Toxicology Handbook

by Murray, Lindsay; Daly, Frank; Little, Mark; Cadogan, Mike

• ISBN13: 9780729539395
• ISBN10: 0729539393
• Edition: 2nd
• Format: Paperback
• Copyright: 2011-01-15
• Publisher: Elsevier Science Health Science

Summary

The Toxicology Handbook 2e is a practical, didactic guide to the approach, assessment and management of poisoned patients. It has been written for hospital-based doctors at all levels and describes the risk assessment-based approach pioneered by the principal authors. The concise layout enables the reader to quickly locate information in a poisoning emergency. The book also features locally relevant information on bites, stings and envenoming.This book will also be useful for ambulance service paramedics and pharmacists. It is established as a primary reference in the Australian Poisons Information Centres. all chapters and references reviewed and updated; major review of snake bite management and snake antivenoms in the light of new evidence new chapters on mushroom poisoning, plant poisoning, amphetamine abuse and solvent abuse new chapters on poisoning with newer anticonvulsant drugs, barbiturates, button batteries, chloral hydrate, local anaesthetic agents, quinine and tramadol new antidote chapter on intravenous lipid emulsion chapters reorganised for enhanced clinical usability - for example, consolidation of drugs of abuse enhanced electronic format

Table of Contents

Introduction

Who are the authors

Scope of the book

Handbook of acute management of common poisonings.

Hands on and practical approach.

Rationale for drugs included

How to use the book

Universal disclaimer

Clinical: Approach to the poisoned patient

Overview of approach to toxicology/toxinology

Principles of risk assessment-based approach

Resuscitation, Risk assessment, Supportive care, Decontamination, Investigations, Enhanced elimination, Antidotes, Disposition

Approach to specialist toxicology problems

Approach to special problems: Approach to snakebite, mushroom poisoning, plant poisoning

Toxidromes: Serotonin syndrome, Neuroleptic Malignant Syndrome, anticholinergic syndrome, cholinergic syndrome

Important poisoning manifestations and management: Seizures, coma, hypotension, delirium and agitation

Drugs of abuse and withdrawal syndromes: Alcohol, amphetamines, opiods, sedative hypnotics, body packers and stuffers

Investigations: Laboratory results: acidosis, anion gap and osmolar gap, recommended baseline investigations with interpretation. Unit conversion table: ECG interpretation in poisoning: Radiology.

Special populations: Paediatric poisoning: 1 tablet can kill (list), special precautions in management (overnight stay, paracetamol, risk of charcoal etc); Pregnancy and lactation and poisoning; and Geriatric poisoning

Toxic Drugs (78 chapters)

Approach to diagnosis, investigation and management of the poisoned patient with all of the common drug presentations. Updated with 8 new drug chapters as per readers nominations and feedback

Antidotes (29 chapters)

Detailed description of indications, contraindications, clinical administration and therapeutic end-points for all antidotes. New chapter on Intralipid, the latest development in antidote therapy

Toxinology (16 chapters)

Approach to snakebite, spider and marine envenoming. New chapter on tick envenoming

Antivenom (11 chapters)

Detailed description of indications, contraindications, clinical administration and therapeutic end-points for all antivenoms

Appendices Sample ECGs from poisoned patients; Drug concentrations and unit conversion chart; Guide to the management of allergic reaction to antivenom

Table of Contents provided by Publisher. All Rights Reserved.