Harper's Illustrated Biochemistry, 28th Edition

by MURRAY

• ISBN13: 9780071625913
• ISBN10: 0071625917
• Additional ISBN(s): 9780071461979, 9780071765763
• Edition: 28th
• Format: Paperback
• Copyright: 2009-06-02
• Publisher: McGraw-Hill Medical
• More Book Details
• Purchase Benefits

Summary

Turn to the field's most trusted text for a complete understanding of the principles of biochemistry and molecular biology as they relate to modern medicine>/p>..Clear, concise, and now in full-color,Harper'sis unrivaled in its ability to clarify the link between biochemistry and the molecular basis of health and disease. ..The Twenty-Eighth Edition has undergone sweeping changes - including a conversion to full-color artwork and every chapter being substantially revised and updated - all to reflect the latest advances in knowledge and technology and to make the text as up-to-date and clinically relevant as possible. Combining outstanding full-color illustrations with integrated coverage of biochemical diseases and clinical information,Harper's Illustrated Biochemistryoffers an organization and clarity not found in any other text on the subject. ..Striking just the right balance between detail and brevity, Harpers Illustrated Biochemistry is essential for USMLE review and is the single best reference for learning the clinical relevance of a biochemistry topic. ...NEW to this edition: . Every chapter now begins with a Summary of the Biomedical Importance of its contents and concludes with a Summary reviewing the topics covered. Two all-new chapters: Free Radicals and Antioxidant Nutrients and Biochemical Case Histories which offers an extensive presentation of 16 pathophysical conditions . An Expanded Appendix containing a list of important biochemistry websites, data bases, and online journals .. NEW or updated coverage of important topics such as:.The influence of the Human Genome Project on the; biomedical fields;.Computer-aided drug delivery;.The attachment of influenza virus to human cells;.Next Generation Gene Sequencing platforms;.Methods of assaying enzymes;.Advanced glycation end-products and their importance in diabetes mellitus;.The major challenges facing medicine .....

Author Biography

David A. Bender, PhD,.Sub-Dean University College Medical School,.Senior Lecturer in Biochemistry,.Department of Structural and Molecular Biology and .Division of Medical Education, .University College London
..Kathleen M. Botham, PhD, DSc,.Professor of Biochemistry, Royal Veterinary.College, University of London
..Daryl K. Granner, MD,.Emeritus Professor of Molecular Physiology and Biophysics.and Medicine,.Vanderbilt University, Nashville, Tennessee
..Peter L. Gross MD, MSc, FRCP(C),.Associate Professor, Department of Medicine,.McMaster University
..Frederick W. Keeley, PhD,.Associate Director and Senior Scientist, Research Institute,.Hospital for Sick Children, Toronto, and Professor,.Department of Biochemistry, University of Toronto
..Peter J. Kennelly, PhD,.Professor and Head, Department of Biochemistry, .Virginia Polytechnic Institute and State University, .Blacksburg, Virginia
..Robert K. Murray, MD, PhD,.Professor (Emeritus) of Biochemistry,.University of Toronto
..Margaret L. Rand, PhD,.Associate Senior Scientist, Hospital for Sick Children, Toronto, .and Professor, Departments of Laboratory Medicine and Pathobiology .and Department of Biochemistry, University of Toronto
..Victor W. Rodwell, PhD,.Emeritus Professor of Biochemistry, Purdue University, West Lafayette,.Indiana
..P. Anthony Weil, PhD,.Professor of Molecular Physiology and Biophysics,.Vanderbilt University School of Medicine,.Nashville, Tennessee

..

Table of Contents

Biochemistry and Medicine

Water & PH

Amino Acids and Peptides

Proteins: Determination of Primary Structure

Proteins: Higher Orders of Structure

Proteins: Myoglobin and Hemoglobin

Enzymes: Mechanisms of Action

Enzymes: Kinetics

Enzymes: Regulation of Activities

Bioenergetics: The Role of ATP

Biologic Oxidation

The Respiratory Chain & Oxidative Phosphorylation

Carbohydrates of Physiologic Significance

lipids of Physiologic Significance

Overview of Metabolism

The Citric acid Cycle: The Catabolism of Acetyl-CoA

Glycolysis and Oxidation of Pyruvate

Metabolism of Glycogen

Gluconeogenesis and Control of the Blood Glucose

The Pentose Phosphate Pathway & other Pathways of Hexose Metabolism

Biosynthesis of Fatty Acids

Oxidation of Fatty Acids: Ketogenesis

Metabolism of Unsaturated Fatty Acids & Eicosanoids

Metabolism of Acyglycerols and Sphingolipids

Lipid Transport And Storage

Cholesterol Synthesis, Transport and Excretion

Integration of Metabolism- the Provision of Metabolic Fuels

Biosynthesis of Nutritionally Nonessential Amino Acids

Catabolism of Proteins & of Amino Acid Nitrogen

Catabolism of the Carbon Skeletons of Amino Acids

Conversion of Amino Acids

Porphyrins & Bile Pigments

Nucleotides

Metabolism of Purine & Pyrimidine Nucleotides

Nucleic Acid Structure and Function

DNA Organization, Replication and Repair

RNA Synthesis, Processing and Modifications

Protein Synthesis and Genetic Code

Regulation of Gene Expression

Molecular Genetics, Recombinant DNE and Genomic Technology

Membranes: Structure and Function

The Diversity of Endocrine System

Hormone Action and Signal Transduction

Nutrition, Digestion and Absorption

Vitamins and Minerals

Intracellular Traffic and Sorting of Proteins

Glycoprotein

The Extracellular Matrix

Muscle and the Cytoskeleton

Plasma Proteins and Immunoglobulins

Homeostasis and Thrombosis

The Red and White Blood Cells

Metabolism of Xenobiotics

The Human Genome Project

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