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9780123302205

Handbook of Toxicologic Pathology

by Haschek, Wanda M.; Rousseaux, Colin G.
  • ISBN13:

    9780123302205

  • ISBN10:

    012330220X

  • eBook ISBN(s):

    9781483288611

  • Additional ISBN(s):

    9780123302151

  • Format: Hardcover
  • Copyright: 1991-08-01
  • Publisher: Academic Pr
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Summary

This is the first comprehensive reference work on toxicologic pathology, an emerging field that integrates the mechanisms of toxic injury with the resulting pathology. Chapters deal systematically with organ-specific toxic injury, describing the mechanisms of injury, morphological expression of the injury, and evaluation of the pathology. Additional chapters introduce the field to the uninitiated and address such topics as techniques used for morphological evaluation, risk assessment, and regulatory aspects. The Handbook of Toxicologic Pathology will quickly establish itself as the classic reference work in this field for years to come.

Table of Contents

Toxicologic Pathology: An Introduction
The Pathologist in Toxicologic Testing and Evaluation
Evaluation of Altered Morphology
Quantitative Techniques for Morphological Evaluation
Biochemical Basis of Toxicity
Biochemical Mechanisms of Toxic Cell Injury
Chemical Carcinogenesis
Limitations of Toxicologic Pathology
Regulatory Aspects and Potential Pitfalls of Toxicologic Pathology
Risk Assessment
Skin and Oral Mucosa
Gastrointestinal Tract
Pancreas
Hepatobiliary System
Urinary System
Blood and Bone Marrow
Immune System
Skeletal System
Cardiovascular and Skeletal Muscular Systems
Nervous System
Endocrine System
Respiratory System
Male Reproductive System
Female Reproductive System
The Fetus
Radiation and Heat
Chapter References
Index
Table of Contents provided by Publisher. All Rights Reserved.

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