Handbook of Neurochemistry and Molecular Neurobiology: Neural Signaling Mechanisms

by Mikoshiba, Katsuhiko

• ISBN13: 9780387303383
• ISBN10: 0387303383
• Edition: 3rd
• Format: Hardcover
• Copyright: 2009-05-01
• Publisher: SPRINGER

Summary

This volume of the Handbook of Neurochemistry and Molecular Biology focuses on molecular events involved in synapse formation, synaptic plasticity and ongoing neural activity. The volume explores axonal growth cones, synapse development, and mechanisms of LTP and LTD, and calcium dynamics. Particular attention is given to function and trafficking of membrane proteins including various ion channels, aquaporines, gap junctions.

Table of Contents

Molecular events occuring during neural activity

Molecular events occuring during synaptic plasticity

Molecular mechanism of growth come formation

Molecular mechanism of LTP in hippocampus

Molecular mechanism of LTD in cerebellum

Development of synapse

Ion channels, neural function and disease

Aquaporine

NMDA receptor

C1-channel

Gap junction

AMPA receptor

nACH receptor

K channel

Muscarinic receptor

Glycine receptor

GABA receptor

Glutamate receptor

Ca channel

Catecholamine receptor

Indolamine

Phosphorylation

Protein kinase C

Bark

CaMK II

cdk5

P13 kinase

Postsynaptic signaling

Presynaptic signaling

Dynamism of ion channels and receptors: targeting, trafficking, degradation

Structural basis of ion channel gating and pore opening

Calcium signaling

Calineurin

IP3 receptor

Calreticulin

Ryandine receptor

Calcium channel

Ca pump

Signaling molecules

PLC

PLD

MgluR

Inositolpolyphosphates including PIP2

Lipid messengers

A skeletal protein as a signal interacting protein

Actin filament

Microtubes

Homer

S100 protein RAGE signaling in the central nervous system

Connexin mediated neuronal communication

Calcium regulation by EF-hand proteins in the brain

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