Targeted Therapy for Solid Tumors and Hematologic Malignancies

by Quintas-cardama, Alfonso

• ISBN13: 9781617618543
• ISBN10: 1617618543
• Edition: 1st
• Format: Hardcover
• Copyright: 2011-03-01
• Publisher: NOVA SCIENCE PUBLISHERS INC

Summary

Endocrine malignancies are rare tumours that are derived from endocrine cells located throughout the body. They encompass a heterogeneous group of malignancies, derived from different endocrine and neuroendocrine cells and have different clinically. The majority of endocrine neoplasms are benign, where the potential for invasion or metastasis is very low. Nevertheless, there is a group of endocrine neoplasms with malignant potential, and thus come under the management of medical oncology, often requiring systemic therapy. These include neuroendocrine tumours, anaplastic and medullary thyroid carcinomas, pheochromocytomas or paragangliomas, and adrenocortical carcinomas. While surgery continues to play a seminal role, the management of advanced endocrine neoplasia is more complex due to their rarity and heterogeneity. This book discusses the use of targeted therapy in the treatment of solid tumours and hematologic malignancies.

Table of Contents

Introduction

Therapeutic Agents & Approaches in the Age of Personalized Cancer Care

Optimizing the Development of Targeted Therapies in the Phase I Clinical Trial Setting

Targeted Therapy for Chronic Myeloid Leukemia

Targeted Therapy in the Treatment of Lymphocytic Leukemia

Targeted Therapy in Acute Myeloid Leukemia & Myelodysplastic Syndromes

Targeted Strategies for Multiple Myeloma

Targeted Therapy for Breast Cancer (Ricardo H. Ãílvarez & Vicente Valero)

Targeted Therapy in Gastrointestinal Carcinomas

Targeted Genitourinary cancers

Therapy in Head & Neck Malignancies

Therapeutic Approaches for Ovarian Cancer

Targeted Therapy for Endocrine Neoplasms

Tumors of the Central Nervous System

Targeting Tumors & Personalizing Individual Treatments for Radiation Therapy

Index

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