Counseling about Cancer : Strategies for Genetic Counseling

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  • Edition: 3rd
  • Format: Paperback
  • Copyright: 2011-12-06
  • Publisher: Wiley-Blackwell

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Important scientific discoveries and ever-changing guidelines for how to identify and manage patients with hereditary cancer syndromes are constantly evolving. This Third Edition of Counseling About Cancer is completely updated and expanded to feature five entirely new chapters on breast cancer, colon cancer, other solid tumors, clients and families, and genetic test results and follow-up. This is the only reference and clinical book on the market for cancer genetics counselors and other healthcare providers who must quickly assimilate complex and ever-changing data on the hereditary risk for cancer.

Table of Contents

Forewordp. xi
Prefacep. xiii
Acknowledgmentsp. xv
Cancer Epidemiologyp. 1
Cancer Statisticsp. 1
Cancer Etiologyp. 10
Case Examplesp. 18
Further Readingp. 21
Cancer Detection and Treatmentp. 23
The Diagnosis of Cancerp. 23
Tumor Classificationp. 31
Cancer Treatmentp. 37
Further Readingp. 45
Cancer Biologyp. 47
The Malignant Cellp. 47
Carcinogenesisp. 52
Oncogenesp. 59
Tumor Suppressor Genesp. 64
Epigenetic Mechanismsp. 70
Further Readingp. 73
Hereditary Cancer Syndromesp. 75
Ataxia Telangiectasiap. 75
Autoimmune Lymphoproliferative Syndrome (Also Canale-Smith Syndrome)p. 77
Beckwith-Wiedemann Syndrome (Also Exomphalos Macroglossia Gigantism [EMG] Syndrome)p. 78
Birt-Hogg-Dubé Syndromep. 80
Bloom Syndromep. 82
Blue Rubber Bleb Nevus Syndrome (Also Termed Bean Syndrome)p. 83
Breast-Ovarian Cancer Syndrome, Hereditaryp. 84
Carney Complex, Types I and II (Includes NAME Syndrome and LAMB Syndrome)p. 87
Diamond-Blackfan Anemiap. 89
Familial Adenomatous Polyposis (Also Attenuated FAP, Gardner's Syndrome, Turcot Syndrome, and Hereditary Desmoid Disease)p. 90
Fanconi Anemiap. 93
Gastric Cancer, Hereditary Diffusep. 95
Gastrointestinal Stromal Tumor, Familial (Also Multiple GI Autonomic Nerve Tumors)p. 97
Juvenile Polyposis (Includes Hereditary Mixed Polyposis)p. 98
Leiomyomatosis Renal Cell Cancer, Hereditaryp. 100
Li-Fraumeni Syndromep. 101
Lynch Syndrome (Also Termed HNPCC)p. 105
Melanoma, Cutaneous Malignant (Includes Familial Atypical Mole-Malignant Melanoma Syndrome, Dysplastic Nevus Syndrome, and Melanoma-Astrocytoma Syndrome)p. 109
Multiple Endocrine Neoplasia, Type 1 (Also Wermer Syndrome)p. 111
Multiple Endocrine Neoplasia, Type 2 (Also Sipple Syndrome, Familial Medullary Thyroid Carcinoma Syndrome)p. 113
MYH-Associated Polyposisp. 115
Neuroblastoma, Familialp. 116
Neurofibromatosis, Type 1 (Also von Recklinghausen Disease)p. 118
Neurofibromatosis, Type 2p. 119
Nevoid Basal Cell Carcinoma Syndrome (Also Gorlin Syndrome, Basal Cell Nevus Syndrome)p. 121
Paraganglioma-Pheochromocytoma Syndrome, Hereditary (Including Carney-Stratakis Syndrome)p. 123
Peutz-Jeghers Syndromep. 125
PTEN Hamartoma Syndrome (PHS) (Also Cowden Syndrome; Includes Bannayan-Riley-Ruvalcaba Syndrome and Proteus Syndrome)p. 127
Renal Cell Carcinoma, Hereditary Papillaryp. 130
Retinoblastoma, Hereditaryp. 131
Rothmund-Thomson Syndromep. 133
Tuberous Sclerosis Complex (TSC)p. 134
Von Hippel Lindau Syndromep. 137
Werner Syndrome (Also Termed Progeria of the Adult)p. 139
Wilms Tumor, Familial (Includes Denys-Drash Syndrome, Frasier Syndrome, WAGR Syndrome)p. 141
Xeroderma Pigmentosum (Includes XP/CS Complex, XP Variant)p. 143
Further Readingp. 145
All About Breast Cancerp. 151
Overview of Breast Cancerp. 151
Breast Cancer Management: Screening, Diagnosis, and Treatmentp. 162
Breast Cancer Syndromesp. 171
Further Readingp. 184
All About Colorectal Cancerp. 187
Overview of Colorectal Cancerp. 187
CRC Management: Screening, Diagnosis, and Treatmentp. 199
CRC Syndromesp. 207
Further Readingp. 218
Collecting and Interpreting Cancer Historiesp. 221
Collecting a Cancer Historyp. 221
Challenges to Collecting an Accurate Historyp. 242
Interpreting a Cancer Historyp. 246
Case Examplesp. 255
Further Readingp. 266
Cancer Risk Communicationp. 267
Genetic Counseling and Risk Perceptionp. 267
The Communication of Riskp. 278
Counseling Clients at various Risksp. 289
Case Examplesp. 298
Further Readingp. 306
Genetic Testing and Counselingp. 309
The Logistics of Arranging Testsp. 309
Pretest Counselingp. 325
Results Disclosure and Follow-Upp. 337
Case Examplesp. 346
Further Readingp. 356
Psychosocial Aspects of Cancer Counselingp. 357
The Psychosocial Features of Clientsp. 357
Making a Psychosocial Assessmentp. 379
Providing Additional Emotional Supportp. 394
Case Examplesp. 400
Further Readingp. 407
Ethical Issues in Cancer Genetic Counselingp. 409
Bioethical Principles and Guidelinesp. 409
Strategies for Resolving Ethical Dilemmasp. 423
Types of Ethical Dilemmas in Cancer Genetic Counselingp. 431
Issues of Justicep. 442
Further Readingp. 443
Specific Tumor Types and Associated Syndromesp. 445
Review of Basic Pedigree Symbolsp. 457
Indexp. 459
Table of Contents provided by Ingram. All Rights Reserved.

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