Substance P Receptors in the Nervous System

Neuropeptides are involved in virtually all aspects of neuroscience. The substance P receptor (SPR) is a G protein-coupled receptor that has long been believed to play a role in pain and inflammation. Recent studies indicate that SPR may be a key player in several human diseases, including depression and brain tumors. These recent findings have generated a keen interest in SPR as a target of drug development. Substance P Receptors in the Nervous System is the first of its kind to bring into focus these new breakthroughs. It synthesizes new research, techniques, theories, and future directions and provides an up-to-date account of advances in substance P receptor biology.