Rapid Eye Movement Sleep: Regulation and Function

by Edited by Birendra N. Mallick , S. R. Pandi-Perumal , Robert W. McCarley , Adrian R. Morrison

• ISBN13: 9780521116800
• ISBN10: 0521116805
• Format: Hardcover
• Copyright: 2011-08-22
• Publisher: Cambridge University Press

Summary

Spanning over half a century of investigation into Rapid Eye Movement (REM) sleep, this volume provides comprehensive coverage of a broad range of topics in REM sleep biology. World renowned researchers and experts are brought together to discuss past and current research and to set the foundation for future developments. Key topics are covered in six sections from fundamental topics (historical context and general biology) to cutting-edge research on neuronal regulation, neuroanatomy and neurochemistry, functional significance and disturbance in the REM sleep generating mechanism. A reference source for all aspects of REM sleep research, it also incorporates chapters on neural modelling, findings from non-human species and interactions between brain regions. This is an invaluable resource, essential reading for all involved in sleep research and clinical practice.

Table of Contents

REM Sleep as a Unique Arousal State - Historical Context:

The sleep-dream state - historic and philosophic perspectives

REM sleep and dreaming

REM sleep and dream sleep: are they identical? Exploring the conceptual developments in the Upanishads and the present knowledge based on neurobiology of sleep

The discovery of REM sleep: the death knell of the passive theory of sleep

REM sleep and dreaming: the nature of the relationship

General Biology:

The ontogeny and function(s) of REM sleep

Evolutionary perspectives on the function of REM sleep

A systems level approach to human REM sleep

REM sleep regulation: circadian, homeostatic and non-REM sleep-dependent determinants

Neuronal Regulation:

Understanding REM sleep: clues from brain lesion studies

Preoptic and basal forebrain modulation of REM sleep

Amygdalar regulation of REM sleep

Pontomedullary mediated REM sleep atonia

Phenomenology and function of myoclonic twitching in developing rats

Pontine-wave (P-wave) generator: a key player in REM sleep-dependent memory consolidation

Hippocampal theta rhythm of REM sleep

Respiration during REM sleep and its regulation

Modulation of REM sleep by non-REM sleep and waking areas in the brain

Neuroanatomy and Neurochemistry:

Aminergic influences in the regulation of basic REM sleep processes

REM sleep regulation by cholinergic neurons: highlights from 1999 to 2009

GABAergic modulation of REM sleep

Glutamatergic regulation of REM

The role of tuberomammillary nucleus histaminergic neurons, and of their receptors, in the regulation of sleep and waking

Hypocretinergic system: role in REM sleep regulation

Neuropeptides and REM sleep

Adenosine and glycine in REM sleep regulation

Changes in neurotransmitter levels in relation to REM sleep for its regulation

Pontine areas inhibiting REM sleep (PAIRS)

Neuronal models of REM sleep control: evolving concepts

REM Sleep: Functional Significance:

Significance of deprivation studies: does REM sleep propensity/debt increase with deprivation?

Modulation of body core temperature in NREM and REM sleep

Sleep-related hippocampal activation: implications for spatial memory consolidation

The role of REM sleep in memory consolidation, enhancement and integration

The role of REM sleep in emotional brain processing

REM sleep loss, oxidative damage and apoptosis

Role of REM sleep in maintaining neuronal excitability and its possible mechanism of action

Comparison of REM sleep deprivation methods: role of stress and validity of use

REM sleep in patients with depression

Proteins and neuropeptides in REM sleep regulation and function

Disturbance in REM Sleep Generating Mechanism:

Narcolepsy and REM sleep

REM sleep and dreams: relationship to anxiety, psychosomatic and behavioural disorders

REM sleep and emotion regulation

Neural modeling for cooperative/competitive regulation of REM sleep with NREM sleep and wakefulness

The selective mood regulatory theory of dreaming: an adaptive, assimilative and experimentally based theory of dreaming

Index

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