Casarett & Doull's Essentials of Toxicology, Third Edition

by Klaassen, Curtis; Watkins, John

• ISBN13: 9780071847087
• ISBN10: 0071847081
• Edition: 3rd
• Format: Paperback
• Copyright: 2015-08-17
• Publisher: McGraw-Hill Education / Medical

Summary

Understand the essential principles of toxicology and how poisons affect the human body with this accessible and engaging summary

Casarett & Doull’s Essentials of Toxicology is an easy-to-absorb distillation of the major principles and concepts that were presented in depth in Casarett & Doull’s Toxicology: The Basic Science of Poisons, Eighth Edition, the field’s gold-standard text.

Presented in full color, the book concisely describes the science of toxicology, and includes important concepts from anatomy, physiology, and biochemistry to facilitate the understanding of the principles and mechanisms of toxicant action on specific organ systems. A summary of key points at the beginning and review questions at the end of each chapter help you study, understand, and memorize the material.

Reflecting the expertise of more than sixty renowned contributors, Casarett & Doull’s Essentials of Toxicology is logically divided into seven sections:

• General Principles of Toxicology
• Disposition of Toxicants
• Nonorgan-directed Toxicity
• Target Organ Toxicity
• Toxic Agents
• Environmental Toxicology
• Applications of Toxicology

Succinct and comprehensive, there is no better text for gaining an understanding of essential principles, toxicokinetics, how toxic effects are passed on to succeeding generations, how each body system responds to poisons, and the specific effects of a wide range of toxic agents than Casarett & Doull’s Essentials of Toxicology.

Table of Contents

UNIT 1

GENERAL PRINCIPLES OF TOXICOLOGY

1. History and Scope of Toxicology

2. Principles of Toxicology

3. Mechanisms of Toxicity

4. Risk Assessment

UNIT 2

DISPOSITION OF TOXICANTS

5. Absorption, Distribution,

and Excretion of Toxicants

6. Biotransformation of Xenobiotics

7. Toxicokinetics

UNIT 3

NONORGAN-DIRECTED

TOXICITY

8. Chemical Carcinogenesis

9. Genetic Toxicology

10. Developmental Toxicology

UNIT 4

TARGET ORGAN TOXICITY

11. Toxic Responses of the Blood

12. Toxic Responses of the Immune System

13. Toxic Responses of the Liver

14. Toxic Responses of the Kidney

15. Toxic Responses of the Respiratory System

16. Toxic Responses of the Nervous System

17. Toxic Responses of the Ocular

and Visual System

18. Toxic Responses of the Heart

and Vascular System

19. Toxic Responses of the Skin

20. Toxic Responses of the Reproductive System

21. Toxic Responses of the Endocrine System

UNIT 5

TOXIC AGENTS

22. Toxic Effects of Pesticides

23. Toxic Effects of Metals

24. Toxic Effects of Solvents and Vapors

25. Toxic Effects of Radiation

26. Toxic Effects of Terrestrial Animal

27. Toxic Effects of Plants, Fungi, and Algae

UNIT 6

ENVIRONMENTAL TOXICOLOGY

28. Air Pollution

29. Ecotoxicology

UNIT 7

APPLICATIONS OF TOXICOLOGY

30. Food Toxicology

31. Analytic/Forensic Toxicology

32. Clinical Toxicology

33. Occupational Toxicology