Atherosclerosis Risks, Mechanisms, and Therapies

by Wang, Hong; Patterson, Cam

• ISBN13: 9781118285916
• ISBN10: 1118285913
• Edition: 1st
• Format: Hardcover
• Copyright: 2015-05-11
• Publisher: Wiley-Blackwell

Summary

Comprehensive and in-depth in its coverage, Atherosclerosis: Cellular, Molecular & Biochemical Mechanism and Novel Therapy reviews the recent progress in atherosclerosis research and offers cutting edge perspectives from experts in the field. Written by an international team of authors including leading physician-scientists, research experts and physicians, chapters are divided into four major sections, covering risk factors, cellular and molecular mechanisms, biochemical mechanisms and novel and future therapeutics.

Atherosclerosis: Cellular, Molecular & Biochemical Mechanism and Novel Therapy analyses recent progress from both conceptual and technological perspectives, suggesting new directions for atherosclerosis research and treatment for a growing population of researchers and clinicians in cardiovascular and related fields.

Author Biography

Hong Wang is a professor of pharmacology at Temple University School of Medicine. Her research focuses on mechanisms of vascular disease, using research approaches includinggenetic cloning, molecular biology, protein chemistry and immunohistochemistry. Dr. Wang is the author of numerous publications in peer reviewed journals including Cardiovascular Research, Atherosclerosis, Blood, and Trends in Cardiovascular Medicine.

Table of Contents

Preface (or Foreword):  Joe Loscalzo

 

Section I:             Risk Factors: old and new

1. LDL/VLDL/HDL; Daniel J. Rader
2. Diabetes/AGE; Ann Marry Schmidt
3. Inflammation; Cam Peterson,
4. Hcy; Lentz, Steven 

 

Section II:            Cellular and Molecular Mechanisms

                                                5.  Endothelial cells; Mukesh Jain

                                                6.  Vascular smooth muscle cells, Nicholas E. S. Sibinga

7.  Monocytes; Mark Finberg/Hong Wang

8.  Lymphocytes; Yang, Xiaofeng

9.  Scavenger receptors; Van Eck, Miranda

10.Phospholipases; Uwe Tietge,

11.Caviolin and atherosclerosis; Victor Rizzo

12.Regulatory lysosomes in atherosclerosis; Pin-lan Li

13.MicroRNA;  Yang, Xiaofeng

14. Paraoxonases; Reddy, Srinivasa

 

Section III:           Biochemical Mechanisms

                                                15. NO; Paul Huang

                                                16. CO; William Durante

                                                17. ROS; Minghui Zou

18. CRP; Yuqing Eugene Chen

                                                19. Methylation and SAH; Hong Wang

                                                20. Bioactive lipid and receptors; Pratico, Domenico

 

Section IV            Novel future therapeutic Approaches/strategies

(Henry Pownall will head this section and recruit people from inside and outside of book contributor list)

(A combined section with multiple subheadings, each describe a potential novel therapeutic strategy; going forward do better than just Statin)

21. Streptococcal Serum Opacity Factor; Henry Pownall

22. heme oxygenase/carbon monoxide system; William Durante