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9780323010054

Mosby's Pharmacology in Nursing

by
  • ISBN13:

    9780323010054

  • ISBN10:

    0323010059

  • Edition: 21st
  • Format: Hardcover
  • Copyright: 2000-10-01
  • Publisher: Elsevier Science Health Science div
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List Price: $65.95

Summary

Mosby's Pharmacology in Nursing is the classic pharmacology text now made even better. Known for its comprehensive coverage of nursing pharmacology, the 22nd edition retains the strong nursing focus but now features a new student-friendly look in a case-study format to help students apply pharmacology concepts to real-world practice.

Author Biography

Evelyn Salerno, is Courtesy Professor, School of Nursing, Florida International University; Clinical Assistant Professor, Nova-Southeastern College of Pharmacy, Miami, Florida.

Table of Contents

PART 1 BASIC CONCEPTS
Unit 1 Principles of Pharmacology
Orientation to Pharmacology
1(10)
Historical Trends
2(1)
Names of Drugs
3(1)
Sources of Drugs
4(1)
Drug Classification
4(2)
The Scope of Nursing Management of Drug Therapy
6(1)
The Nursing Process and Drug Administration
7(1)
Goals of This Text
8(1)
Summary
9(2)
Legal and Ethical Aspects of Medication Administration
11(21)
United States Drug Legislation
12(4)
Canadian Drug Legislation
16(3)
Standardization of Drugs
19(1)
International Drug Control
19(1)
Investigational Drugs
20(5)
Nurses and Drug Research
25(1)
Nursing Legislation
25(4)
Ethical Considerations
29(1)
Nursing Practice
30(1)
Summary
30(2)
Principles of Drug Action
32(21)
General Properties of Drugs
33(1)
Mechanisms of Drug Action
33(12)
Side Effects/Adverse Reactions
45(5)
Nursing Management of Drug Therapy
50(1)
Summary
51(2)
Unit 2 The Nursing Process and Pharmacology
Assessment, Nursing Diagnosis, and Planning
53(20)
Assessment
54(11)
Analysis of Data
65(1)
Nursing Diagnoses/Collaborative Problems
65(4)
Planning for Drug Therapy
69(1)
Summary
70(3)
Implementation and Evaluation
73(37)
Implementation
74(32)
Evaluation
106(1)
Summary
107(3)
Unit 3 Biopsychosocial Aspects of Pharmacology
Cultural and Psychologic Aspects of Drug Therapy
110(16)
Cultural Influences on Health Care
111(6)
Ethnic and Racial Differences in Drug Response
117(1)
Psychologic Aspects
118(2)
Self-Treatment
120(3)
Summary
123(3)
Maternal and Child Drug Therapy
126(20)
Childbearing Clients
127(5)
Children
132(12)
Summary
144(2)
Drug Therapy for Older Adults
146(10)
Physiologic Changes of Aging
147(2)
Alterations in Pharmacokinetics
149(1)
Alterations in Pharmacodynamics
149(1)
Ineffective Management of the Self-Medication Regimen
150(1)
Medications in Older Adults
150(4)
Summary
154(2)
Substance Misuse and Abuse
156(33)
Substance Abuse
157(1)
Drug Testing
158(1)
Etiologic Factors
159(1)
Pharmacologic Basis of Dependence and Tolerance
160(1)
Pathophysiologic Changes
160(3)
Cultural Aspects of Substance Abuse
163(1)
Types of Drugs Most Commonly Abused
163(22)
Summary
185(4)
Client Education for Self-Administration of Medication
189(15)
Assessment
190(5)
Nursing Diagnosis
195(1)
Planning
196(1)
Implementation
197(3)
Evaluation
200(1)
Documentation
201(1)
Summary
201(3)
Unit 4 Current Issues in Pharmacology
Over-the-Counter Medications
204(28)
Changing a Drug from Prescription to Over-the-Counter Status
205(1)
Drug Marketing
206(1)
Consumer Education for Over-the-Counter Drugs
206(2)
Selected Over-the-Counter Drug Categories
208(22)
Summary
230(2)
Complementary and Alternative Pharmacology
232(15)
Remedies That Might Help
235(5)
Remedies That Might Harm
240(2)
Consumer Education for Complementary and Alternative Therapies
242(1)
Summary
243(4)
PART II CLINICAL CONCEPTS
Unit 5 Drugs Affecting the Central Nervous System
Overview of the Central Nervous System
247(9)
Brain
248(2)
Spinal Cord
250(1)
Cell Types
251(1)
Blood-Brain Barrier
252(1)
Functional Systems of the Central Nervous System
253(1)
Synaptic Transmission in the Central Nervous System
254(1)
Summary
255(1)
Analgesics
256(46)
Issues Affecting Pain Management
257(2)
Components and Concepts of Pain
259(9)
Opioid Analgesics
268(15)
Opioid Antagonists
283(2)
Opioid Agonist-Antagonist Agents
285(3)
Nonopioid Analgesics
288(1)
Nonsteroidal Antiinflammatory Drugs
289(7)
Thromboxane A2
296(1)
Other Drugs
296(3)
Adjuvant Medications
299(1)
Summary
299(3)
Anesthetics
302(23)
General Anesthesia
303(1)
Mechanism of Action
303(1)
Stages of General Anesthesia
303(1)
Significant Drug Interactions
304(1)
Special Considerations
305(3)
Types of General Anesthetics
308(9)
Local Anesthesia
317(1)
Surface or Topical Anesthesia
317(1)
Local Anesthetics
318(4)
Anesthesia by Injection
322(1)
Summary
323(2)
Antianxiety, Sedative, and Hypnotic Drugs
325(25)
Physiology of Sleep
326(1)
Use in Children
327(1)
Use in Older Adults
328(3)
Benzodiazepines
331(10)
Barbiturates
341(3)
Miscellaneous Sedatives and Hypnotics
344(4)
Summary
348(2)
Anticovulsants
350(27)
Classification of Seizures
351(1)
Types of Seizures
351(1)
Relationship of Age to Seizures
352(1)
Anticonvulsant Therapy
352(6)
Hydantoins
358(4)
Barbiturates
362(2)
Succinimides
364(2)
Benzodiazepines
366(1)
Miscellaneous Anticonvulsants
367(8)
Summary
375(2)
Central Nervous System Stimulants
377(15)
Anorexiant Drugs
378(3)
Amphetamines
381(4)
Other Central Nervous System Stimulants
385(5)
Summary
390(2)
Psychotherapeutic Drugs
392(38)
The Central Nervous System and Emotions
393(1)
The Role of Drug Therapy in Psychiatry
393(3)
Antipsychotic or Neuroleptic Agents
396(16)
Therapy of Affective Disorders
412(15)
Summary
427(3)
Unit 6 Drugs Affecting the Autonomic Nervous System
Overview of the Autonomic Nervous System
430(10)
Reflex Control System
431(1)
Classification of the Nervous System
431(1)
Differences Between the Parasympathetic and Sympathetic Nervous Systems
432(1)
Neurohumoral Transmission
432(6)
Summary
438(2)
Drugs Affecting the Parasympathetic Nervous System
440(18)
Autonomic Drugs
441(1)
Cholinergic Drugs
441(4)
Cholinergic Blocking Drugs: Muscarinic Blocking Drugs
445(5)
Ganglionic Drugs
450(1)
Ganglionic Stimulating Drugs
450(5)
Ganglionic Blocking Drugs
455(1)
Summary
456(2)
Drugs Affecting the Sympathetic (Adrenergic) Nervous System
458(33)
Adrenergic Drugs
459(19)
Adrenergic Blocking Drugs
478(9)
Serotonergic Drugs
487(2)
Summary
489(2)
Drugs for Specific Dysfunctions of the Central and Peripheral Nervous Systems
491(29)
Parkinson's Disease
492(12)
Myasthenia Gravis
504(3)
Dementia
507(1)
Alzheimer's Disease
508(3)
Skeletal Muscle Relaxants
511(7)
Summary
518(2)
Unit 7 Drugs Affecting the Cardiovascular System
Overview of the Cardiovascular System
520(11)
The Heart
521(7)
Coronary Vascular Supply
528(1)
Summary
529(2)
Cardiac Glycosides
531(16)
Heart Failure
532(3)
Digitalis Glycosides
535(8)
Miscellaneous Agents
543(2)
Summary
545(2)
Antidysrhythmics
547(20)
Disorders in Cardiac Electrophysiology
548(2)
Group I-A Drugs
550(6)
Group I-B Drugs
556(3)
Group I-C Drugs
559(1)
Group I Drugs (A, B, C)
560(1)
Group II Drugs
560(1)
Group III Drugs
560(4)
Group IV: Miscellaneous Drug Group
564(1)
Unclassified Antidysrhythmic Drug
564(1)
Summary
565(2)
Antihypertensives
567(31)
Definition of Hypertension
568(1)
Classification of Hypertension
568(1)
Physiologic Control of Blood Pressure
569(2)
Antihypertensive Therapy
571(4)
Diuretic Drugs
575(1)
Adrenergic Inhibiting (Sympatholytic) Agents
575(11)
Angiotensin-Converting Enzyme Inhibitors
586(2)
Angiotensin II Receptor Antagonists
588(1)
Calcium Antagonists
589(1)
Vasodilators
589(6)
Summary
595(3)
Calcium Channel Blockers
598(7)
Overview
599(4)
Summary
603(2)
Vasodilators and Antihemorrheologic Agents
605(9)
Angina
606(1)
Vasodilators
606(4)
Peripheral Vascular Disease
610(2)
Hemorrheology
612(1)
Summary
613(1)
Unit 8 Drugs Affecting the Blood
Overview of the Blood
614(6)
Blood Volume
615(1)
Blood Composition
615(2)
Blood Coagulation
617(1)
Blood Types
618(1)
Summary
619(1)
Anticoagulants, Thrombolytics, and Blood Components
620(29)
Anticoagulant Drugs
621(12)
Thrombolytic Drugs
633(3)
Antiplatelet Drugs
636(2)
Antihemophilic Drugs
638(2)
Hemostatic Drugs
640(3)
Blood and Blood Components
643(4)
Summary
647(2)
Antihyperlipidemic Drugs
649(14)
Hyperlipidemic Disorders
650(3)
Bile Acid Sequestering Agents
653(3)
Additional Antihyperlipidemic Agents
656(4)
Reductase Inhibitors
660(1)
Summary
661(2)
Unit 9 Drugs Affecting the Urinary System
Overview of the Urinary System
663(5)
Anatomy and Physiology of the Kidney
664(1)
Physiologic Regulation by the Kidney
665(1)
Summary
666(2)
Diuretics
668(15)
Proximal Tubule Diuretics: Carbonic Anhydrase Inhibitors
669(2)
Diluting Segment Diuretics: Thiazide and Thiazide-Type Drugs
671(5)
Loop Diuretics
676(2)
Distal Tubule Diuretics/Potassium-Sparing Diuretics
678(1)
Osmotic Diuretics
679(2)
Diuretic Combinations
681(1)
Summary
681(2)
Uricosuric Drugs
683(9)
Gout
684(7)
Summary
691(1)
Drug Therapy for Renal System Dysfunction
692(7)
Acute vs. Chronic Renal Failure
693(1)
Signs and Symptoms of Renal Failure or Insufficiency
693(1)
Measurement of Renal Function
693(1)
Special Needs of the Client with Renal Failure
694(1)
Selected Drug Modifications in Renal Failure
695(2)
Summary
697(2)
Unit 10 Drugs Affecting the Respiratory System
Overview of the Respiratory System
699(4)
Respiratory Tract Secretions
700(1)
Bronchial Smooth Muscle
701(1)
Control of Respiration
701(1)
Summary
702(1)
Mucokinetic, Bronchodilator, and Antiasthmatic Drugs
703(27)
Mucokinetic Drugs
704(1)
Diluents
704(1)
Aerosol Therapy
705(1)
Mucolytic Drugs
706(2)
Drugs That Antagonize Bronchial Secretions
708(1)
Bronchodilator Drugs
708(3)
Sympathomimetic Drugs
711(7)
Anticholinergic Bronchodilator Agent
718(1)
Leukotriene Antagonists
719(1)
Xanthine Derivatives
720(4)
Prophylactic Antiasthmatic Drugs
724(1)
Corticosteroids
725(2)
Summary
727(3)
Oxygen and Miscellaneous Respiratory Agents
730(17)
Drugs That Affect the Respiratory Center
731(6)
Cough Suppressants
737(1)
Histamine
738(3)
Antihistamines
741(3)
Serotonin
744(1)
Antiserotonins
745(1)
Summary
745(2)
Unit 11 Drugs Affecting the Gastrointestinal System
Overview of the Gastrointestinal Tract
747(5)
Mouth (Oral Cavity)
748(1)
Pharynx
748(1)
Esophagus
749(1)
Stomach
749(1)
Liver
750(1)
Gallbladder
750(1)
Pancreas
750(1)
Small Intestine
750(1)
Large Intestine
750(1)
Summary
751(1)
Drugs Affecting the Gastrointestinal Tract
752(35)
Drugs That Affect the Upper Gastrointestinal Tract
753(1)
Drugs That Affect the Mouth
753(2)
Drugs That Affect the Stomach
755(21)
Drugs Used to Treat Inflammatory Bowel Disease
776(1)
Drugs That Affect the Lower Gastrointestinal Tract
777(2)
Laxatives
779(2)
Antidiarrheals
781(4)
Summary
785(2)
Unit 12 Drugs Affecting the Visual and Auditory Systems
Overview of the Eye
787(3)
Summary
789(1)
Ophthalmic Drugs
790(21)
Antiglaucoma Agents
794(6)
Mydriatic and Cycloplegic Agents
800(2)
Antiinfective/Antiinflammatory Agents
802(4)
Topical Anesthetic Agents
806(1)
Other Ophthalmic Preparations
807(2)
Summary
809(2)
Overview of the Ear
811(3)
Anatomy and Physiology
812(1)
Common Ear Disorders
812(1)
Summary
813(1)
Drugs Affecting the Ear
814(5)
Antibiotic Ear Preparations
815(1)
Corticosteroid Ear Preparations
815(1)
Other Otic Preparations
815(1)
Drug-Induced Ototoxicity
816(1)
Summary
817(2)
Unit 13 Drugs Affecting the Endocrine System
Overview of the Endocrine System
819(10)
Hormones
820(1)
Pituitary Gland
821(2)
Thyroid Gland
823(2)
Parathyroid Glands
825(1)
Adrenal Glands
826(1)
Pancreas
826(1)
Summary
827(2)
Drugs Affecting the Pituitary
829(7)
Anterior Pituitary Hormones
830(2)
Posterior Pituitary Hormones
832(2)
Summary
834(2)
Drugs Affecting the Parathyroid and Thyroid Glands
836(14)
Drugs Affecting the Parathyroid
837(3)
Drugs Affecting the Thyroid
840(8)
Summary
848(2)
Drugs Affecting the Adrenal Cortex
850(11)
Glucocorticoids
851(6)
Mineralocorticoids
857(1)
Antiadrenals (Adrenal Steroid Inhibitors)
858(1)
Summary
859(2)
Drugs Affecting the Pancreas
861(21)
Diabetes Mellitus
862(1)
Insulin Preparations
863(8)
Oral Hypoglycemic Agents
871(6)
Hyperglycemic Agents
877(3)
Summary
880(2)
Unit 14 Drugs Affecting the Reproductive System
Overview of the Female and Male Reproductive Systems
882(6)
Endocrine Glands
883(1)
Pituitary Gonadotropic Hormones
883(1)
Female Reproductive System
883(1)
Male Reproductive System
884(3)
Summary
887(1)
Drugs Affecting Women's Health and the Female Reproductive System
888(19)
Gonadotropin-Releasing Hormone
889(1)
Gonadotropin-Releasing Hormone Agonist
889(2)
Nonpituitary Chorionic Gonadotropin
891(1)
Menotropins
892(1)
Female Sex Hormones
893(4)
Oral Contraceptives
897(7)
Ovulatory Stimulants and Drugs Used for Infertility
904(1)
Summary
905(2)
Drugs for Labor and Delivery
907(7)
Drugs That Affect the Uterus
908(5)
Drugs That Inhibit Lactation
913(1)
Summary
913(1)
Drugs Affecting the Male Reproductive System
914(6)
Testosterone
915(2)
Benign Prostatic Hyperplasia
917(2)
Summary
919(1)
Drugs Affecting Sexual Behavior
920(8)
Drugs That Impair Libido and Sexual Gratification
921(2)
Drugs That Enhance Libido and Sexual Gratification
923(1)
Drugs That Stimulate Sexual Behavior
924(2)
The Nurse's Role in Human Sexuality
926(1)
Summary
926(2)
Unit 15 Drugs Used in Neoplastic Diseases
Principles of Antineoplastic Chemotherapy
928(12)
Cell Kinetics
929(1)
Principles of Chemotherapy
930(1)
Combination Chemotherapy
931(1)
Toxic Effects of Chemotherapy
932(1)
Age-Related Considerations in Chemotherapy
932(6)
Summary
938(2)
Antineoplastic Chemotherapy Agents
940(26)
Overview of Drug Effects
941(1)
Antimetabolite Drugs
941(9)
Alkylating Drugs
950(4)
Nitrosureas
954(1)
Alkylator-Like Drugs
954(2)
Antibiotic Antitumor Drugs
956(1)
Mitotic Inhibitors
957(2)
Miscellaneous Antineoplastic Agents
959(4)
Cancer Chemotherapy Research
963(1)
Summary
964(2)
Unit 16 Drugs Used in Infectious Diseases and Inflammation
Overview of Infections, Inflammation, and Fever
966(13)
Infections
967(1)
Inflammation
968(1)
Fever
969(1)
Antimicrobial Therapy
969(8)
Summary
977(2)
Antibiotics
979(34)
Penicillins and Related Antibiotics
982(6)
Cephalosporins and Related Products
988(3)
Macrolide Antibiotics
991(2)
Lincosamides
993(2)
Aminoglycosides
995(2)
Tetracyclines
997(1)
Chloramphenicol (Chloromycetin)
998(2)
Fluoroquinolones
1000(1)
Miscellaneous Antibiotics
1001(3)
Urinary Tract Antimicrobials
1004(6)
Urinary Tract Analgesic
1010(1)
Summary
1010(3)
Antifungal and Antiviral Drugs
1013(28)
Antifungal Drugs
1014(7)
Antiviral Drugs
1021(18)
Summary
1039(2)
Other Antimicrobial Drugs and Antiparasitic Drugs
1041(32)
Drugs Used in the Treatment of Malaria
1042(6)
Drugs Used in the Treatment of Tuberculosis
1048(12)
Drugs Used in the Treatment of Amebiasis
1060(2)
Other Drugs Used in Amebiasis
1062(1)
Drugs Used in the Treatment of Other Protozoan Diseases
1062(1)
Drugs Used in the Treatment of Helminthiasis
1063(6)
Drugs Used in the Treatment of Leprosy
1069(2)
Summary
1071(2)
Unit 17 Drugs Affecting the Immunologic System
Overview of the Immunologic System
1073(6)
The Immune System
1074(1)
Immunocompetent Cells
1075(1)
Antibodies
1076(1)
Immunity
1076(2)
Summary
1078(1)
Serums, Vaccines, and Other Immunizing Agents
1079(15)
Overview
1080(2)
Current Issues
1082(2)
Side Effects/Adverse Reactions
1084(9)
Summary
1093(1)
Immunosuppressants and Immunomodulators
1094(21)
Immunosuppressants
1097(7)
Immunomodulators
1104(9)
Summary
1113(2)
Unit 18 Drugs Affecting the Integumentary System
Overview of the Integumentary System
1115(3)
Structure of the Skin
1116(1)
Functions of the Skin
1116(1)
Appendages of the Skin
1117(1)
Summary
1117(1)
Dermatologic Drugs
1118(21)
Skin Disorders
1119(5)
General Dermatologic Preparations
1124(1)
Prophylactic Agents
1125(2)
Therapeutic Agents
1127(10)
Summary
1137(2)
Debriding Agents
1139(10)
Overview of Pressure Sores
1140(3)
Pharmacologic Management of Pressure Sores
1143(5)
Summary
1148(1)
Unit 19 Intravenous and Nutritional Therapy
Vitamins and Minerals
1149(20)
Vitamins
1150(15)
Minerals
1165(2)
Summary
1167(2)
Fluids and Electrolytes
1169(16)
Fluids
1170(3)
Electrolytes
1173(10)
Summary
1183(2)
Enteral and Parenteral Nutrition
1185(13)
Enteral Nutrition
1186(5)
Parenteral Nutrition
1191(6)
Summary
1197(1)
Unit 20 Miscellaneous Agents
Antiseptics, Disinfectants, and Sterilants
1198(11)
Medical and Surgical Asepsis
1199(1)
Antiseptics and Disinfectants
1199(8)
Sterilants
1207(1)
Summary
1207(2)
Diagnostic Agents
1209(13)
Radiopaque Agents for Visualizing Organ Structure
1210(2)
Agents for Evaluating Organ Function
1212(4)
Agents for Screening and Monitoring Immune Disorders and Immune Status
1216(4)
Summary
1220(2)
Poisons and Antidotes
1222(14)
Detection of Poisons
1223(2)
Poison Control Centers
1225(1)
Classification of the Action of Poisons
1225(2)
Specific Poisons, Symptoms, and Suggested Emergency Treatment
1227(4)
Prevention of Poisoning
1231(1)
Common Poisons
1232(2)
Summary
1234(2)
Appendix A Sugar-Free Products 1236(1)
Appendix B Alcohol-Free Products 1237(1)
Appendix C Drugs That Change Urine or Stool Color 1238(1)
Appendix D Time to Draw Blood for Specific Medications 1239(1)
Appendix E Additional New Drug Products 1240(2)
Appendix F Top 100 Brand-Name Drugs by Prescription 1242(2)
Appendix G Oral Transmucosal Fentanyl 1244(1)
Appendix H System Used to Rate HIV Treatment Recommendations 1245

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