Drugs of Natural Origin: Economic and Policy Aspects of Discovery, Development, and Marketing

by Artuso; Anthony

• ISBN13: 9780789001238
• ISBN10: 0789001233
• eBook ISBN(s): 9781135409012
• Edition: 1st
• Format: Hardcover
• Copyright: 1997-10-08
• Publisher: Routledge

Summary

Univ. of Charleston, SC. Presents a detailed model of the value of natural biological resources of pharmaceutical research and development. For pharmaceutical researchers. Hardcover (softcover available).

Table of Contents

Chapter 1. Biodiversity and the Search for New Drugs	1	(20)
Introduction	1	(2)
Prospecting Locations and Species Extinction	3	(1)
Estimating the Value of Biodiversity for Pharmaceutical R&D	4	(5)
The Natural Product Research Process in the Pharmaceutical Industry	9	(3)
Prospecting Strategies	12	(4)
Selecting a Prospecting Strategy	16	(1)
Biochemical Prospecting and Other Methods of Drug Discovery	17	(4)
Chapter 2. A Model of the Biochemical Prospecting Process	21	(44)
Introduction	21	(1)
The Basic Model	22	(6)
Defining the R&D Process	28	(1)
Some Complications to the Basic Model	29	(2)
Applying the Model	31	(31)
Potential Applications and Extensions of the Model	62	(3)
Chapter 3. Host Country Options for Conservation and Sustainable Development	65	(48)
Introduction	65	(1)
Evaluating a Proposed Biochemical Prospecting Opportunity	66	(30)
Strategies for Sustainable Development of Biological Resources	96	(17)
Chapter 4. Contractual Arrangements for Allocating Risks and Rewards	113	(26)
Introduction	113	(1)
Exclusive Prospecting Rights	113	(4)
Allocating Financial Risks and Returns	117	(2)
Variation in Returns from Royalty and Profit-Sharing Agreements	119	(4)
Profit Sharing	123	(6)
Other Arrangements for Allocating Financial Risks and Returns	129	(3)
Supply Guarantees and Renegotiation Clauses	132	(1)
A Market for Royalty Rights and Profit Shares	133	(2)
Technology Transfer, Training, and Technical Assistance	135	(2)
Intellectual Property Rights	137	(1)
Summary and Conclusions	137	(2)
Chapter 5. International Policy Implications	139	(24)
Political Economy of Biological Resources	139	(3)
The Biodiversity Convention	142	(2)
Potential Impediments to an Efficient Biochemical Prospecting Market	144	(6)
International Policy Options	150	(10)
Summary and Conclusions	160	(3)
Appendix A. Simulated Distribution of Returns from Biochemical Prospecting Opportunity	163	(6)
Appendix B. Two-Period, Two-Site, Dynamic Programming Land-Use Planning	169	(8)
Notes	177	(6)
References	183	(10)
Index	193