperature
151(1)
Effects of 2,3-BPG
151(1)
Physiologic Consequences of the Effects of Temperature, pH, PCO2, and 2,3-BPG
151(3)
Other Factors Affecting Oxygen Transport
154(5)
Transport of Carbon Dioxide by the Blood
159(2)
Physically Dissolved
159(1)
As Carbamino Compounds
160(1)
As Bicarbonate
160(1)
The Carbon Dioxide Dissociation Curve
161(1)
The Bohr and Haldane Effects Explained
161(4)
The Regulation of Acid-Base Status
165(24)
Objectives
165(1)
The Chemistry of Acids, Bases, and Buffers
166(2)
The Quantification of Acidity
166(1)
The Importance of Body pH Regulation
167(1)
Sources of Acids in the Body
168(1)
Buffer Systems of the Human Body
168(6)
Bicarbonate
170(2)
Phosphate
172(1)
Proteins
173(1)
Buffers of the Interstitial Fluid
174(1)
Bone
174(1)
Intracellular Buffering
174(1)
Acidosis and Alkalosis
174(4)
Respiratory Acidosis
174(2)
Respiratory Alkalosis
176(1)
Metabolic Acidosis
177(1)
Metabolic Alkalosis
178(1)
Respiratory and Renal Compensatory Mechanisms
178(3)
Respiratory Compensatory Mechanisms
178(1)
Renal Compensatory Mechanisms
179(2)
Summary of Renal and Respiratory Contributions to Acid-Base Balance
181(1)
Clinical Interpretation of Blood Gases and Acid-Base Status
181(2)
Base Excess
182(1)
Anion Gap
183(1)
The Causes of Hypoxia
183(6)
Hypoxic Hypoxia
184(2)
Hypoperfusion Hypoxia
186(1)
Histotoxic Hypoxia
187(1)
Other Causes of Hypoxia
187(1)
The Effects of Hypoxia
187(2)
The Control of Breathing
189(28)
Objectives
189(1)
The Generation of Spontaneous Rhythmicity
190(1)
The Medullary Respiratory Center
191(2)
The Dorsal Respiratory Group
191(2)
The Ventral Respiratory Group
193(1)
The ``Apneustic Center''
193(1)
The Pontine Respiratory Group
194(1)
Spinal Pathways
194(1)
Reflex Mechanisms of Respiratory Control
195(7)
Respiratory Reflexes Arising from Pulmonary Stretch Receptors
195(4)
Respiratory Reflexes Arising from Receptors in the Airways and the Lungs
199(1)
Respiratory Reflexes Arising from Pulmonary Vascular Receptors (J Receptors)
199(2)
Respiratory Reflexes Arising from the Cardiovascular System
201(1)
Respiratory Reflexes Arising from Muscles and Tendons
201(1)
Reflex Respiratory Responses to Pain
202(1)
Influences of Higher Centers
202(1)
The Response to Carbon Dioxide
202(7)
Peripheral Chemoreceptors
207(1)
Central Chemoreceptors
207(2)
The Response to Hydrogen Ions
209(1)
The Response to Hypoxia
210(2)
The Response to Exercise
212(5)
Nonrespiratory Functions of The Lung
217(14)
Objectives
217(1)
Pulmonary Defense Mechanisms
217(6)
Air-Conditioning
218(1)
Olfaction
218(1)
Filtration and Removal of Inspired Particles
218(5)
Nonrespiratory Functions of the Pulmonary Circulation
223(3)
Reservoir for the Left Ventricle
223(1)
The Pulmonary Circulation as a Filter
224(2)
Fluid Exchange and Drug Absorption
226(1)
Metabolic Functions of the Lung
226(5)
Metabolism of Vasoactive Substances
227(1)
Formation and Release of Chemical Substances for Local Use
228(1)
Formation and Release into the Blood of Substances Produced by Lung Cells
229(1)
Other Metabolic Functions
229(2)
The Respiratory System Under Stress
231(22)
Objectives
231(1)
Exercise and the Respiratory System
231(7)
Acute Effects
232(4)
Training Effects
236(2)
Altitude and Acclimatization
238(6)
Acute Effects
239(3)
Acclimatization
242(2)
Diving and the Respiratory System
244(9)
Physical Principles
244(1)
Effects of Immersion up to the Neck
245(1)
Breath-Hold Diving
246(1)
The Use of Underwater Breathing Apparatus
247(6)
STUDY QUESTIONS 253(22)
APPENDIX 275(4)
I. Symbols Used in Respiratory Physiology
275(1)
II. The Laws Governing the Behavior of Gases
275(1)
III. Frequently Used Equations
276(1)
IV. Pulmonary Function Test Decision Tree
277(1)
V. Table of Normal Respiratory and Circulatory Values
278(1)
Suggested Readings 279(14)
Index 293


Please wait while the item is added to your cart...