Clinical Drug Therapy : Rationales for Nursing Practice

by Abrams, Anne Collins; Pennington, Sandra Smith; Lammon, Carol Barnett

Edition:

8th

ISBN13:

9780781762632

ISBN10:

0781762634

Format:

Paperback

Pub. Date:

2/2/2006

Publisher(s):

LIPPINCOTT WILLIAMS & WILKINS

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Summary

This popular core nursing pharmacology textbook provides unique coverage of nursing interventions for drug therapy with related rationales. Highly praised for its organized and readable presentation, the text explains the "why" behind each nursing action and emphasizes how drugs work differently in different patients. New to the Eighth Edition are case studies integrated into each chapter with case-based questions that foster critical thinking. New Research Briefs summarize current research and its nursing implications. A new chapter covers drugs for obesity, and all nutrition products have been consolidated into one chapter. New NCLEX(R)-style questions appear at the end of each drug chapter.

SECTION 1 Foundations of Drug Therapy

(72)

Introduction to Pharmacology

(7)

A Message to Students

(1)

Pharmacology and Drug Therapy

(1)

Understanding Grouping and Naming of Drugs

(1)

Prescription and Nonprescription Drugs

(2)

Sources of Drugs

(1)

Drug Development and Approval

(2)

Pharmacoeconomics

(1)

Sources of Drug Information

(1)

Strategies for Studying Pharmacology

(2)

Basic Concepts and Processes

(21)

Introduction

(1)

Cellular Physiology

(2)

Drug Transport Through Cell Membranes

(1)

Pharmacokinetics

(5)

Pharmacodynamics

(1)

Variables That Affect Drug Actions

(7)

Adverse Effects of Drugs

(1)

Toxicology: Drug Overdose

(5)

Administering Medications

(19)

Introduction

(1)

General Principles of Accurate Drug Administration

(1)

Legal Responsibilities

(1)

Medication Errors

(1)

Medication Systems

(1)

Medication Orders

(1)

Drug Preparations and Dosage Forms

(2)

Calculating Drug Dosages

(2)

Routes of Administration

(12)

Nursing Process in Drug Therapy

(23)

Introduction

(1)

Nursing Process in Drug Therapy

(5)

Integrating Nursing Process, Critical Paths, and Drug Therapy

(6)

General Principles of Drug Therapy

(11)

SECTION 2 Drugs Affecting the Central Nervous System

(190)

Physiology of the Central Nervous System

(7)

Introduction

(1)

Basic Unit of the Central Nervous System: The Neuron

(1)

Neurotransmission

(3)

Major Components of the Central Nervous System

(2)

Drugs That Affect the Central Nervous System

(2)

Opioid Analgesics and Opioid Antagonists

(21)

Introduction

(1)

General Characteristics of Opioid Analgesics

(2)

Individual Drugs

(7)

Principles of Therapy

(11)

Analgesic--Antipyretic--Anti-Inflammatory and Related Drugs

103

(29)

Introduction

103

(1)

General Characteristics of Analgesic--Antipyretic--Anti-Inflammatory and Related Drugs

104

(5)

Classifications and Individual Drugs

109

(10)

Principles of Therapy

119

(13)

Antianxiety and Sedative-Hypnotic Drugs

132

(21)

Introduction

132

(3)

General Characteristics of Benzodiazepines

135

(3)

Individual Drugs

138

(4)

Principles of Therapy

142

(11)

Antipsychotic Drugs

153

(21)

Introduction

153

(1)

General Characteristics of Antipsychotic Drugs

154

(1)

Individual Drugs

155

(8)

Principles of Therapy

163

(11)

Antidepressants and Mood Stabilizers

174

(19)

Introduction

174

(2)

General Characteristics of Antidepressant Drugs

176

(1)

Types of Antidepressants and Individual Drugs

177

(5)

Principles of Therapy

182

(11)

Antiseizure Drugs

193

(21)

Introduction

193

(1)

General Characteristics of Antiseizure Drugs

194

(1)

Individual Drugs

195

(8)

Principles of Therapy

203

(11)

Antiparkinson Drugs

214

(13)

Introduction

214

(1)

General Characteristics of Antiparkinson Drugs

214

(2)

Individual Antiparkinson Drugs

216

(4)

Principles of Therapy

220

(7)

Skeletal Muscle Relaxants

227

(8)

Introduction

227

(1)

General Characteristics of Skeletal Muscle Relaxants

228

(1)

Individual Drugs

228

(3)

Principles of Therapy

231

(4)

Substance Abuse Disorders

235

(18)

Introduction

235

(2)

Central Nervous System Depressants

237

(5)

Central Nervous System Stimulants

242

(8)

Principles of Therapy

250

(3)

Central Nervous System Stimulants

253

(10)

Introduction

253

(1)

General Characteristics of Stimulants

254

(1)

Individual Drugs

254

(4)

Principles of Therapy

258

(5)

SECTION 3 Drugs Affecting the Autonomic Nervous System

263

(70)

Physiology of the Autonomic Nervous System

265

(7)

Introduction

265

(1)

Structure and Function of the Autonomic Nervous System

265

(6)

Characteristics of Autonomic Drugs

271

(1)

Adrenergic Drugs

272

(17)

Introduction

272

(1)

General Characteristics of Adrenergic Drugs

272

(3)

Individual Drugs

275

(4)

Principles of Therapy

279

(10)

Antiadrenergic Drugs

289

(18)

Introduction

289

(1)

General Characteristics of Antiadrenergic Drugs

289

(2)

Individual Drugs

291

(7)

Principles of Therapy

298

(9)

Cholinergic Drugs

307

(12)

Introduction

307

(1)

General Characteristics of Cholinergic Drugs

308

(1)

Individual Drugs

309

(3)

Principles of Therapy

312

(7)

Anticholinergic Drugs

319

(14)

Introduction

319

(1)

General Characteristics of Anticholinergic Drugs

319

(2)

Individual Drugs

321

(5)

Principles of Therapy

326

(7)

SECTION 4 Drugs Affecting the Endocrine System

333

(132)

Physiology of the Endocrine System

335

(4)

Introduction

335

(1)

Endocrine System--Nervous System Interactions

336

(1)

General Characteristics of Hormones

336

(2)

Use of Hormonal Drugs

338

(1)

Hypothalamic and Pituitary Hormones

339

(13)

Introduction

339

(1)

Types of Hormones

339

(2)

Individual Drugs

341

(6)

Principles of Therapy

347

(5)

Corticosteroids

352

(21)

Introduction

352

(3)

General Characteristics of Exogenous Corticosteroids

355

(8)

Principles of Therapy

363

(10)

Thyroid and Antithyroid Drugs

373

(14)

Introduction

373

(1)

General Characteristics of Thyroid and Antithyroid Drugs

374

(2)

Individual Drugs

376

(3)

Principles of Therapy

379

(8)

Hormones That Regulate Calcium and Bone Metabolism

387

(17)

Introduction

387

(3)

Individual Drugs

390

(6)

Principles of Therapy

396

(8)

Antidiabetic Drugs

404

(32)

Introduction

404

(3)

Hypoglycemic Drugs

407

(12)

Principles of Therapy

419

(17)

Estrogens, Progestins, and Hormonal Contraceptives

436

(19)

Introduction

436

(2)

General Characteristics of Estrogens, Progestins, and Hormonal Contraceptives

438

(2)

Individual Drugs

440

(7)

Principles of Therapy

447

(8)

Androgens and Anabolic Steroids

455

(10)

Introduction

455

(2)

General Characteristics of Androgens and Anabolic Steroids Used As Drugs

457

(1)

Individual Drugs

458

(2)

Principles of Therapy

460

(5)

SECTION 5 Drugs Used to Treat Infections

465

(154)

General Characteristics of Antimicrobial Drugs

467

(18)

Introduction

467

(1)

Microorganisms and Infections

467

(7)

Characteristics of Antimicrobial Drugs

474

(2)

Principles of Therapy

476

(9)

Beta-Lactam Antibacterials: Penicillins, Cephalosporins, and Other Drugs

485

(19)

Introduction

485

(1)

Penicillins

485

(4)

Cephalosporins

489

(2)

Carbapenems

491

(3)

Monobactam

494

(1)

Principles of Therapy

495

(9)

Aminoglycosides and Fluoroquinolones

504

(11)

Introduction

504

(1)

Aminoglycosides

504

(3)

Fluoroquinolones

507

(2)

Principles of Therapy

509

(6)

Tetracyclines, Sulfonamides, and Urinary Agents

515

(13)

Introduction

515

(7)

Principles of Therapy

522

(6)

Macrolides, Ketolides, and Miscellaneous Antibacterials

528

(14)

Introduction

528

(1)

Macrolides and Ketolides

528

(2)

Miscellaneous Antibacterial Drugs

530

(3)

Principles of Therapy

533

(9)

Drugs for Tuberculosis and Mycobacterium avium Complex (MAC) Disease

542

(18)

Introduction

542

(2)

Antitubercular Drugs

544

(6)

Treatment of Active Tuberculosis

550

(1)

Mycobacterium avium Complex Disease

550

(2)

Principles of Therapy

552

(8)

Antiviral Drugs

560

(22)

Introduction

560

(2)

Antiviral Drugs

562

(9)

Principles of Therapy

571

(11)

Antifungal Drugs

582

(21)

Introduction

582

(1)

Antifungal Drugs

583

(12)

Principles of Therapy

595

(8)

Antiparasitics

603

(16)

Introduction

603

(3)

Antiparasitic Drugs

606

(8)

Principles of Therapy

614

(5)

SECTION 6 Drugs Affecting Hematopoiesis and the Immune System

619

(104)

Physiology of the Hematopoietic and Immune Systems

621

(12)

Introduction

621

(1)

Hematopoietic Cytokines

621

(3)

Overview of Body Defense Mechanisms

624

(1)

Immunity

624

(2)

Immune Cells

626

(3)

Immune System Cytokines

629

(1)

Client-Related Factors That Influence Immune Function

629

(2)

Immune Disorders

631

(1)

Drugs That Alter Hematopoietic and Immune Responses

632

(1)

Immunizing Agents

633

(18)

Introduction

633

(1)

General Characteristics of Immunizing Agents

634

(1)

Individual Immunizing Agents

634

(10)

Principles of Therapy

644

(7)

Hematopoietic and Immunostimulant Drugs

651

(14)

Introduction

651

(1)

General Characteristics of Hematopoietic and Immunostimulant Drugs

651

(4)

Classifications and Individual Drugs

655

(3)

Principles of Therapy

658

(7)

Immunosuppressants

665

(26)

Introduction

665

(3)

Classifications and Individual Drugs

668

(8)

Principles of Therapy

676

(15)

Drugs Used in Oncologic Disorders

691

(32)

Introduction

691

(3)

Traditional Cytotoxic Antineoplastic Drugs

694

(5)

Biologic Targeted Antineoplastic Drugs

699

(3)

Antineoplastic Hormone Inhibitor Drugs

702

(3)

Cytoprotectant Drugs

705

(4)

Principles of Therapy

709

(14)

SECTION 7 Drugs Affecting the Respiratory System

723

(48)

Physiology of the Respiratory System

725

(4)

Overview of the Respiratory System

725

(2)

Disorders of the Respiratory System

727

(1)

Drug Therapy

727

(2)

Drugs for Asthma and Other Bronchoconstrictive Disorders

729

(18)

Introduction

729

(3)

Bronchodilators

732

(3)

Anti-Inflammatory Agents

735

(4)

Principles of Therapy

739

(8)

Antihistamines and Allergic Disorders

747

(13)

Introduction

747

(3)

General Characteristics of Antihistamines

750

(3)

Classifications and Individual Drugs

753

(2)

Principles of Therapy

755

(5)

Nasal Decongestants, Antitussives, and Cold Remedies

760

(11)

Introduction

760

(1)

General Characteristics of Drugs Used in/for Respiratory Disorders

761

(1)

Individual Drugs

762

(4)

Principles of Therapy

766

(5)

SECTION 8 Drugs Affecting the Cardiovascular System

771

(140)

Physiology of the Cardiovascular System

773

(4)

Introduction

773

(1)

Heart

773

(1)

Blood Vessels

774

(1)

Blood

775

(1)

Cardiovascular Disorders

776

(1)

Drug Therapy Used for Cardiovascular Disorders

776

(1)

Drug Therapy for Heart Failure

777

(17)

Introduction

777

(1)

Inotropes

778

(5)

Human B-Type Natriuretic Peptide (Nesiritide)

783

(1)

Endothelin Receptor Antagonists (Bosentan)

784

(1)

Principles of Therapy

785

(9)

Antidysrhythmic Drugs

794

(20)

Introduction

794

(2)

General Characteristics of Antidysrhythmic Drugs

796

(1)

Classifications and Individual Drugs

796

(11)

Principles of Therapy

807

(7)

Antianginal Drugs

814

(15)

Introduction

814

(3)

Antianginal Drugs: Classifications and Individual Drugs

817

(6)

Principles of Therapy

823

(6)

Drugs Used in Hypotension and Shock

829

(9)

Introduction

829

(1)

General Characteristics of Antishock Drugs

830

(1)

Individual Drugs

830

(3)

Principles of Therapy

833

(5)

Antihypertensive Drugs

838

(23)

Introduction

838

(4)

Antihypertensives: Classifications and Individual Drugs

842

(9)

Principles of Therapy

851

(10)

Diuretics

861

(15)

Introduction

861

(2)

General Characteristics of Diuretic Drugs

863

(2)

Types of Diuretics and Individual Drugs

865

(3)

Principles of Therapy

868

(8)

Drugs That Affect Blood Coagulation

876

(21)

Introduction

876

(3)

Drugs Used in Thrombotic and Thromboembolic Disorders: Classifications and Individual Drugs

879

(9)

Principles of Therapy

888

(9)

Drugs for Dyslipidemia

897

(14)

Introduction

897

(3)

General Characteristics of Drugs Used for Management of Dyslipidemia

900

(1)

Dyslipidemic Drugs: Classifications and Individual Drugs

901

(4)

Principles of Therapy

905

(6)

SECTION 9 Drugs Affecting the Digestive System

911

(110)

Physiology of the Digestive System

913

(4)

Introduction

913

(1)

Structures of the Digestive System

913

(2)

Secretions of the Digestive System

915

(1)

Effects of Drugs on the Digestive System

916

(1)

Nutritional Support Products, Vitamins, and Mineral-Electrolytes

917

(35)

Introduction

917

(1)

Nutritional Deficiency States

917

(1)

Nutritional Products

918

(7)

Agents Used in Mineral-Electrolyte Imbalances

925

(10)

Principles of Therapy

935

(17)

Drugs to Aid Weight Management

952

(18)

Introduction

952

(5)

General Characteristics of Drugs for Obesity

957

(1)

Individual Drugs

957

(3)

Principles of Therapy

960

(10)

Drugs Used for Peptic Ulcer and Acid Reflux Disorders

970

(17)

Introduction

970

(2)

Classifications and Individual Drugs

972

(8)

Principles of Therapy

980

(7)

Laxatives and Cathartics

987

(10)

Introduction

987

(1)

General Characteristics of Laxatives and Cathartics

988

(1)

Classifications and Individual Drugs

988

(4)

Principles of Therapy

992

(5)

Antidiarrheals

997

(13)

Introduction

997

(1)

Characteristics, Classifications, and Individual Antidiarrheal Drugs

998

(6)

Principles of Therapy

1004

(6)

Antiemetics

1010

(11)

Introduction

1010

(1)

General Characteristics of Antiemetic Drugs

1011

(1)

Classifications and Individual Drugs

1011

(4)

Principles of Therapy

1015

(6)

SECTION 10 Drugs Used in Special Conditions

1021

(58)

Drugs Used in Ophthalmic Conditions

1023

(16)

Introduction

1023

(1)

Ophthalmic Drug Therapy

1024

(8)

Principles of Therapy

1032

(7)

Drugs Used in Dermatologic Conditions

1039

(18)

Introduction

1039

(3)

Dermatologic Drug Therapy

1042

(7)

Principles of Therapy

1049

(8)

Drug Use During Pregnancy and Lactation

1057

(22)

Introduction

1057

(1)

Pregnancy

1057

(2)

Fetal Therapeutics

1059

(1)

Maternal Therapeutics

1059

(10)

Drugs That Alter Uterine Motility

1069

(2)

Drugs Used During Labor and Delivery at Term

1071

(1)

Neonatal Therapeutics

1072

(1)

Principles of Therapy

1073

(6)

Appendix A Recently Approved and Miscellaneous Drugs

1079

(3)

Appendix B The International System of Units

1082

(1)

Appendix C Serum Drug Concentrations

1083

(1)

Appendix D Canadian Drug Laws and Standards

1084

(3)

Appendix E Canadian Drug Names

1087

(8)

Appendix F Anesthetics, Adjunctive Drugs, and Nursing Considerations

1095

(6)

Index

1101

Clinical Drug Therapy : Rationales for Nursing Practice

9780781762632

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