Foundations of Clinical Research Applications to Practice

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  • Edition: 3rd
  • Format: Hardcover
  • Copyright: 2007-12-31
  • Publisher: Prentice Hall
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Supplemental Materials

What is included with this book?


Provides the foundations that are necessary for finding and interpreting research evidence across all healthcare professions.Revised to reflect the most current changes in the field of clinical research in rehabilitation and medicine, including the growing emphasis on evidence-based practice (EBP) that has become central to all of health care and the new vocabulary that is being integrated into research and practice across disciplines. There is also a new chapter on systematic reviews and meta-analysis as well as expanded content related to clinical decision making, including likelihood ratios, pretest and posttest probabilities, minimally important change and number needed to treat. For those in the health professions, including physical therapy, occupational therapy, speech therapy, nursing, and exercise physiology.

Author Biography

Dr. Leslie Portney is the Director of Graduate Programs in Physical Therapy for the MGH Institute of Health Professions. Leslie graduated with a Doctor of Physical Therapy from the MGH Institute, a PhD in Gerontology from Boston University, a Master of Science in Physical Therapy from Medical College of Virginia, and a Certificate in Physical Therapy from the University of Pennsylvania. She is a licensed physical therapist in both New York and Massachusetts.  Leslie has authored a multitude of books and has contributed to a variety of different publications including the PT—Magazine of Physical Therapy.  Leslie is currently a member of the American Physical Therapy Association and on the Task Force on Uniform Outcomes Assessment.


Dr. Mary Watkins is a Clinical Associate Professor in the Graduate Programs in Physical Therapy for the MGH Institute of Health Professions.  Mary graduated with a Doctor of Physical Therapy from the MGH Institute and a Master of Science from Boston University.  Mary is a licensed physical therapist in Massachusetts, a member of the American Physical Therapy Association. Mary has authored many book chapters and contributed to a number of different publications including the Journal of Hand Therapy, the Journal of Bone and Joint Surgery, Journal of the American Medical Association, Journal of Occupational Rehabilitation and the Journal of Orthopedic & Sports Physical Therapy. 

Table of Contents

Foundations of Clinical Research
A Concept of Clinical Research
The Role of Theory in Clinical Research
Ethical Issues in Clinical Research
Concepts of Measurement
Principles of Measurement
Reliability of Measurements
Validity of Measurements
Designing Clinical Research
Asking the Research Question
Validity in Experimental Design
Experimental Designs
Quasi-Experimental Designs
Single Subject Designs
Exploratory Research: Observational Designs
Descriptive Research
Surveys and Questionnaires
Systematic Reviews and Meta-Analyses
Data Analysis
Descriptive Analysis
Statistical Inference
Comparing Two Means: The t-test
Comparing More Than Two Means: Analysis of Variance
Multiple Comparison Tests
Nonparametric Tests for Group Comparisons
Measures of Association for Categorical Variables: Chi-Square
Statistical Measures of Reliability
Statistical Measures of Validity
Epidemiology: Measures of Risk
Multivariate Analysis
Data Management
Writing a Research Proposal
Reporting the Results of Clinical Research
Evaluating Research Reports
Table of Contents provided by Publisher. All Rights Reserved.

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