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This provocative new book posits how the tacit principle of "willful ignorance" has led to a deep divide between qualitative and quantitative modes of research that will increasingly constrain scientific progress unless bridged by a broadened conception of statistical methodology. It presents numerous examples, both hypothetical and real, to illustrate and support the main premise; offers a non-technical, historical survey of core statistical concepts; and speculates about the future evolution of statistics. Clinicians will find this book to be of particular interest, as will others interested in observational statistics.