Clinical Magnetoencephalography and Magnetic Source Imaging

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  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2009-09-14
  • Publisher: Cambridge University Press
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Supplemental Materials

What is included with this book?


This is the first volume to explore the field of clinical magnetoencephalography (MEG) and magnetic source imaging (MSI), the techniques measuring the magnetic fields generated by neuronal activity in the brain. Describing the empirical knowledge gained during the last two decades, this book will serve as a basis for the training of clinicians and scientists entering this new and exciting field. The book covers the methods for recording MEG and performing MSI in a clinical setting and includes practical examples of data collection and analysis. It explains why MEG should be used in the evaluation and treatment of patients being considered for epilepsy surgery, concluding with a section describing the potential for future applications of these methods. This is essential reading for graduate students in clinical neuroscience, residents in neurology and psychiatry, neuroradiology and neurosurgery, specialists in neurophysiology and epilepsy, and clinicians in a wide range of related brain sciences.

Author Biography

Andrew C. Papanicolaou is Professor, Department of Pediatrics and Departments of Neurology and Neurosurgery, the University of Texas Medical School at Houston, Houston, Texas, USA.

Table of Contents

Contributorsp. viii
Prefacep. xi
The method
Basic conceptsp. 3
The nature and origin of magnetic signalsp. 7
Recording the magnetic fluxp. 13
Overview of MSI using the single equivalent current dipole (ECD) model as an examplep. 23
The fundamental problems of MSIp. 26
Head modelsp. 29
Source models-discrete source modelsp. 34
Source models-distributed source modelsp. 40
Source models-beamformersp. 44
Pragmatic features of the clinical use of MEG/MSIp. 47
Referencesp. 51
Spontaneous brain activity
MEG recordings of spontaneous brain activity - general considerationsp. 59
Normal spontaneous MEG-frequently encountered artifactsp. 63
Spontaneous MEG morphologyp. 68
Abnormal spontaneous MEGp. 75
Contributions of MEG to the surgical management of epilepsy - general considerationsp. 83
MEG investigations in lesional epilepsiesp. 88
MEG investigations in nonlesional epilepsiesp. 90
Pediatric nonlesional epilepsy surgeryp. 92
Referencesp. 102
Evoked magnetic fields
Recording evoked magnetic fields (EMFs)p. 111
Somatosensory evoked fields (SEFs)p. 118
Movement-related magnetic fields (MRFs) - motor evoked fields (MEFs)p. 128
Auditory evoked magnetic fields (AEFs)p. 134
Visual evoked magnetic fields (VEFs)p. 138
Language-related brain magnetic fields (LRFs)p. 144
Alternative techniques for evoked magnetic field data-future directionsp. 157
Referencesp. 159
Postscript: Future applications of clinical MEG
Overviewp. 173
Normal aging and neurodegenerative disordersp. 174
Neurodevelopmental disordersp. 178
Psychiatric disordersp. 183
Neurological disordersp. 186
Functional reorganizationp. 190
Referencesp. 192
Indexp. 200
Table of Contents provided by Ingram. All Rights Reserved.

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