Cellular and Molecular Immunology

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  • Edition: 6th
  • Format: Paperback
  • Copyright: 2007-05-23
  • Publisher: Elsevier Science Health Science div
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An exceptionally lucid guide to the latest immunology concepts! Through five best-selling editions, readers worldwide have appreciated this book's in-depth yet straightforward, richly illustrated approach to this complex subject. Now, sweeping updates incorporate the latest discoveries about innate immunity, the organization of lymphoid organs, and many other cutting-edge topics. Plus, online access via STUDENT CONSULT makes this an even more powerful learning resource! Clearly explains the experimental observations that form the basis for the science of immunology at the molecular, cellular, and whole-organism levelsand the conclusions that can be drawn from those observations. Highlights the implications of immunologic science for the management of human disease, emphasizing the clinical relevance of the material. Innate immunity chapter has been increased and moved to the beginning of the book to reflect how this area is newly recognized as a critical part of immunology. New or material has been added on: - recognition of microbial products by cytoplasmic and membrane sensors - intricate organization of lymphoid tissues - functional heterogeneity of subsets of dendritic cells and lymphocytes - roles of regulatory cells and inhibitory pathways in immune regulation. Provides a wealth of excellent full-color photographs and illustrations that enable you to visualize immunologic processes quickly. Includes highlighted "take-home messages" that make it easy to review key information. Image Collection on Evolve

Table of Contents

Introduction to the Immune System
Properties and Overview of Immune Responsesp. 3
Innate Immunityp. 19
Cells and Tissues of the Adaptive Immune Systemp. 47
Recognition of Antigens
Antibodies and Antigensp. 75
The Major Histocompatibility Complexp. 97
Antigen Processing and Presentation to T Lymphocytesp. 113
Antigen Receptors and Accessory Molecules of T Lymphocytesp. 137
Maturation, Activation and Regulation of Lymphocytes
Lymphocyte Development and the Rearrangement and Expression of Antigen Receptor Genesp. 153
Activation of T Lymphocytesp. 189
B Cell Activation and Antibody Productionp. 215
Immunological Tolerancep. 243
Effector Mechanisms of Immune Responses
Cytokinesp. 267
Effector Mechanisms of Cell-Mediated Immunityp. 303
Effector Mechanisms of Humoral Immunityp. 321
The Immune System in Defense and Disease
Immunity to Microbesp. 351
Transplantation Immunologyp. 375
Immunity to Tumorsp. 397
Diseases Caused by Immune Responses: Hypersensitivity and Autoimmunityp. 419
Immediate Hypersensitivityp. 441
Congenital and Acquired Immunodeficienciesp. 463
Glossaryp. 489
Principal Features of Selected CD Moleculesp. 519
Laboratory Techniques Commonly Used in Immunologyp. 525
Indexp. 539
Table of Contents provided by Ingram. All Rights Reserved.

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