Epilepsy and Mental Retardation

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  • Format: Hardcover
  • Copyright: 1999-08-01
  • Publisher: Routledge

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The latest in our successful series of epilepsy edited by this experienced Scandinavian group addressed the clinically challenging area of epilepsy in mentally retarded patients. While epilepsy and intellectual disability are frequently comorbid (each may precipitate the other and both can be a consequence of brain damage), their elucidation can be complex; there is a high risk of misdiagnosis due to the occurence in mentally retarded patients of paroxysmal phenomena which resemble epileptic seizures, and the presentation of other psychiatric problems can obscure symptoms of epilepsy. Treatment too, is problematic with a tendency towards polytherapy with its increased risk of undesirable side effects which are less easily discovered and poorly tolerated in mentally retarded patients.Such patients have in the past usually been institutionalized but they are now more often in ambulatory or primary care, There is thus a greater than ever need to recognize the particular difficulties involved withtheir care.This book clarifies interrelationships between mental retardation, intellectual deterioration, and epilepsy and delivers practical solutions to the problems associated with accurate diagnosis, treatment, and long term management of epilepsy in patients with intellectual disabilities.

Author Biography

Marja Aikia, Department of Neurology, University of Kuopio Albert P. Aldenkamp, Department of Behavioural Sciences, Epilepsy Centre Kempenhaeghe Helge Bjornaes, The National Center for Epilepsy Eylert Brodtkorb, Department of Neurology, Trondheim University Hospital Stephen W. Brown, Learning Disabilities Service, Norwich Community Health Partnership, Little Plumstead hospital Hannu Heiskala, Rinnekoti Foundation Olaf Henriksen, The National Center for Epilepsy Matti Iivanainen, Hospital for Children and Adolescents, Department of Neurology, University of Helsinki Orla Janum, Dianalund Epilepsy Hospital Reetta Kalviainen, Department of Neurology, University of Kuopio Markus Kaski, Rinnekoti Foundation Karl O. Nakken, The National Center for Epilepsy Per Olesen, Dianalund Epilepsy Hospital Ingrid Olsson, Department of Paediatrics, Sahlgrenska University Hospital Kaarina Partanen, Department of Radiology, University of Kuopio Asla Pitkanen, A.I. Virtanen Institute, University of Kuopio Geir K. Roste, The National Hospital Anne Sabers, Dianalund Epilepsy Hospital Tuuli Salmenpera, Departments of Neurology and Neurosciences, University of Kuopio Matti Sillanpaa, Department of Child Neurology, Turku University Hospital TYKS Liselotte Sorensen, Dianalund Epilepsy Hospital Troels Sorensen, Department of Stroke, Hvidovre Hospital Carl E. Stafstrom, Division of Paediatric Neurology, New England Medical Center Suzanne Steffenburg, Department of Paediatrics and Child and Adolescent Psychiatry Ulf Steffenburg, Department of Paediatrics and Child and Adolescent Psychiatry, Sahlgrenska University Karin van Bronswijk, Department of Behavioural Sciences, Epilepsy Centre Kempenhaeghe

Table of Contents

Contributors vii(2)
Preface ix(2)
Foreword xi
1 Definitions and Epidemiology
Matti Sillanpaa
2 Mechanisms of Epilepsy in Mental Retardation: Insights from Angelman Syndrome, Down Syndrome and Fragile X Syndrome
Carl E. Stafstrom
3 Epilepsy in Down Syndrome
Anne Sabers
4 Epilepsy and Other Neuropsychiatric Morbidity in Mentally Retarded Children
Ulf Steffenburg
Suzanne Steffenburg
5 Diagnosing Epilepsy in Patients with Mental Retardation
Matti Iivanainen
6 Treatment of Epilepsy in Patients with Intellectual Disabilities: General Principles and Particular Problems
Eylert Brodtkorb
7 New Antiepileptic Drugs
Troels Sorensen
8 Epilepsy in Mental Retardation: The Role of Surgery
Olaf Henriksen
Helge Bjornaes
Geir K. Roste
9 Epilepsy Dementia: Intellectual Deterioration as a Consequence of Epileptic Seizures
Stephen W. Brown
10 Cognitive Side-Effects as an Outcome Measure in Antiepileptic Drug Treatment: The Current Debate
Albert P. Aldenkamp
Karin van Bronswijk
11 Seizure-Induced Damage to the Medial Temporal Lobe in Temporal Lobe Epilepsy
Asla Pitkanen
Tuuli Salmenpera
Marja Aikia
Kaarina Partanen
Reetta Kalviainen
12 Prevention of Seizure-Induced Neuronal Damage and Intellectual Deterioration: Experimental Aspects and Clinical Implications
Reetta Kalviainen
Asla Pitkanen
13 Epilepsy Services for the Patient with Mental Retardation in Denmark
Per Olesen
Liselotte Sorensen
Orla Janum
14 Epilepsy Services for the Patient with Mental Retardation in Finland
Hannu Heiskala
Markus Kaski
15 Epilepsy Services for the Patient with Mental Retardation in Norway
Karl O. Nakken
Eylert Brodtkorb
16 Epilepsy Services for the Patient with Mental Retardation in Sweden
Ingrid Olsson
Index 205

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