Veterinary Immunology: An Introduction

by Tizard, Ian R.

• ISBN13: 9781416049890
• ISBN10: 1416049894
• Edition: 8th
• Format: Paperback
• Copyright: 2008-02-14
• Publisher: Elsevier Science Health Science div

Summary

Since 1977, this outstanding book has been the immunology reference of choice for both veterinary students and practitioners. Its the only complete resource on the subject, featuring a straightforward presentation of basic immunologic principles with comprehensive information on the most significant immunological diseases and responses seen in domestic animals. This meticulously updated new edition explores the latest advances in the field and provides a wealth of clinical examples that illustrate and clarify important concepts. Clearly explains the general principles of immunology and applied immunology. Includes information on the most significant immunological diseases and immunological responses seen in domestic animals. Presents coverage of domestic mammal species in phylogenetic order: horse-cattle-sheep-pig-dog-cat-mouse-human. Provides clinical examples that demonstrate key immunologic principles. Offers expanded and updated references for all key sources in the literature. Features a new appendix that provides at-a-glance access to a comprehensive list of cytokines. Offers expanded coverage of complement and its critical importance to innate immunity. Discusses the latest information on the receptors of NK cells. Provides additional content on antibacterial peptides and their importance in inflammation and innate immunity. Includes coverage of newly identified cytokines, CD molecules, and IgA receptors. Examines new data on the functions of T cells, the effects of nematodes on eosinophils, and the latest DNA vaccines against West Nile virus and canine melanoma. Offers complete information on emerging diseases such as Stevens-Johnson syndrome, hemophagocytic syndrome, and autoimmune sarcolemmal disease in dogs, as well as common variable immunodeficiencies and immune mediated polysynovitis in horses.

Table of Contents

The Defense of the Body

How Inflammation is Triggered

Neutrophils and Their Products

Macrophages and the Later Stages of Inflammation

The Complement System

Cell Signaling: Cytokines and Their Receptors

Antigens: Triggers of Acquired Immunity

Dendritic Cells and Antigen Processing

The Major Histocompatibility Complex

Organs of the Immune System

Lymphocytes

Helper T Cells and Their Response to Antigen

B Cells and Their Response to Antigen

Antibodies: Soluble Antigen Receptors

How Antigen-Binding Receptors are Made

T-Cell Function and the Destruction of Cell-Associated Invaders

Regulation of Acquired Immunity

Immunity in the Fetus and Newborn

Immunity at Body Surfaces

Vaccines and Their Production

The Use of Vaccines

Acquired Immunity to Bacteria and Related Organisms

Acquired Immunity to Viruses

Acquired Immunity to Parasites

Type I Hypersensitivity

Red Cell Antigens and Type II Hypersensitivity

Immune Complexes and Type III Hypersensitivity

Type IV Hypersensitivity: Delayed Hypersensitivity

Organ Graft Rejection

Resistance to Tumors

Autoimmunity: General Principles

Organ-Specific Autoimmune Diseases

The Systemic Immunological Diseases

Primary Immunodeficiencies

Secondary Immunological Defects

Drugs and Other Agents that Affect the Immune System

The Evolution of the Immune System

Immunodiagnostic Techniques Appendix: Annotated List of Selected CD Molecules

Glossary

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