The Biochemical Basis of Neuropharmacology

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  • Edition: 8th
  • Format: Paperback
  • Copyright: 2002-10-17
  • Publisher: Oxford University Press
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This classic text gives a uniquely lucid and lively view of neurotransmitters, their role in nervous system function, and their involvement in the mechanisms of psychiatric drug action. For three decades it has served as an essential guide for students of neuroscience and psychopharmacology,residents in psychiatry and neurology, and clinicians and scientists. Both authoriative and very readable, it has been thoroughly updated for each edition. In the 8th Edition more space is devoted to clinical examples, subclasses of receptors that provide targets for new drugs, molecular genetics,the major problem of drug delivery to the brain, and the growing recognition of nicotin receptors in the brain and their possible involvement in Alxheimer's and Parkinson's diseases. In addition, the book's format has been enlarged and a second color added to many of the illustrations.

Author Biography

Jack R. Cooper, Ph.D., is Emeritus Professor of Pharmacology, Yale University School of Medicine Floyd E. Bloom, M.D., is Chairman, Department of Neuropharmacology, The Scripps Research Institute Robert H. Roth, Ph.D., is Professor of Pharmacology and Psychiatry, Yale University School of Medicine

Table of Contents

Introductionp. 1
Cellular Foundations of Neuropharmacologyp. 7
Molecular Foundations of Neuropharmacologyp. 39
Receptorsp. 65
Modulation of Synaptic Transmissionp. 85
Amino Acid Transmittersp. 105
Acetylcholinep. 151
Norepinephrine and Epinephrinep. 181
Dopaminep. 225
Serotonin (5-Hydroxytryptamine), Histamine, and Adenosinep. 271
Neuroactive Peptidesp. 321
Cellular Mechanisms in Learning and Memoryp. 357
Treating Neurological and Psychiatric Diseasesp. 373
Indexp. 401
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