Computational Methods for Protein Structure Prediction And Modeling

by Xu, Ying; Xu, Dong; Liang, Jie

• ISBN13: 9780387333212
• ISBN10: 0387333215
• Format: Hardcover
• Copyright: 2006-12-30
• Publisher: Springer Verlag

Summary

Volume two of this two volume sequence focuses on protein structure prediction and includes protein threading, De novo methods, applications to membrane proteins and protein complexes, structure-based drug design, as well as structure prediction as a systems problem. A series of appendices review the biological and chemical basics related to protein structure, computer science for structural informatics, and prerequisite mathematics and statistics.

Author Biography

Dr. Ying Xu is Regents-GRA Eminent Scholar and Professor at the University of Georgia.  Dr. Dong Xu is the Director of the Digital Biology Laboratory at the University of Missouri-Columbia.  Dr. Jie Liang is the Director for the Center for Bioinformatics at the University of Illinois at Chicago.

Table of Contents

Contributors	p. xvii
Protein Structure Prediction by Protein Threading	p. 1
De Novo Protein Structure Prediction	p. 43
Structure Prediction of Membrane Proteins	p. 65
Structure Prediction of Protein Complexes	p. 109
Structure-Based Drug Design	p. 135
Protein Structure Prediction as a Systems Problem	p. 177
Resources and Infrastructure for Structural Bioinformatics	p. 207
Biological and Chemical Basics Related to Protein Structures	p. 229
Computer Science for Structural Informatics	p. 241
Physical and Chemical Basis for Structural Bioinformatics	p. 267
Mathematics and Statistics for Studying Protein Structures	p. 299
Index	p. 317
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