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9781573312004

Cutaneous Neuroimmunomodulation : The Proopiomelanocortin System

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  • ISBN13:

    9781573312004

  • ISBN10:

    1573312002

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 1999-12-01
  • Publisher: New York Academy of Sciences

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Table of Contents

The Proopiomelanocortin System in Cutaneous Neuroimmunomodulation: An Introductory Overview xi
Thomas A. Luger
Ralf Paus
Andrzej Slominski
James Lipton
Part I. Extracutaneous Proopiomelanocortin Biology
The Proopiomelanocortin System
1(21)
Mac E. Hadley
Carrie Haskell-Luevano
POMC--Derived Peptides and Their Biological Action
22(19)
Samuel Solomon
The Pituitary-Skin Connection in Amphibians: Reciprocal Regulation of Melanotrope Cells and Dermal Melanocytes
41(16)
H. Vaudry
N. Chartrel
L. Desrues L. Galas
S. Kikuyama
A. Mor
P. Nicolas
M.C. Tonon
The Subtilisin/Kexin Family of Precursor Convertases: Emphasis on PCI, PC2/ 7B2, POMC, and the Novel Enzyme SKI-1
57(18)
Nabil G. Seidah
Suzanne Benjannet
Josee Hamelin
Aida M. Mamarbachi
Ajoy Basak
Jadwiga Marcinkiewicz
Majambu Mbikay
Michel Chretien
Mieczyslaw Marcinkiewicz
The Role of Melanocortins in Adipocyte Function
75(10)
Bruce A. Boston
An Immunocytochemical Approach to the Study of β-Endorphin Production in Human Keratinocytes using Confocal Microscopy
85(15)
Susana B. Zanello
David M. Jackson
Michael F. Holick
Part II. The Melanocortin Receptors
UV Light and MSH Receptors
100(17)
Ashok K. Chakraborty
Yoko Funasaka
Andrzej Slominski
Jean Bolognia
Stefano Sodi
Masamitsu Ichihashi
John M. Pawelek
The Melanocortin-1 Receptor and Human Pigmentation
117(17)
Zalfa Abdel-Malek
Itaru Suzuki
Akihiro Tada
Sungbin Im
Can Akcali
Genetic Studies of the Human Melanocortin-1 Receptor
134(9)
Jonathan L. Rees
Mark Birch-Machin
Niamh Flanagan
Eugene Healy, Sion Phillips
Carole Todd
Molecular Pharmacology of Agouti Protein in Vitro and in Vivo
143(10)
Gregory S. Barsh
Michael M. Ollmann
Brent D. Wilson
Kimberly A. Miller
Teresa M. Gunn
Synthetic Melanocortin Receptor Agonists and Antagonists
153(8)
Michael R. Lerner
Proopiomelanocortin and the Immune-Neuroendocrine Connection
161(12)
J. Edwin Blalock
Part III. Proopiomelanocortin and the Skin Immune System: Modulation of the Immune Response
Mechanisms of Antinflammatory Action of α-MSH Peptides: In Vivo and in Vitro Evidence
173(10)
J.M. Lipton
H. Zhao
T. Ichiyama
G.S. Barsh
A. Catania
α-MSH in Systemic Inflammation: Central and Peripheral Actions
183(5)
Anna Catania
Rene Delgado
Lorena Airaghi
MariaGrazia Cutul
Letizia Garofalo
Andrea Carlin
Maria Teresa Demitri
James M. Lipton
Human Peripheral Blood-Derived Dendritic Cells Express Functional Melanocortin Receptor MC-1R
188(8)
E. Becher
K. Mahnke
T. Brzoska
D.-H. Kalden, S. Grabbe
T.A. Luger
Neural Influences on Induction of Contact Hypersensitivity
196(13)
J. Wayne Streilein
Pascale Alard
Hironori Nizeki
Role of Epidermal Cell-Derived α-Melanocyte Stimulating Hormone in Ultraviolet Light Mediated Local Immunosuppression
209(8)
T.A. Luger
T. Schwarz
H. Kalden
T. Scholzen
A. Schwarz
T. Brzoska
Part IV. Modulation of Skin Physiology by Proopiomelanocortin Products
α-MSH and the Regulation of Melanocyte Function
217(13)
Anthony J. Thody
Molecular Basis of the α-MSH/IL-I Antagonism
230(9)
T. Brzoska
D.-H. Kalden
T. Scholzen
T.A. Luger
Expression of Functional Melanocortin Receptors and Proopiomelanocortin Peptides Human Dermal Microvascular Endothelial Cells
239(15)
Thomas E. Scholzen
Thomas Brzoska
Dirk-Henner Kalden
Mechthild Hartmeyer
Michaela Fastrich
Thomas A. Luger
Cheryl A. Armstrong
John C. Ansel
Mechanisms of the Antiinflammatory Effects of α-MSH: Role of Transcription Factor NF-κB and Adhesion Molecule Expression
254(8)
D.-H. Kalden
T. Scholzen
T. Brzoska
T.A. Luger
POMC and Fibroblast Biology
262(6)
Torello Lotti
Patrizia Teofoli
Beatrice Bianchi
Alain Mauviel
The Role of Proopiomelanocortin-Derived Peptides in Skin Fibroblast and Mast Cell Functions
268(9)
Patrizia Teofoli
Alessandra Frezzolini
Pietro Puddu
Ornella De Pita
Alain Mauviel
Torello Lotti
Alpha-Melanocyte-Stimulating Hormone Modulates Activation of NF-κB and AP-1 and Secretion of Interleukin-8 in Human Dermal Fibroblasts
277(10)
Markus Bohm
Ursula Schulte
Henner Kalden
T.A. Luger
Part V. Corticotropin-Releasing Hormone-Proopiomelanocortin Interactions
Cutaneous Expression of CRH and CRH-R: Is There a ``Skin Stress Response System?''
287(25)
Andrzej T. Slominski
Vladimir Botchkarev
Mashkoor Choudhry
Nadeem Fazal
Klaus Fechner
Jens Furkert
Eberhart Krause
Birgit Roloff
Mohammad Sayeed
Edward Wei
Blazej Zbytek
Josef Zipper
Jacobo Wortsman
Ralf Paus
Corticotropin Releasing Factor Receptors and Their Ligand Family
312(17)
Marilyn H. Perrin
Mylie W. Vale
Part VI. Proopiomelanocortin-Peptides-Clinical Relevance
α-MSH Can Control the Essential Cofactor 6-Tetrahydrobiopterin in Melanogenesis
329(13)
Karin U. Schallreuter
Jeremy Moore
Desmond J. Tobin
Nicholas J.P. Gibbons
Harriet S. Marshall
Tracey Jenner
Wayne D. Beazley
John M. Wood
Melanocortins and the Treatment of Nervous System Disease: Potential Relevance to the Skin
342(8)
Willem Hendrik Gispen
Roger A.H. Adan
The Skin POMC System (SPS): Leads and Lessons from the Hair Follicle
350(14)
Ralf Paus
Vladimir A. Botchkarev
Natalia V. Botchkareva
Lars Mecklenburg
Thomas Luger
Andrzej Slominski
Part VII. Poster Papers
Expression of MCI-and MC5-Receptors on the Human Mast Cell Line HMC-1
364(4)
M. Artuc
A. Grutzkau
Th. Luger
B.M. Henz
Characterization of μ-Opiate Receptor in Human Epidermis and Keratinocytes
368(4)
M. Bigliardi-Qi
P.L. Bigliardi
S. Buchner
T. Rufli
Characterization of a Polyclonal Antibody Raised Against the Human Melanocortin-1 Receptor
372(11)
Markus Bohm
Thomas Brzoska
Ursula Schulte
Meinhard Schiller
Ulrich Kubitscheck
Thomas A. Luger
Effects of Ethanol Consumption on β-Endorphin Levels and Natural Killer Cell Activity in Rats
383(4)
Nadka Boyadjieva
Gary Meadows
Dipak Sarkar
Murine Dendritic Cells Express Functional Delta-Type Opioid Receptors
387(4)
Clemens Esche
Valeria P. Makarenkova
Natalia V. Kost
Michael T. Lotze
Andrey A. Zozulya
Michael R. Shurin
Expression of Corticotropin Releasing Hormone in Malignant Melanoma
391(3)
Yoko Funasaka
Hirofumi Sato
Masamitsu Ichihashi
Depression Modulates Pruritus Perception: A Study of Pruritus in Psoriasis, Atopic Dermatitis and Chronic Idiopathic Urticaria
394(2)
Madhulika A. Gupta
Aditya K. Gupta
β-MSH Immunomodulation Acts via Rel/NF-κB in Cutaneous and Ocular Melanocytes and in Melanoma Cells
396(4)
J.W. Haycock
M. Wagner
R. Morandini
G. Ghanem
I.G. Rennie
S. MacNeil
Microinjection of Alpha-MSH Followed by UV-Irradiation Blocks HSP 72 in Human Keratinocytes
400(5)
Bjorn Held
Susanne Amato
Ernst G. Jung
Christiane Bayerl
β-Endorphin Binding and Regulation of Cytokine Expression in Langerhans Cells
405(9)
Junichi Hosoi
Hiroaki Ozawa
Richard D. Granstein
α-MSH Reduces Vasculitis in the Local Shwartzman Reaction
414(5)
Cord Sunderkotter
H. Kalden
T. Brzoska
Clemens Sorg
Thomas A. Luger
Implications of the Phenotype of POMC Deficiency for the Role of POMC-Derived Peptides in Skin Physiology
419(3)
Heiko Krude
Dirk Schnabel
Werner Luck
Annette Gruters
Serotonin in Human Allergic Contact Dermatitis
422(5)
L. Lundeberg
E. Sundstrom
K. Nordlind
A. Verhofstad
O. Johansson
Differential Temporal and Spatial Expression of POMC mRNA and of the Production of POMC Peptides During the Murine Hair Cycle
427(3)
J. E. Mazurkiewicz
D. Corliss
A. Slominski
Effective Treatment of Pruritus with Naltrexone, an Orally Active Opiate Antagonist
430(3)
D. Metze
S. Reimann
T.A. Luger
Developmentally Regulated Expression of α-MSH and MC-1 Receptor in C57BL/6 Mouse Skin Suggests Functions Beyond Pigmentation
433(7)
V.A. Botchkarev
N.V. Botchkareva
A. Slominski
B. Roloff
T. Luger
R. Paus
Plasma β-Endorphin Concentrations During Natural and Artificially Induced Winter Hair Growth in Mink (Mustela vison)
440(4)
J. Rose
K. Wood
J. Billingsley
J. Olbertz
A. Lovering
J. Carr
Expression of Proopiomelanocortin Peptides and Prohormone Convertases by Human Dermal Microvascular Endothelial Cells
444(4)
Thomas E. Scholzen
Thomas Brzoska
Dirk-Henner Kalden
Mechthild Hartmeyer
Thomas A. Luger
Cheryl A. Armstrong
John C. Ansel
ACTH Production in C57BL/6 Mouse Skin
448(3)
Andrzej Slominski
Natalia V. Botchkareva
Vladimir A. Botchkarev
Ashok Chakraborty
Thomas Luger
Murat Uenalan
Ralf Paus
Coexpression of Nitric Oxide Synthase and POMC Peptides in the Dystrophic C57BL/6J Mouse
451(4)
Margaret E. Smith
Ravinder K. Phul
Ligand Binding Profile and Effects of Melanin-Concentrating Hormone on Fish and Mammalian Skin Cells
455(4)
T. Suply
B. Cardinaud
S. Kanamori
C. Dal Farra
S. Ricois
J.L. Nahon
Occurrence of Four MSHs in Dogfish POMC and Their Immunomodulating Effects
459(5)
Akiyoshi Takahashi
Yutaka Amemiya
Masahiro Sakai
Akikazu Yasuda
Nobuo Suzuki
Yuichi Sasayama
Hiroshi Kawauchi
Specific Binding Sites for β-Endorphin on Keratinocytes
464(2)
K. Egeling
H. Muller
B. Karschunke
M. Tschischka
V. Spennemann
B. Hain
H. Teschemacher
Skin POMC Peptides: Their Binding Affinities and Activation of the Human MCI Receptor
466(4)
Marina Tsatmalia
Kazumasa Wakamatsu
Alison J. Graham
Anthony J. Thody
The Expression of α-MSH by Melanocytes Is Reduced in Vitiligo
470(4)
Alison Graham
Wiete Westerhof
Anthony J. Thody
α-MSH Inhibits Lipopolysaccharide Induced Nitric Oxide Production in B16 Mouse Melanoma Cells
474(3)
Marina Tsatmali
Philip Manning
Calum J. McNeil
Anthony J. Thody
Index of Contributors 477

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