Cardiovascular Genetics and Genomics for the Cardiologist

by ;
  • ISBN13:


  • ISBN10:


  • Edition: 1st
  • Format: eBook
  • Copyright: 2008-04-15
  • Publisher: Wiley-Blackwell

Note: Supplemental materials are not guaranteed with Rental or Used book purchases.

Purchase Benefits

  • Free Shipping On Orders Over $35!
    Your order must be $35 or more to qualify for free economy shipping. Bulk sales, PO's, Marketplace items, eBooks and apparel do not qualify for this offer.
  • Get Rewarded for Ordering Your Textbooks! Enroll Now
List Price: $206.87 Save up to $20.69
  • Rent Book $186.18
    Add to Cart Free Shipping


Supplemental Materials

What is included with this book?

  • The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any access cards, study guides, lab manuals, CDs, etc.
  • The Rental copy of this book is not guaranteed to include any supplemental materials. Typically, only the book itself is included. This is true even if the title states it includes any access cards, study guides, lab manuals, CDs, etc.


Until recently, a modest knowledge of genetics was more than adequate for the daily practice of clinical cardiology, but advances in genetics and genomics are changing cardiovascular medicine in fundamental ways. The identification of the genetic basis of several forms of dyslipidemia, hypertension, diabetes, cardiomyopathies, and vascular diseases signalled the new importance of genetics in clinical medicine.

In this timely volume, Drs. Dzau and Liew – both pioneers in the area – help cardiologists understand:
• how cardiovascular genetics may remodel the way cardiovascular medicine is practiced
• what material has immediate relevance to the practicing clinician
• how to incorporate genetics and genomics in your practice to ensure up-to-date patient care

The book opens with introductory chapters, then discusses:
• cardiovascular single gene disorders
• cardiovascular polygenic disorders
• therapies and applications

Outstanding contributors write on their areas of expertise, making Cardiovascular Genetics and Genomics for the Cardiologist both authoritative and comprehensive. If you want to gain a better appreciation of how genetics and genomics are already shaping current practice and may potentially revolutionize cardiology, look no further than this dependable reference.

Author Biography

Victor J. Dzau, MD
James B. Duke Professor of Medicine, Director, Mandel Center for Hypertension and Atherosclerosis Research; and Chancellor for Health Affairs, Duke University, Durham, USA

Choong-Chin Liew, PhD
Professor Emeritus, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; and (formerly) Visiting Professor of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA

Table of Contents




1 The gene in the twenty-first century.

Choong-Chin Liew, Victor J. Dzau.

Part I: Cardiovascular single gene disorders.

2 Monogenic hypercholesterolemia.

Ruth McPherson.

3 Hypertrophic cardiomyopathy.

Ali J. Marian.

4 Dilated cardiomyopathy and other cardiomyopathies.

Mitra Esfandiarei, Robert Yanagawa, Bruce M. McManus.

5 The long QT syndrome.

Sabina Kupershmidt, Kamilla Kelemen, Tadashi Nakajima.

Part II: Cardiovascular polygenic disorders.

6 Atherosclerosis.

Päivi Pajukanta, Kiat Tsong Tan, Choong-Chin Liew.

7 Heart failure.

Markus Meyer, Peter VanBuren.

8 The implications of genes on the pathogenesis, diagnosis and therapeutics of hypertension.

Kiat Tsong Tan, Choong-Chin Liew.

Part III: Therapies and applications.

9 Gene therapy for cardiovascular disease: inserting new genes, regulating the expression of native genes, and correcting genetic defects.

Ion S. Jovin, Frank J. Giordano.

10 Stem cell therapy for cardiovascular disease.

Emerson C. Perin, Guilherme V. Silva.

11 Pharmacogenetics and personalized medicine.

Julie A. Johnson, Issam Zineh.

12 The potential of blood-based gene profiling for disease assessment.

Steve Mohr, Choong-Chin Liew.


Colour plates

Rewards Program

Write a Review