Essential Developmental Biology

by Slack, Jonathan M. W.; Dale, Leslie

• ISBN13: 9781119512851
• ISBN10: 1119512859
• Edition: 4th
• Format: Paperback
• Copyright: 2021-12-01
• Publisher: Wiley-Blackwell

Summary

ESSENTIAL DEVELOPMENTAL BIOLOGY

Discover the foundations of developmental biology with this up to date and focused resource from two leading experts

The newly revised Fourth Edition of Essential Developmental Biology delivers the fundamentals of the developmental biology of animals. Designed as a core text for undergraduate students in their first to fourth years, as well as graduate students in their first year, the book is suited to both biologically based and medically oriented courses. The distinguished authors presume no prior knowledge of development, animal structure, or histology.

The new edition incorporates modern single cell transcriptome sequencing and CRISPR/Cas9, as well as other methods for targeted genetic manipulation. The existing material has also been reorganized to provide for easier reading and learning for students. The book avoids discussions of history and experimental priority and emphasizes instead the modern advances in developmental biology. The authors have kept the text short and focused on the areas truly central to developmental biology. Readers will benefit from the inclusion of such topics as:

A thorough discussion of the groundwork of developmental biology, including developmental genetics, cell signaling and commitment, and cell and molecular biology techniques

An exploration of major model organisms, including Xenopus, the zebrafish, the chick, the mouse, the human, Drosophila, and Caenorhabditis elegans

A treatment of organogenesis, including postnatal development, and the development of the nervous system, mesodermal organs, endodermal organs, and imaginal discs in drosophila

A final section on growth, stem cell biology, evolution, and regeneration

Perfect for undergraduate students, especially those preparing to enter teaching or graduate studies in developmental biology, Essential Developmental Biology will also earn a place in the libraries of those in the pharmaceutical industry expected to be able to evaluate assays based on developmental systems.

Author Biography

Professor Jonathan M.W. Slack is an emeritus professor of the University of Bath, UK, where he was Head of the Department of Biology and Biochemistry; and the University of Minnesota, USA, where he was director of the Stem Cell Institute. He is a member of the European Molecular Biology Organization and a ??Fellow of the Academy of Medical Sciences. He has published numerous research papers on developmental biology as well as five other books, including The Science of Stem Cells (Wiley-Blackwell 2018).

Professor Leslie Dale is Professor of Developmental Biology at University College London, UK, where he was Head of Teaching for the Department of Cell and Developmental Biology. He teaches developmental biology to both undergarduate and medical students. For his PhD he studied regeneration in Drosophila imaginal discs and subsequently the development of Xenopus embryos.

Table of Contents

Preface

Section 1: Groundwork

1 The excitement of developmental biology

2 How development works

3 Approaches to development: developmental genetics

4 Approaches to development: cell signaling and commitment

5 Approaches to development: cell and molecular biology techniques

6 Cells into tissues

Section 2: Major model organisms

7 Model organisms

8 Xenopus

9 The zebrafish

10 The chick

11 The mouse

12 The human

13 Drosophila

14 Caenorhabditis elegans,

Section 3: Organogenesis

15 Techniques for studying organogenesis and postnatal development

16 Development of the nervous system

17 Development of mesodermal organs

18 Development of endodermal organs

19 Drosophila imaginal discs

Section 4: Growth, evolution, regeneration

20 Tissue organization and stem cells

21 Growth, aging, and cancer

22 Pluripotent stem cells and their applications

23 Evolution and development

24 Regeneration of missing parts

Glossary

Index