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9780471899815

Handbook of Animal Lectins Properties and Biomedical Applications

by
  • ISBN13:

    9780471899815

  • ISBN10:

    047189981X

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2000-11-08
  • Publisher: WILEY
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Supplemental Materials

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Summary

This comprehensive yet concise guide to animal lectins, covers all sources from unicellular protozoa and slime moulds through invertebrates to mammals and birds, and provides essential information to the widest possible readership. The last few years have seen an explosion of interest and research in animal lectins, and this book, which is divided into two parts, provides a compendium of galectins, collectins, selectins, pentraxins and other carbohydrate-binding proteins from throughout the animal kingdom. The first part introduces animal lectins on both phylogenetic and structural bases and outlines their key biomedical applications. The second, and major part, is a quick reference alphabetical directory listing around 170 lectins. Each lectin entry provides, where known, details of its: Isolation Structure Biological activities Tissue and/or subcellular distribution Possible functions Applications A bibliography for each lectin is also included and useful appendices list lectins according to their sugar specificity, characterised lectins of human origin by tissue source and commercial suppliers of animal lectins. This superb book is aimed at basic scientists and clinicians alike, and will be invaluable to both established research workers and newcomers to this area. It will be of particular interest to biochemists, cell biologists, immunologists, oncologists, pharmacologists, medical practitioners and students of medical and biological sciences.

Author Biography

David C. Kilpatrick is the author of Handbook of Animal Lectins: Properties and Biomedical Applications, published by Wiley.

Table of Contents

Preface vii
Abbreviations ix
Safety Notice xi
Introduction to Animal Lectins
1(10)
Definition of a lectin
1(2)
Historical overview of animal lectins
3(2)
Comparison of plant and animal lectins
5(2)
Outline of this book
7(4)
Invertebrate Lectins
11(20)
Lectins from slime moulds, protozoa and sponges
11(4)
Mollusc lectins
15(1)
Annelid lectins
16(1)
Arthropod lectins
17(4)
Echinoderm lectins
21(1)
Protochordate (tunicate) lectins
22(9)
Vertebrate Lectins
31(28)
S-type (galectins)
31(4)
C-type (general)
35(1)
C-type (hyalectans)
36(1)
C-type (collectins)
36(6)
C-type (selectins)
42(2)
C-type (membrane receptors)
44(2)
Pentraxins
46(1)
I-type lectins
47(1)
P-type lectins
48(1)
Ficolins
48(1)
Cytokine lectins
49(10)
Biomedical Applications of Animal Lectins
59(20)
Blood grouping reagents
59(1)
Mitogenic agents
60(2)
Lectins and haemostasis
62(1)
Lectins and reproduction
63(1)
Lectins and immunity
64(2)
Lectins and cancer
66(3)
Endogenous lectins as drugs and drug targets
69(10)
Alphabetical Directory of Animal Lectins
79(378)
Appendix A: Classification of lectins according to sugar specificity 457(5)
Appendix B: Lectins of human origin by tissue source 462(2)
Appendix C: Commercial suppliers of animal lectins 464(2)
Index 466

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