Handbook of Dermatology A Practical Manual

by Mann, Margaret W.; Berk, David R.; Popkin, Daniel L.; Bayliss, Susan J.

• ISBN13: 9781444308112
• ISBN10: 1444308114
• Edition: 1st
• Format: eBook
• Copyright: 2009-03-12
• Publisher: Wiley-Blackwell

Summary

Because dermatology is a complex visual specialty that mixes medical and surgical approaches to management, trainees need fast access to a wide range of material. This concise new reference uses tables, algorithms, protocols, guidelines, and staging and scoring systems to present succinct guidance on best-practice patient care. Structured around three components -- medical, surgical, and pharmacological -- the book consolidates the core Board exam information residents most often look up. Handbook of Dermatology: A Practical Manual  was road-tested as it was developed to ensure usefulness for dermatology residents, dermatologists, and family physicians.

Author Biography

Margaret W. Mann, Division of Dermatology, Washington University, St Louis, Missouri, USA

David R. Berk, Division of Dermatology, Washington University, St Louis, Missouri, USA

Daniel L. Popkin, Division of Dermatology, Washington University, St Louis, Missouri, USA

Susan J. Bayliss, Division of Dermatology, Washington University, St Louis, Missouri, USA

Table of Contents

Preface, xi

Dedication, xii

Abbreviations, xiii

Part 1 General Dermatology

Work-up Quick Reference, 3

Direct immunofl uorescence – where to biopsy?, 3

False positive/negative DIFs, 4

Biopsy for GVHD, 4

The Dermatologic Differential Algorithm, 4

Alopecia Work-Up, 5

Associations, 5

Cicatricial or non-cicatricial?, 5

Aphthosis Classifi cation and Workup, 9

Morphologic classifi cation, 9

Classifi cation by cause, 9

Work-up for complex apthae, 9

Treatment, 9

Amyloidoses, 10

Xanthomas, 11

Hyperlipoproteinemias: Fredrickson Classifi cation, 12

Histiocytosis, 13

Lupus Erythematosus, 17

Systemic lupus erythematosus criteria (4 of 11), 17

Acute cutaneous lupus erythematosus, 17

Subacute cutaneous lupus erythematosus, 17

Chronic cutaneous lupus erythematosus, 17

Autoantibody sensitivities and specifi cities, 18

Antinuclear Antibodies, 20

Autoantibodies in Connective Tissue Diseases, 21

Vasculitis, 22

Treatment of ANCA-associated vasculitis, 22

Anti-neutrophil cytoplasmic antibody, 23

Small vessel vasculitis, 24

Medium (+/- small) vessel vasculitis, 26

Large vessel vasculitis, 27

Cryoglobulinemia, 28

CTCL Classifi cation, 29

Mycosis fungoides variants, 29

MF (TNMB) staging, 31

MF treatment algorithm, 32

Cutaneous B-cell Lymphoma, 33

Leukemia cutis, 33

Monoclonal Gammopathies, 34

Melanoma – Classifi cation, 35

Breslow depth, 36

Melanoma – staging and survival, 36

Melanoma – treatment guidelines, 37

Infectious Disease, 39

Viruses and diseases, 39

Human papillomavirus, 41

Other viral diseases, 42

Mycoses, 45

Vector-borne diseases, 52

Creatures in dermatology, 58

Immunology, 63

Complement, 63

Complement defi ciencies, 64

Angioedema and complement levels, 64

Th profiles, 65

Bullous Disorders, 65

Intracorneal/subcorneal, 65

Intraepidermal blisters, 66

Suprabasilar blisters, 66

Subepidermal with little infl ammation, 66

Subepidermal with lymphocytes, 67

Subepidermal with eosinophils, 67

Subepidermal with neutrophils, 67

Subepidermal with mast cells, 68

Epidermolysis bullosa, 68

Major bullous diseases – clinicopathologic fi ndings, 71

Glands, 75

Disorders or Drugs Associated with Skeletal, Ocular, and/or Nail Findings, 77

Dermatoses of Pregnancy, 88

Neonatal Vesiculopustular Eruptions, 90

Genital Ulcers, 95

Common Contact Allergens, 96

Features suggestive of specifi c irritant/toxin, 100

Plants and dermatoses, 100

Vitamin Defi ciencies/Hypervitaminoses, 103

Genodermatoses, 107

Gene list, 107

Chromosome abnormalities, 133

Tumors, 134

Disorders of cornifi cation, 136

Disorders of hair, nail, ectoderm, 139

Tumor syndromes, 144

Disorders of connective tissue, 146

Disorders of metabolism, 149

Disorders of pigmentation, 154

Disorders of vascularization, 156

Immunodefi ciency syndromes, 159

Miscellaneous, 162

Dermoscopy, 163

Pathology, 165

Histochemical staining, 165

Immunohistochemical staining, 167

Pathologic bodies, 170

Other derm path buzzwords, patterns, DDx, 175

Part 2 Surgery

Surgical Margins Guidelines, 183

Indications for Mohs micrographic surgery, 183

Guideline for Prophylactic Antibiotics, 184

Algorithm for antibiotic prophylaxis, 185

Guideline for Prophylactic Antivirals, 186

Anesthetics, 186

Dose calculation, 186

Tumescent anesthesia, 186

Topical anesthetic, 187

Adverse reaction to local anesthetics, 187

Local anesthetic, 188

Nerve blocks, 189

Surgical Anatomy, 189

Anatomy of the face, 189

Anatomy of the nail, 193

Danger zones in surgery, 194

Dermatomal distribution of sensory nerves, 196

Anatomy of the lower extremity venous system, 197

Cutaneous Reconstruction, 198

Undermining depths in reconstruction, 199

Dangerzone of the neck: Erbs point, 196

Second intention, 199

Simple linear closure, 200

Transposition fl ap, 201

Advancement fl ap, 204

Interpolation fl ap, 206

Rotation fl ap, 207

Skin graft, 208

Sutures, 210

Absorbable, 210

Non-absorbable, 211

Suture removal time, 212

Electrosurgery, 212

Wound Healing, 212

Wound dressing, 213

Antiseptic Scrubs, 214

Lasers, 216

Laser principles, 217

Thermal relaxation time, 217

Laser treatment of tattoo pigment, 218

Photoinduced eye injury, 218

Photodynamic Therapy, 220

Basic principles, 220

Applications, 220

Photosensitizer properties and options, 220

UV Spectrum, 222

UV Protection Measurements, 223

UV Associations/Specifi cities, 223

Glogau Wrinkle Scale, 224

Fitzpatrick Skin Type, 224

Peeling Agents, 224

TCA peel, 225

TCA peel frost level, 225

Jessner solution, 225

Baker-Gordon phenol, 226

Cook total body peel, 226

Pre-peel prep, 226

Post-peel wound care, 226

Botulinum Toxin, 226

Botox injection sites, 227

Fillers, 229

Sclerotherapy, 234

Determine vessel size using needle gauge, 236

Recommended maximum effective concentration of sclerosant to minimize side effects, 236

Part 3 Drugs and Therapies

Medication Quick Reference, 239

Topical steroids, 239

Non-steroidals, 240

Commonly used drugs in dermatology, 240

Systemic Medications, 243

Antimalarials, 243

Immunosuppressive agents, 244

Systemic retinoids, 246

Biologics, 247

General Reference, 249

Metric measurements, 249

Dosage calculation, 249

Drug dispensing and absorption, 249

Corticosteroid, 249

Acne – Topical, 250

Antibiotics, 250

Keratolytics, 250

Acne – Systemic, 251

Antibiotics, 251

Retinoids, 252

Others, 252

Alopecia, 252

Analgesics, 252

Anesthetics – Topical, 253

Antibiotics, 253

Topical/Antiseptic, 253

Systemic, 254

Antibiotic preoperative prophylaxis, see p. 184

Antibiotic regimens, 255

STDs, 257

Antifungals, 257

Topical, 257

Systemic, 258

Antifungal regimens, 260

Antiparasitics, 261

Antivirals, 262

For HSV labialis – topical agents, 262

For HSV 1 or 2 – oral agents, 262

For HSV disseminated disease, 262

For herpes zoster/VZV, 262

For genital warts, 263

For verruca vulgaris, 263

For molluscum, 263

Antihistamines, 263

Sedating, 263

Non-sedating, 264

H2-blockers, 264

Antipruritic, 264

Topical, 264

Oral, 264

Bleaching Agents/Depigmenting Agents, 265

Topical Chemotherapy, 266

Actinic keratoses (AK), 266

Basal cell carcinoma (BCC) – superfi cial BCC, 266

CTCL, 266

Topical agents, 266

Oral agent, 266

Other agent, 267

Psoriasis, 267

Topical agents, 267

Tar, 267

Systemic agents, 267

Seborrheic Dermatitis, 268

Hypertrichosis, 268

Hyperhidrosis, 268

Wound Care, 269

Vitamins/Nutritional Supplements, 269

Miscellaneous Meds, 269

Cytochrome P-450 Interactions, 270

Pregnancy Categories of Commonly Used Dermatologic Agents, 272

Common Dermatologic Drugs and Teratogenic Effects, 273

Dermatologic Drugs Reportedly Associated with Contraceptive Failure, 273

Drug Eruptions, 274

Chemotherapeutic Agents and Skin Changes, 277

Antidote to extravasation of chemotherapeutic agents, 279

UV Light Treatment, 279

UVA/UVB dosing, 279

NBUVB dosing, 280

PUVA, 280

Washington University Dermatology Toxic Epidermal Necrolysis (TEN) Protocol, 282

Diagnosis of TEN, 282

Triage algorithm for TEN patients, 283

Treatment for all TEN patients, 283

Index, 287

Color plate section can be found facing page 208