Preface | p. vii |
Acknowledgments | p. viii |
Frontline Diagnostic Urinalysis | p. 1 |
Types of Urinalyses | p. 3 |
Changing Times for Urinalysis | p. 3 |
Clinical Objectives of Urinalysis | p. 4 |
Clinical Utility of Diagnostic Wet Urinalysis | p. 5 |
Limitations of Diagnostic Wet Urinalysis | p. 6 |
References | p. 8 |
Anatomy and Physiology of the Urinary System | p. 9 |
Gross Anatomy and Histology of the Kidneys | p. 9 |
Anatomy and Histology of the Urinary Bladder | p. 12 |
Anatomy and Histology of the Urethra | p. 12 |
Four Major Processes in Urine Formation | p. 13 |
Pathway of Urine Formation | p. 13 |
References | p. 14 |
Specimen Collection, Preservation and Transportation | p. 15 |
Types of Transportation and Storage of Containers | p. 15 |
Noninstrumented Collection Procedures | p. 16 |
Instrumented Collection Procedures | p. 17 |
Chemical and Cellular Degeneration | p. 17 |
Techniques Used to Minimize Degeneration | p. 17 |
References | p. 19 |
Dipstick Urinalysis and Additional or Confirmatory Urine Chemical Testing | p. 21 |
Background | p. 21 |
Clinical Utility | p. 21 |
Manual Procedure for Dipstick Urinalysis | p. 22 |
Principles, Specificity, and Sensitivity of Dipstick Urinalysis | p. 22 |
Types of Specimens for Dipstick Urinalysis | p. 29 |
Sensitivity and Specificity of Urinary Reagent Test Strips | p. 29 |
Confirmatory Tests and Implications | p. 29 |
Clinical Significance of Positive Reactions | p. 30 |
Quality Control and Quality Assurance | p. 30 |
Future Trends | p. 31 |
References | p. 32 |
Wet Microscopic Urinalysis | p. 33 |
Automated and Semi-Automated Systems | p. 33 |
Clinical Utility of Wet Urinoscopy | p. 35 |
Laboratory Procedure | p. 37 |
Reporting | p. 37 |
Limitations of Wet Urine Microscopy | p. 38 |
Quality Control and Quality Assurance | p. 38 |
Dipstick Correlation with Wet Urinoscopy | p. 38 |
Techniques, Interpretations, and Other Considerations | p. 38 |
References | p. 39 |
Common Urine Sediment Entities | p. 41 |
Background Elements | p. 41 |
Hematopoietic Cells | p. 41 |
Urinary Epithelial Cells | p. 42 |
Urinary Casts | p. 43 |
Urinary Microorganisms | p. 45 |
Parasites | p. 45 |
Urinary Concretions | p. 45 |
Urinary Crystals | p. 45 |
Secretions | p. 48 |
Normal Wet Urinalysis Findings | p. 49 |
Physical and Chemical Examination of Urine | p. 49 |
Urine Sediment Examination | p. 49 |
Hematopoietic Cells in "Normal" Urine | p. 50 |
Epithelial Cells | p. 50 |
Casts in "Normal" Urine | p. 51 |
Microorganisms in "Normal" Urine | p. 51 |
Crystals in "Normal" Urine | p. 51 |
References | p. 51 |
Abnormal Wet Urinalysis Findings | p. 53 |
Physical and Chemical Examination of Urine | p. 53 |
Urine Sediment Examination | p. 54 |
Hemapoietic Cells in "Abnormal" Urine | p. 54 |
Epithelial Cells in "Abnormal" Urine | p. 55 |
Microorganisms Found in "Abnormal" Urine | p. 56 |
Crystals (Crystalluria) | p. 57 |
Concretions and Secretions | p. 58 |
Lipiduria | p. 58 |
Implications of "Abnormal" Wet Urinalysis Findings | p. 58 |
Indeterminate Wet Urinalysis Findings | p. 61 |
Approaches to "Indeterminate" Urine Sediment Entities | p. 62 |
Conclusion | p. 65 |
Quality Control and Quality Assurance Guidelines for the Wet Urinalysis Laboratory | p. 67 |
Quality Control and Assurance Guidelines | p. 67 |
Conclusion | p. 72 |
References | p. 72 |
Glossary | p. 73 |
Appendices | p. 81 |
Urinary System Disorders: Algorithms and Correlations | p. 81 |
Plates | p. 101 |
Index | p. 121 |
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