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9780199797608

The Bipolar Brain Integrating Neuroimaging and Genetics

by
  • ISBN13:

    9780199797608

  • ISBN10:

    0199797609

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2012-07-05
  • Publisher: Oxford University Press
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Summary

Bipolar disorder is one of the most common, and disabling, conditions affecting human kind. Each year, millions of individuals struggle with the effects of this illness. Although clinically well recognized for decades, if not centuries, the causes of this condition remain incompletely understood. However, in the past decade, significant technological advances in both neuroimaging and genetic research have revealed clues about the neurophysiological basis of bipolar illness. In this book, leading experts in neuroimaging and genetics discuss recent discoveries in bipolar disorder that identify both the structural, functional and chemical brain changes that seem to underlie this condition, as well as the possible genetic causes of these brain events. Based upon these discussions, the book then integrates these diverse considerations to develop a specific neurophysiological model of bipolar disorder. This model provides a resource to guide clinicians and patients as they struggle to understand this illness, as well as a guide for future investigations into the causes of bipolar disorder. With this guide in hand, this book will lead to a new framework for understanding bipolar disorder in order to, ultimately, develop improved therapies for affected individuals and novel strategies to prevent the onset in children at risk for this condition.

Table of Contents

How neuroimaging informs models of bipolar disorder
Brain imaging techniques and their application to bipolar disorder
Structural brain abnormalities in bipolar disorder
Functional brain imaging in bipolar disorder
Neurochemical and metabolic imaging in bipolar disorder
Neuroimaging studies of bipolar disorder in youth
Neuroimaging difference between bipolar and unipolar depression
Neuroimaging in bipolar disorder and schizophrenia
How genetic research informs models of bipolar disorder
Genetic techniques and their application to bipolar disorder
General genetic findings in bipolar disorder
Genetics of bipolar disorder and schizophrenia
Mitochondrial genetics and bipolar disorder
Integration and future directions
Personalized medicine - can genetics and imaging inform treatment
Integration and consolidation - a neurophysiological model of bipolar disorder
Table of Contents provided by Publisher. All Rights Reserved.

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