9780192626400

Fetal and Neonatal Brain Injury Mechanisms, Management, and the Risks of Practice

by ;
  • ISBN13:

    9780192626400

  • ISBN10:

    019262640X

  • Edition: 2nd
  • Format: Hardcover
  • Copyright: 1997-04-24
  • Publisher: Oxford University Press
  • View Upgraded Edition
  • Purchase Benefits
List Price: $211.73

Summary

This book evaluates the numerous events in pregnancy, labor, and post-partum care that can lead to brain damage in newborn infants. The mechanisms by which the brain is damaged, as well as the approaches to treatment and most importantly, prevention of injury are detailed. Sixteen new chapters have been added to the Second Edition, and all the others have been fully updated. New chapters cover subjects such as ischemic cell injury, reperfusion injury, experimental models of perinatal brain injury, hypoxemic-ischemic encephalopathy, congenital malformations of the brain, perinatal infections, and metabolic disorders in the developing CNS. A chapter devoted exclusively to hemorrhagic lesions of the brain has been added as well. The new edition incorporates the most recent advances in neurology, neurosurgery, and neuroimaging, including the rapidly improving imaging techniques for identifying the extent of brain injury, the better ante- and post-partum management of infants, and the development of better understanding of the cellular mechanism of injuries to the brain.

Table of Contents

List of contributors xix
I POSSIBLE CAUSES OF ACQUIRED FETAL AND NEONATAL BRAIN INJURY 3(164)
1 Epidemiology of perinatal asphyxia
3(21)
Philip Sunshine
2 Mechanisms of ischemic cell injury
24(14)
Rona G. Giffard
Marios C. Papadopoulos
3 Ischemia-reperfusion injury
38(22)
Charles Palmer
4 Experimental models of perinatal brain injury
60(11)
Alistair J. Gunn
Harmen H. de Haan
Peter D. Gluckman
5 Fetal responses to asphyxia
71(21)
R. Harold Holbrook Jr
Ronald N. Gibson
Yasser Y. El-Sayed
Daniel S. Seidman
6 Prematurity and complications of labor and delivery
92(16)
Maurice L. Druzin
7 Endogenous neuroprotective mechanisms -- their implications for therapeutic intervention
108(7)
Chris E. Williams
Maggie Lai
Peter D. Gluckman
8 Intrauterine growth retardation
115(21)
Alistair G.S. Philip
Philip Sunshine
9 Congenital malformations of the brain
136(15)
Ronald J. Lemire
10 Hemorrhagic lesions of the central nervous system
151(16)
Seetha Shankaran
II ENVIRONMENTAL CAUSES OF ACQUIRED FETAL AND NEONATAL BRAIN INJURY 167(110)
11 The use of intrapartum fetal heart rate monitoring to reduce perinatal asphyxia in the term infant
167(14)
Dermot MacDonald
12 Tocolytic therapy for preterm labor
181(9)
Paul B. Meyer
Yasser El-Sayed
Maurice L. Druzin
13 Fetal and neonatal injury as a consequence of maternal substance abuse
190(26)
Louis P. Halamek
14 Neurologic sequelae of congenital infections
216(16)
Charles G. Prober
Ann M. Arvin
15 Neonatal bacterial meningitis
232(16)
Alistair G.S. Philip
16 Perinatal HIV infection
248(17)
Yvonne A. Maldonado
17 Metabolic disorders of the mother affecting the fetus
265(12)
Anne C. Regenstein, M.D.
III DIAGNOSING THE INFANT WITH ASPHYXIA 277(126)
18 Hypoxemic-Ischemic encephalopathy
277(10)
Jin S. Hahn
Edward J. Novotny Jr
19 Use of the electroencephalogram in assessing acute brain damage in the newborn
287(15)
Barry R. Tharp
20 Imaging of neonatal hypoxic-ischemic cerebral damage
302(54)
Dieter R. Enzmann
21 Correlation of clinical findings and timing of the asphyxial event
356(18)
Jin S. Hahn
22 Neonatal asphyxic brain injury is neural system preferential and targets sensory-motor networks
374(29)
Lee J. Martin
Ansgar Brambrink
Raymond C. Koehler
Richard J. Traystman
IV MANAGEMENT OF THE DEPRESSED OR NEUROLOGICALLY DYSFUNCTIONAL INFANT 403(80)
23 Immediate management
403(12)
William E. Benitz
Lorry R. Frankel
David K. Stevenson
24 Extended management
415(17)
William E. Benitz
Lorry R. Frankel
David K. Stevenson
Philip Sunshine
25 The management of neonatal seizures
432(30)
Robert R. Clancy
26 Nutritional support of the asphyxiated infant
462(21)
John A. Kerner Jr
Anjali Malkani
William J. Wenner Jr
V SPECIFIC ABNORMALITIES ASSOCIATED WITH FETAL AND NEONATAL BRAIN INJURY 483(102)
27 Hypoglycemia in the neonate
483(16)
Marvin Cornblath
Robert Schwartz
28 Hematologic disorders: anemia, polycythemia, and hyperbilirubinemia
499(13)
David K. Stevenson
Herbert C. Schwartz
Phyllis A. Dennery
29 Acidosis/alkalosis
512(15)
Robert Vannucci
30 Hydrops fetalis
527(5)
Roderic H. Phibbs
31 Polycythemia
532(7)
Ted S. Rosenkrantz
William Oh
32 Meconium staining and the meconium aspiration syndrome
539(25)
Thomas E. Wiswell
33 Persistent pulmonary hypertension of the newborn
564(21)
William E. Benitz
William D. Rhine
Krisa P. Van Meurs
VI ASSESSING THE CAUSES OF PERMANENT NEUROLOGIC DISABILITY 585(58)
34 The relationship of placental pathology to causation of detrimental pregnancy outcome
585(17)
Geoffrey Altshuler
35 The scope and limitations of neurologic and behavioural assessments of the newborn
602(13)
Anneliese F. Korner
36 Long-term follow-up of term infants with perinatal asphyxia
615(16)
Charlene M.T. Robertson
37 Appropriateness of intensive care application
631(12)
Ernle W.D. Young
Index 643

Rewards Program

Reviews for Fetal and Neonatal Brain Injury Mechanisms, Management, and the Risks of Practice (9780192626400)