Step-Up to USMLE Step 1 A High-Yield, Systems-Based Review for the USMLE Step 1

by Mehta, Samir

• ISBN13: 9780781780902
• ISBN10: 078178090X
• Edition: 3rd
• Format: Paperback
• Copyright: 2006-09-27
• Publisher: LWW

Summary

Now in its Third Edition, Step-Up is the most comprehensive systems-based review for the USMLE Step 1. The book has been widely acclaimed for its systems-based organization, which parallels the USMLE Step 1 content outline and helps students synthesize the information from their basic science courses. The popular, user-friendly format features numerous charts and diagrams and Quick Hits notes in the margins that help students integrate concepts across systems. For this edition, the author has added numerous clinical vignettes and new mnemonics to each chapter. Pharmacology has been further integrated into the systems-based format with new illustrations, tables, and references.

Table of Contents

Preface	vii
Acknowledgments	ix
System 1. Basic Concepts	1	(26)
DNA, RNA, and Protein	1	(4)
Bacterial Morphology and Genetics	5	(5)
Viral Genetics	10	(2)
Concepts in Pharmacology	12	(4)
Antiinfective Agents	16	(4)
Enzyme Kinetics	20	(2)
Biostatistics and Epidemiology	22	(5)
System 2. The Nervous System	27	(38)
Development	27	(1)
Congenital Malformations of the Nervous System	28	(1)
Major Receptors of the Nervous System	28	(1)
Meninges, Flow of Cerebrospinal Fluid (CSF), and Pathologic Trauma	29	(1)
Blood Supply to the Brain	29	(6)
Lesions of the Cerebral Cortex	35	(1)
Important Pathways of the Spinal Cord	36	(2)
Important Pathways of the Brain Stem and Cerebrum	38	(6)
Classic Lesions of the Spinal Cord	44	(1)
Hypothalamus	45	(1)
Thalamus	45	(1)
Cranial Nerves	46	(1)
Contents of the Cavernous Sinus	47	(1)
Sleep	48	(1)
Seizure Types	48	(1)
Degenerative Diseases	48	(5)
Demyelinating Diseases	53	(1)
Diseases That Cause Dementia	53	(1)
Acute Meningitis	53	(1)
Nervous System Tumors	54	(1)
Headache	54	(1)
Psychiatry and Behavioral Science	54	(2)
Ethics and the Role of the Physician	56	(9)
System 3. The Cardiovascular System	65	(28)
Development	65	(1)
Physiology and Pathology of Heart Function	66	(2)
Antiarrhythmics	68	(2)
Atherosclerosis	70	(2)
Familial Dyslipidemias	72	(1)
Hypertension	72	(4)
Aneurysms	76	(1)
Anthypertensive Agents	76	(4)
Ischemic Heart Disease	80	(2)
Congestive Heart Failure	82	(3)
Intrinsic Diseases of the Heart	85	(2)
Cardiac Neoplasms	87	(2)
Diseases of the Pericardium	89	(2)
Shock	91	(1)
Cardiovascular Manifestations of Systemic Diseases	91	(1)
Drugs that Cause Adverse Effects to the Cardiovascular System	92	(1)
System 4. The Respiratory System	93	(20)
Development	93	(1)
Physics and Function of the Lung	94	(5)
Control of Breathing	99	(2)
Lung Defenses	101	(1)
Adult Respiratory Distress Syndrome and Neonatal Respiratory Distress Syndrome	102	(1)
Pneumothorax	102	(1)
Pulmonary Vascular Diseases	103	(1)
Chronic Obstructive Pulmonary Disease (COPD)	103	(2)
Interstitial Lung Disease (ILD)	105	(1)
Environmental Lung Diseases (Pneumoconiosis)	106	(1)
Respiratory Infections	106	(4)
Cystic Fibrosis (CF)	110	(1)
Lung Neoplasms	111	(1)
Drugs that Cause Adverse Effects to the Respiratory System	112	(1)
System 5. The Gastrointestinal System	113	(26)
Innervation and Blood Supply of the Gastrointestinal Tract	113	(1)
Hormones of the Gastrointestinal System	114	(1)
Important Congenital Malformations of the Gastrointestinal System	114	(1)
The Oropharynx, Esophagus, and Stomach	114	(5)
The Small Intestine, Large Intestine, and Rectum	119	(2)
Location of Absorption of Vitamins, Minerals, and Nutrients	121	(1)
Common Clinical Disorders of the Small Intestine, Large Intestine, and Rectum	122	(4)
Malabsorption Syndromes of the Small Intestine	126	(1)
Neoplastic Polyps	127	(1)
The Hepatobiliary System	128	(9)
The Pancreas	137	(1)
Bugs of the Gastrointestinal Tract	138	(1)
System 6. The Renal System	139	(22)
Development	139	(1)
Gross Description of the Kidney	139	(1)
Normal Kidney Function	140	(6)
Glomerular Diseases	146	(3)
Urinary Tract Infections (UTIs)	149	(3)
Major Causes of Acute Renal Failure	152	(3)
Chronic Renal Failure (CRF) and Uremia	155	(2)
Kidney Stone Formation	157	(1)
Adult Polycystic Kidney Disease (APKD) Versus Normal Kidney	157	(1)
Renal Cancers	158	(1)
Therapeutic Agents	159	(2)
System 7. The Endocrine System	161	(24)
Development	161	(1)
Congenital Malformations	162	(1)
Hormones	162	(3)
Calcium Homeostasis	165	(1)
Insulin and Glucagon	165	(3)
Blood Glucose Levels	168	(4)
Diabetes Mellitus	172	(3)
Pituitary Disorders	175	(1)
Diabetes Insipidus	175	(1)
The Adrenal Glands	176	(3)
Thyroid	179	(4)
Parathyroid Pathology	183	(1)
Multiple Endocrine Neoplasia (MEN) Syndromes	184	(1)
System 8. The Reproductive System	185	(32)
Determination of Sex	185	(1)
Female Reproductive System Development	185	(1)
Male Reproductive System Development	185	(1)
Congenital Malformations	186	(1)
Genetic Abnormaltities	187	(1)
Menarche, Menstruation, and Menopause	187	(9)
Pregnancy and Its Associated Complications	196	(5)
Gynecologic Diagnostic Tests	201	(1)
Sexually Transmitted Diseases (STDs)	201	(1)
Female Gynecologic Neoplasms	201	(2)
Breast Pathology	203	(1)
The Prostate	203	(1)
Testicular Pathology	203	(1)
Human Immunodeficiency Virus (HIV)	204	(7)
Psychosocial Development	211	(1)
Timeline of the Developmental Stages of Life	211	(1)
The Family Unit and Related Concepts	211	(2)
Sexuality	213	(2)
Rape	215	(1)
Suicide	215	(2)
System 9. The Musculoskeletal System	217	(24)
Development	217	(1)
Bone Function and Metabolism	218	(3)
Bone, Cartilage, and Joint Disease	221	(1)
Metabolic and Infectious Bone Disease	222	(3)
Systemic Lupus Erythematosus (SLE)	225	(1)
Other Connective Tissue Disorders	225	(1)
Brachial Plexus	225	(1)
Lumbosacral Plexus	225	(2)
Pain Management	227	(6)
Muscle Function and Dysfunction	233	(3)
The Inguinal Canal	236	(1)
Skin Disorders	236	(5)
System 10. The Hematopoietic and Lymphoreticular System	241	(26)
Hematopoiesis Timetable	241	(1)
The Cells	241	(1)
The Organs of the Lymphoreticular System	241	(3)
Red Blood Cell Physiology	244	(1)
Lymphocyte Differentiation	245	(1)
Immunoglobulins	245	(1)
Complement System	246	(1)
Hypersensitivity Reactions	247	(2)
Immunodeficiencies	249	(2)
Thrombosis and the Clotting Cascade	251	(3)
Antithrombotic Therapeutic Agents	254	(4)
Lymphoma	258	(1)
Leukemia	259	(1)
Anemia	259	(6)
Myeloproliferative Disorders	265	(2)
Appendix I: Drug Index	267	(46)
Appendix II: Bug Index	313	(18)
Appendix III: Most Common . . . Index	331	(7)
Glossary	338	(5)
Index	343