Fetal and Neonatal Brain Injury

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  • Edition: 4th
  • Format: Hardcover
  • Copyright: 2009-07-27
  • Publisher: Cambridge University Press
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Supplemental Materials

What is included with this book?


Improvements in the detection of fetal and neonatal brain injuries, advances in our understanding of the pathophysiology, cellular and molecular bases of encephalopathy, and new treatment options have all combined to produce significant changes in the management of neonatal brain disorders in the past few years. This new edition of Fetal and Neonatal Brain Injury brings the reader fully up to date with all advances in clinical management and outcome assessment. New material includes pregnancy-induced hypertension, HELLP syndrome and chronic hypertension, complications of multiple gestation, neurogenic disorders of the brain, neonatal stroke and much more. An expanded, highly illustrated chapter on structural and functional imaging of the fetal and neonatal brain is also included. An outstanding international team of highly experienced neonatologists and maternal-fetal medicine clinicians have produced a practical, authoritative clinical text that gives clear management advice to all clinicians involved in the treatment of these patients.

Table of Contents

Neonatal encephalopathy
Mechanisms of neurodegeneration and therapeutics in animal modes of neonatal hypoxic-ischemic encephalophathy
Cellular and molecular biology of hypoxic-encephalopathy
The pathogenesis of preterm brain injury
Prematurity and complications of labor and delivery
Risks and complications of multiple gestations
Intrauterine growth restriction
Maternal diseases that affect fetal development
Obstetrical conditions and practices that affect the fetus and newborn
Fetal and neonatal injury as a consequence of maternal substance abuse
Pregnancy induced hypertension, HELLP syndrome and chronic hypertension
Complications of labor and delivery
Fetal response to asphyxia
Antepartum evaluation of fetal well-being
Intrapartum evaluation of the fetus
Clinical manifestations of hypoxic-ischemic encephalopathy
The use of EEG in assessing acute and chronic brain damage in the newborn
Neuroimaging in the evaluation of pattern and timing of fetal and neonatal brain abnormalities
Light-based functional assessment of the brain
Placental pathology and the etiology of fetal and neonatal brain injury
Correlations of clinical, laboratory, imaging and placental findings as to the timing of asphyxial events
Congenital malformations of the brain
Neurogenetic disorders of the brain
Hemorrhagic lesions of the CNS
Neonatal stroke
Hypoglycemia in the neonate
Hyperbilirubinemia and kernicterus
Polycythemia and fetal-maternal bleeding
Hydrops fetalis
Bacterial sepsis in the neonate
Neonatal bacterial meningitis
Neurological sequelae of congenital perinatal infection
Perinatal human immunodeficiency virus infection
Inborn errors of metabolism with features of HIE
Acidosis and alkalosis
Meconium staining and the meconium aspiration syndrome
Persistent pulmonary hypertension of the newborn
Pediatric cardiac surgery: relevance to fetal and neonatal brain injury
Neonatal resuscitation: immediate management
Improving performance, reducing error, and minimizing risk in the delivery room
Extended management following resuscitation
Endogenous and exogenous neuroprotective mechanisms after hypoxic ischemic injury
Neonatal seizures
Nutritional support of the asphyxiated infant
Early childhood neurodevelopmental outcome of preterm infants
Assessment and management of infants with cerebral palsy
Long term impact of neonatal events on speech, language development and academic achievement
Neurocognitive outcomes of term infants with perinatal asphyxia
Appropriateness of intensive care application
Medicolegal issues in perinatal brain injury
Table of Contents provided by Publisher. All Rights Reserved.

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