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9780443066290

Clinical Oncology

by
  • ISBN13:

    9780443066290

  • ISBN10:

    0443066299

  • Edition: 3rd
  • Format: Hardcover
  • Copyright: 2004-06-11
  • Publisher: Churchill Livingstone

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Supplemental Materials

What is included with this book?

Summary

This completely revised 3rd Edition provides readers with an easy-to-use, comprehensive reference that features a clinical perspective balanced with relevant basic science. Readers will find the latest developments in basic science, pathology, diagnosis, management, outcomes, rehabilitation, and prevention. The addition of basic science editor Michael B. Kastan, MD, PhD ensures complete coverage of essential scientific information, including molecular tools in cancer research, cellular microenvironment, stem cells in cancer susceptibility genes, and more. Plus, a new templated, four-color design with highlighted boxes and algorithms offers easy access to pertinent information. Features the addition of basic science editor Michael B. Kastan, MD, PhD, ensuring complete coverage of essential scientific topics. Discusses the latest advances, including the most current developments in stem cell therapies and new approaches to innovations in diagnosis. Provides new information on geriatric oncology, as well as new chapters on pathology, imaging, and molecularly targeted therapies. Covers the hottest topics in the field, such as molecular tools in cancer research, cellular microenvironment, stem cells in cancer susceptibility genes, and more. Presents a multidisciplinary approach to disease chapters, including a pathologist, radiation oncologist, medical oncologist, and surgeon. Includes a CD-ROM image bank of the text's illustrations downloadable into PowerPoint® presentations. Offers a user-friendly layout with standard chapter templates summary boxes at the beginning of each chapter management "opinion" boxes a new full-color design and over 1,000 full-color illustrations, diagrams, and algorithms. And much more!

Table of Contents

Science of Clinical Oncologyp. 1
Biology and Cancer
Molecular Tools in Cancer Researchp. 3
Intracellular Signalingp. 19
The Cellular Microenvironmentp. 47
Biology of Cancer Metastasisp. 59
Control of the Cell Cyclep. 81
Cell Life and Cell Deathp. 101
Immunology and Cancerp. 113
Stem Cells, Cell Differentiation, and Cancerp. 139
Vascular and Interstitial Biology of Tumorsp. 153
The Genesis of Cancer
Environmental Factorsp. 173
DNA Damage Response Pathways and Cancerp. 191
Viruses and Human Cancerp. 207
Genetic Factors: Hereditary Cancer Predisposition Syndromesp. 227
Genetic Factors: Finding Cancer Susceptibility Genesp. 253
Progressing from Gene Mutations to Cancerp. 269
Immunodeficiency and Cancerp. 287
Diagnosing Cancer
Pathology and Laboratory Medicinep. 299
Surgical Pathologyp. 300
Flow Cytometry in Oncologic Diagnosisp. 305
Cytogeneticsp. 311
Molecular Diagnosticsp. 320
Clinical Chemistry: Tumor Markersp. 329
Imagingp. 341
Preventing and Treating Cancer
Biostatistics for Clinical Trialsp. 365
Structures Supporting Cancer Clinical Trialsp. 383
Economic Analysis of Cancer Treatmentp. 395
Epidemiology and Population Sciencesp. 407
Cancer Prevention, Screening, and Early Detectionp. 425
Smoking Cessation: Current Treatments and Future Directionsp. 473
Chemotherapyp. 483
The Basics of Radiation Therapyp. 537
Surgical Interventions in Cancerp. 579
Bone Marrow Transplantationp. 591
Gene Therapy in Oncologyp. 603
The Present and Future of Molecularly Targeted Therapyp. 623
Photodynamic Therapyp. 639
Therapeutic Antibodies and Immunologic Conjugatesp. 661
Cancer Vaccinesp. 677
Complementary and Alternative Medicinep. 695
Problems Common to Cancer and Its Therapyp. 713
Symptom Management and Palliative Care
Cancer Painp. 715
Rehabilitation of the Patient with Cancerp. 731
Cachexiap. 749
Nausea and Vomitingp. 759
Oral Complicationsp. 775
Alopecia and Cutaneous Complicationsp. 793
Lymphedemap. 817
Fatiguep. 835
Caring for Patients at the End of Lifep. 847
Hematologic Problems
Disorders of Blood Cell Production in Clinical Oncologyp. 861
Diagnosis, Treatment, and Prevention of Cancer-Related Venous Thrombosisp. 891
Infections
Fever in the Neutropenic Cancer Patientp. 925
Infection in the Severely Immunocompromised Patientp. 941
Metabolic and Paraneoplastic Syndromes
Hypercalcemiap. 957
Hyponatremiap. 973
Tumor Lysis Syndromep. 987
Paraneoplastic Neurologic Syndromesp. 993
Surgical Problems
Establishing and Maintaining Vascular Accessp. 1007
Acute Abdomen, Bowel Obstruction, and Fistulap. 1025
Local Effects of Cancer and Its Metastasis
Superior Vena Cava Syndromep. 1047
Spinal Cord Compressionp. 1063
Brain Metastases and Carcinomatous Meningitisp. 1073
Bone Metastasesp. 1091
Lung Metastasesp. 1129
Liver Metastasesp. 1141
Effusionsp. 1179
Neurologic Complicationsp. 1213
Pulmonary Complications of Anticancer Treatmentp. 1237
Cardiac Effects of Cancer Therapyp. 1251
Reproductive Complicationsp. 1269
Endocrine Complicationsp. 1287
Second Malignant Neoplasmsp. 1297
Special Issues
Cancer in the Elderly: Biology, Prevention, and Treatmentp. 1317
Special Issues in Pregnancyp. 1331
Specific Malignanciesp. 1345
Cancer of the Central Nervous Systemp. 1347
Eye, Orbit, and Adnexal Structuresp. 1433
Cancer of the Head and Neckp. 1497
Melanomap. 1561
Nonmelanoma Skin Cancers: Basal Cell and Squamous Cell Carcinomasp. 1589
Cancer of the Endocrine Systemp. 1611
Cancer of the Lung: NSCLC and SCLCp. 1649
Tumors of the Pleura and Mediastinump. 1745
Cancer of the Esophagusp. 1787
Cancer of the Stomachp. 1819
Cancer of the Small Bowelp. 1863
Colon Cancerp. 1877
Cancer of the Rectump. 1943
Cancer of the Anal Canalp. 1967
Liver and Bile Duct Cancerp. 1981
Carcinoma of the Pancreasp. 2015
Kidney and Ureterp. 2035
Carcinoma of the Bladderp. 2059
Prostate Cancerp. 2085
Cancer of the Penis and Urethrap. 2149
Testicular Cancerp. 2175
Cancers of the Cervix, Vagina, and Vulvap. 2217
Cancer of the Uterusp. 2273
Ovaries and Fallopian Tubesp. 2311
Gestational Trophoblastic Diseasep. 2347
Cancer of the Breastp. 2369
Sarcomas of Bonep. 2471
Sarcomas of Soft Tissuep. 2573
Unknown Primary Cancerp. 2627
HIV-Associated Malignanciesp. 2647
Pediatric Solid Tumorsp. 2661
The World Health Organization Classification of Hematologic Malignanciesp. 2723
Childhood Leukemiap. 2731
Childhood Lymphomap. 2765
Acute Lymphoid Leukemia in Adultsp. 2793
Acute Myeloid Leukemia in Adultsp. 2825
The Myelodysplastic Syndromesp. 2849
Chronic Myeolo-proliferative Diseasesp. 2883
Chronic Myeloid Leukemiap. 2899
Chronic Lymphoid Leukemiasp. 2921
Hairy Cell Leukemiap. 2941
Multiple Myeloma and Related Disordersp. 2955
Hodgkin's Lymphomap. 2985
Non-Hodgkin's Lymphomap. 3015
Cutaneous T-Cell Lymphoma and Cutaneous B-Cell Lymphomap. 3077
Adult T-Cell Leukemia-Lymphomap. 3109
Indexp. 3131
Table of Contents provided by Rittenhouse. All Rights Reserved.

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