Acknowledgements | |
Quotations | |
Preface to the First Edition | |
Preface to the Second Edition | |
Introduction and Preface to the Third Edition | |
Principles of Brain Function and Structure: 1 Genetics, Physiology and Chemistry | |
Introduction | |
Genetics | |
Brain chemistry and metabolism | |
The metabolism of glucose | |
Proteins and fatty acids | |
Cell membranes | |
Synapses | |
Receptors | |
Neurones | |
Neurotransmitters | |
Interrelationships among transmitters | |
Transmitter dispersal | |
CNS inflammation | |
Principles of Brain Function and Structure: 2 Anatomy | |
Introduction | |
The neuroanatomy of emotion | |
Individual anatomical structures | |
Ascending and descending limbic-system connections | |
Macrosystems | |
The basal ganglia and the re-entrant circuits | |
The ventral striatum and 'limbic striatum' | |
The ascending cholinergic systems | |
Cortical regions of interest | |
The cerebellum | |
Important Brain-Behaviour Relationships | |
Introduction | |
Important anatomical structures for understanding behaviour | |
Some specific behaviours | |
Limbic lobe disorders in a clinical context | |
Re-entrant circuits in a clinical context | |
The frontal lobes in a clinical context | |
Laterality | |
Classifications and Clinical Investigations | |
Introduction | |
Signs, symptoms, syndromes and disease | |
Classification in psychiatry | |
Clinical investigation | |
Personality Disorders | |
General introduction | |
Introduction to the concept of personality | |
Genetics | |
Somatic variables | |
Metabolic and biochemical findings | |
Neurophysiological and neurological data | |
Some outstanding issues | |
Anxiety Disorders | |
Introduction | |
Genetics | |
Somatic variables | |
Metabolic and biochemical findings | |
Neurochemical investigations | |
Neurophysiological and neurological data | |
Imaging | |
Obsessive-compulsive disorder | |
Post-traumatic stress disorder | |
Some outstanding issues | |
The Schizophrenias | |
Introduction | |
Genetics | |
Somatic variables | |
Metabolic and biochemical findings | |
Neurochemical investigations | |
Neurophysiological and neurological data | |
Some outstanding issues | |
Affective Disorders | |
Introduction | |
Genetics | |
Metabolic and biochemical findings | |
Neurochemical investigations | |
Neurophysiological and neurological data | |
Some outstanding issues | |
The Addictions and Disorders of Motivation | |
Introduction | |
Disorders of motivation | |
Conditioning | |
Genetics | |
Metabolic and biochemical findings | |
Neurophysiological and neurological data | |
Some outstanding issues | |
Epilepsy | |
Introduction | |
Prevalence and clinical characteristics | |
Classification | |
Genetics | |
Symptomatic epilepsy | |
Biochemical findings | |
Investigation and differential diagnosis | |
Psychiatric disorders in epilepsy | |
Cognitive deterioration and epilepsy | |
Some outstanding issues | |
The Dementias | |
Introduction | |
Definition | |
Prevalence | |
Diagnosis and classification | |
Alzheimer's disease | |
Dementia of frontal-lobe type | |
Focal cortical atrophies | |
Dementia with Lewy bodies | |
Vascular dementias | |
Other forms of dementia | |
Further causes of dementia | |
Some outstanding issues | |
Biological Treatments | |
Introduction | |
Pharmacology: pharmacokinetics and pharmacodynamics | |
Antidepressants | |
Antipsychotic drugs | |
Anxiolytics and hypnotics | |
Beta-Adrenergic blockers | |
Lithium | |
Anticonvulsants | |
Drugs for the treatment of dementia | |
Medications for the addictions | |
Brain-stimulation therapies | |
Sleep-deprivation therapy | |
Epilogue: Progress toward a Neuroanatomically, Biological-psychiatrically Informed Classification Scheme in Psychiatry | |
References | |
Index | |
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