Hemostasis and Thrombosis Practical Guidelines in Clinical Management

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  • Edition: 1st
  • Format: Paperback
  • Copyright: 2014-05-12
  • Publisher: Wiley-Blackwell
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Supplemental Materials

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  • The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any access cards, study guides, lab manuals, CDs, etc.


Thrombotic and bleeding disorders affect at least 10 million people in the US alone. As a result there has been much more interest and research into this field. The field of haematology is undergoing major advances in thrombosis research, including significant additions to recommended treatment protocols and guidelines. This new handbook will cover all aspects of the practical mangement of commonly encountered thrombotic and bleeding disorders, with emphasis on clinical diagnosis, treatment and day-to-day management. It will distil the most clinically relevant material from the literature for all those working in the field of haemostasis and thrombosis.

Table of Contents

List of Contributors, xxx

Preface, xxx

1 Theories of Blood Coagulation:  Basic concepts and recent updates
Dougald M. Monroe, Maureane Hoffman

2 Vascular Endothelium, Influence on Hemostasis: Past and Present
Hussain I. Saba, Sabiha R. Saba

3 Coagulation testing: basic and advanced clinical laboratory tests for the diagnosis of common hemostatic and thrombotic disorders
Nils Egberg and Margareta Blombäck

4 Hemophilia A (Factor VIII Deficiency):  Clinical Bleeding and Management
Pier Mannuccio Mannucci and Massimo Franchini

5 Hemophilia B (Factor IX deficiency): clinical manifestations and management
R. S. Kasthuri, H. R. Roberts, P. E. Monahan

6 Factor XI Deficiency (Hemophilia C)
Charles E. Bane, Anne T. Neff, and David Gailani

7 Factor VIII and IX Inhibitors in Hemophilia 
Meera Chitlur and Jeanne Lusher

8 Treatment Options for Acquired Hemophilia
Anjali Sharathkumar and David Green

9 Factor XII Deficiency (Hageman Factor Deficiency)
Evi Stavrou and Alvin H. Schmaier

10 Inherited Combined Factor Deficiency States
Asma Latif and Louis Aledort

11 Acute and Chronic ITP: Biology, Diagnosis and Management
Samir Dalia and Benjamin Djulbegovic

12 Disseminated intravascular coagulation (DIC): diagnosis and management
Stephanie J Davis, Craig M Kessler

13 Mechanisms of fibrinolysis and basic principles of management
John W. Weisel and I. Litvinov

14 Post thrombotic Syndrome
Jean-Philippe Galanaud, Susan R. Kahn

15 Von Willebrand Disease:  Clinical Aspects and Practical Management
Francesco Rodeghiero, Alberto Tosetto, Giancarlo Castaman

16 Platelets in hemostasis: inherited and acquired qualitative disorders
Noman Ashraf  and Hussain I. Saba 

17 Contributions of Platelet Polyphosphate to Hemostasis and Thrombosis
James H. Morrissey

18 Thrombotic Microangiopathy:  Thrombotic Thrombocytopenic Purpura and Hemolytic Uremic Syndrome: Biology, Diagnosis and Management
Samir Dalia

19 Hemostasis and Aging
Lodovico Balducci

20 Hemostatic problems in chronic and acute liver disease
Ton Lisman and Robert J. Porte

21 Cancer and Thrombosis
Erica Peterson and Agnes Lee

22 An Update on Low-Molecular-Weight Heparins
Jawed Fareed, Debra Hoppensteadt, Walter P. Jeske


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