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Stem Cells, Craniofacial Development and Regeneration,9781118498026
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Stem Cells, Craniofacial Development and Regeneration



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Stem Cells, Craniofacial Development and Regeneration is an introduction to stem cells with an emphasis on their role in craniofacial development. Divided into five sections, chapters build from basic introductory information on the definition and characteristics of stem cells to more indepth explorations of their role in craniofacial development. Section I covers embryonic and adult stem cells with a focus on the craniofacial region, while sections II-IV cover the development and regeneration of craniofacial bone, tooth, temporomandibular joint, salivary glands and muscle. Concluding chapters describe the current, cutting-edge research utilizing stem cells for craniofacial tissue bioengineering to treat lost or damaged tissue.

The authoritative resource for dentistry students as well as craniofacial researchers at the graduate and post-graduate level, Stem Cells, Craniofacial Development and Regeneration explores the rapidly expanding field of stem cells and regeneration from the perspective of the dentistry and craniofacial community, and points the way forward in areas of tissue bioengineering and craniofacial stem cell therapies.

Author Biography

George T.-J. Huang, DDS, MSD, DSc, is the Director for Stem Cells and Regenerative Therapies in the College of Dentistry at the University of Tennessee Health Science Center.

Irma Thesleff, DDS, PhD, is the Research Director of the Developmental Biology Program at the Institute of Biotechnology at the University of Helsinki.

Table of Contents

Section I : Development and regeneration of craniofacial tissues and organs

1. Molecular blueprint for craniofacial morphogenesis and development
Paul A. Trainor*, PhD

2. Cranial neural crest cells in craniofacial tissues and organs
Carolina Parada, Yang Chai*, DDS, PhD

3. Craniofacial intramembranous bone development and regeneration
David P. Rice*, BDS, FOrth, PhD, Ritva Rice, PhD

4. Temporomandibular joint development
Shuping Gu, DDS, PhD, YiPing Chen*, PhD

5. Craniofacial muscle development
Robert G. Kelly*, PhD

6. Tooth morphogenesis and renewal
Maria Jussila* MSc, Emma Juuri, DDS, MSc, Irma Thesleff , PhD

7. Reptile tooth regeneration
Joy M. Richman* PhD, DMD, John A. Whitlock, PhD, John Abramyan, PhD

8. Root development
Brian L. Foster, PhD, Francisco H. Nociti, Jr., DDS, PhD, Martha J. Somerman*, DDS, PhD

9. Systems Biology of Early Tooth Development
Daniel J. O'Connell, PhD, Joshua W. K. Ho, PhD, Richard L. Maas*, MD, PhD

Section II: Stem cells and their niches in craniofacial tissues

10. Stem cells, induced pluripotent stem cells and their differentiation to specified lineage fates
George T.-J. Huang,* DDS, MSD, DSc, Xiaoying Zou, DDS, MD, Xing Yan, DDS, PhD, Kyle J. Hewitt, PhD, Yulia Shamis, PhD, Jonathan A. Garlick,* DDS, PhD

11. Bone marrow mesenchymal stem cells  (asked)
Songtao Shi, DDS, PhD, Stan Gronthos*, PhD

12. Adipose tissue-derived stem cells and their regeneration potential
Jeffrey Gimble*, MD, PhD, Maryam Rezai Rad, Shaomian Yao, PhD

13. Skeletal muscle stem cells; their origin and niche factors
Johannes W. Von den Hoff *, PhD, Sander Grefte, PhD

14. Stem cells in salivary gland development and regeneration
Isabelle M.A. Lombaert, PhD, Matthew P. Hoffman,* BDS, PhD

15. Stem/progentinor cells of dental and gingival tissue origin
Christian Morsczeck, MSc, PhD*, George T.-J. Huang, DDS, MSD, DSc, Songtao Shi, DDS, PhD

16. Regulation and differentiation potential of dental mesenchymal stem cells
Lei Wang, Christian Morsczeck, MSc, PhD, Stan Gronthos, PhD, Songtao Shi,* DDS PhD

17. An incisive look at stem cells: the mouse incisor as an emerging model for tooth renewal
Frederic Michon, Ph.D.*, Andrew H. Jheon, D.D.S., Ph.D., Kerstin Seidel, Ph.D., Ophir D. Klein,* M.D., Ph.D.

18. Mesenchymal stem cell niches in rodent tooth pulp
Jifen Feng, PhD, Paul T Sharpe*, PhD

Section III: Stem cell-mediated craniofacial tissue bioengineering

19. Bone bioengineering ? scaffolds, growth factors and stem cells
Christopher S. D. Lee, Ph.D., Christopher D. Hermann, Ph.D., Rolando Gittens, Rene Olivares-Navarrete, D.D.S., Ph.D., Zvi Schwartz, D.M.D., Ph.D., Barbara D. Boyan*, Ph.D.

20. Craniofacial tissue bioengineering and regeneration by endogenous stem cells
Nan Jiang, DDS, Mo Chen, PhD, Chang Hun Lee, PhD, Jian Zhou, DDS, PhD, Mildred C. Embree, DMD, PhD, Kimi Kong, PhD, Choko Cho, PhD, Avital Mendelson, PhD ,Ying Zheng, DDS, PhD, Hemin Nie, PhD, Jeremy J. Mao,* DDS, PhD

21. Stem cell-based bioengineering of craniofacial bone
David D. Lo, MD, Daniel Montoro, BS, Monica Grova, BS, Jeong S. Hyun, MD, Michael T. Chung, BS, Derrick C. Wan, MD, Michael T. Longaker*, MD, MBA

22. Muscle tissue engineering approaches
Johannes W. Von den Hoff *, PhD, Sander Grefte, PhD

23. Engineering of dental tissues: scaffolds and preclinical models
Na Yu, DDS, Adelina Plachokova, DDS, PhD, Fang Yang, PhD, X. Frank Walboomers, PhD, John A. Jansen,* DDS, PhD

24. Whole tooth engineering and cell sources
L. Keller, S Kuchler-Bopp*, PhD, Hervé Lesot*, PhD

25. Bioengineering of functional teeth
Takashi Tsuji*, PhD

26. Pulp and dentin regeneration
Misako Nakashima*, DDS, PhD, George T.-J. Huang , DDS, MSD, DSc

27. Bioengineering of roots and periodontal tissues
Songlin Wang*, DDS, PhD, Gang Ding, DDS, PhD, Fulan Wei, DDS, PhD, Yi Liu, DDS, PhD

28. Periodontal bioengineering strategies: the present status and some developing trends
Fa-Ming Chen, Ph.D., D.D.S., Yan Jin*, Ph.D., D.D.S.

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