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Since 1977, this outstanding book has been the immunology reference of choice for both veterinary students and practitioners. It's the only complete resource on the subject, featuring a straightforward presentation of basic immunologic principles with comprehensive information on the most significant immunological diseases and responses seen in domestic animals. This meticulously updated new edition explores the latest advances in the field and provides a wealth of clinical examples that illustrate and clarify important concepts. Clearly explains the general principles of immunology and applied immunology. Includes information on the most significant immunological diseases and immunological responses seen in domestic animals. Presents coverage of domestic mammal species in phylogenetic order: horse-cattle-sheep-pig-dog-cat-mouse-human. Provides clinical examples that demonstrate key immunologic principles. Offers expanded and updated references for all key sources in the literature. Features a new appendix that provides at-a-glance access to a comprehensive list of cytokines. Offers expanded coverage of complement and its critical importance to innate immunity. Discusses the latest information on the receptors of NK cells. Provides additional content on antibacterial peptides and their importance in inflammation and innate immunity. Includes coverage of newly identified cytokines, CD molecules, and IgA receptors. Examines new data on the functions of T cells, the effects of nematodes on eosinophils, and the latest DNA vaccines against West Nile virus and canine melanoma. Offers complete information on emerging diseases such as Stevens-Johnson syndrome, hemophagocytic syndrome, and autoimmune sarcolemmal disease in dogs, as well as common variable immunodeficiencies and immune mediated polysynovitis in horses.
Table of Contents
|The Defense of the Body|
|Innate Immunity: The Recognition of Invaders|
|Innate Immunity: Proinflammatory and Antimicrobial Mediators|
|Innate Immunity: Neutrophils and Phagocytosis|
|Innate Immunity: Macrophages and Recovery from Inflammation|
|Systemic Responses to Inflammation|
|Innate Immunity: The Complement System|
|Cell Signaling: Cytokines and Their Receptors|
|Antigens: Triggers of Adaptive Immunity|
|Dendritic Cells and Antigen Processing|
|The Major Histocompatibility Complex|
|Organs of the Immune System|
|Helper T Cells and Their Response to Antigen|
|B Cells and Their Response to Antigen|
|Antibodies: Soluble Antigen Receptors|
|How Antigen-Binding Receptors are made|
|T-Cell Function and the Destruction of Cell-Associated Invaders|
|The Third Lymphocyte Population: Natural Killer Cells|
|Regulation of Adaptive Immunity|
|Immunity in the Fetus and Newborn|
|Immunity at Body Surfaces|
|Vaccines and Their Production|
|The Use of Vaccines|
|Immunity to Bacteria and Fungi|
|Immunity to Viruses|
|Immunity to Parasites|
|Type I Hypersensitivity|
|Red Cell Antigens and Type II Hypersensitivity|
|Immune Complexes and Type III Hypersensitivity|
|Type IV Hypersensitivity: Delayed Hypersensitivity|
|Organ Graft Rejection|
|Resistance to Tumors|
|Autoimmunity: General Principles|
|Organ-Specific Autoimmune Diseases|
|The Systemic Immunological Diseases|
|Secondary Immunological Defects|
|Drugs and Other Agents That Affect the Immune System|
|The Evolution of the Immune System|
|Annotated List Of Selected CD Molecules|
|Some Selected Cytokines|
|Table of Contents provided by Publisher. All Rights Reserved.|