T-Cell Vaccination

by Zhang, Jingwu

• ISBN13: 9781604561784
• ISBN10: 1604561785
• Edition: 1st
• Format: Hardcover
• Copyright: 2008-09-01
• Publisher: NOVA SCIENCE PUBLISHERS INC

Summary

This book provides a comprehensive review of T cell vaccination which is a topic of significant interest in the field of Immunology. However, its academic value is not limited to basic research into the understanding of autoimmune T cell regulation in vivo, for the research is supported by preliminary clinical application. Indeed, T cell vaccinations have been tested in a number of promising clinical trials as a potential treatment for human auto-immune disease. T cell vaccination has thus evolved as one of the most interesting topics of immunology and translational medicine.

Table of Contents

Anti-Ergotypic Regulatory T Cells	p. 1
A Novel Population of CD8[alpha][alpha]+ Regulatory T Cells: Identification, Characterization and Induction	p. 11
T Cell Vaccination in Human Autoimmune Diseases	p. 25
Regulatory Mechanisms Induced by T Cell Vaccination in Humans	p. 39
T Cell Vaccination with CNS-Derived Cd4[superscript +] T-Cells in Multiple Sclerosis: Rationale and Immunological Responses	p. 59
Peptide and DNA Vaccination in EAE and Multiple Sclerosis	p. 77
Therapeutic Vaccination with T Cell Receptor Peptides: Challenges, Highlights and Future Directions	p. 103
Regulatory Anti-T-Cell Antibodies Induced by T Cell Vaccination	p. 131
The Role of Th1/Th2 Phenotypes in T cell Vaccination: Insights from a Mathematical Model	p. 139
Index	p. 159
Table of Contents provided by Blackwell. All Rights Reserved.