Hepatocellular Cancer: Diagnosis and Treatment

by Carr, Brian I.

• ISBN13: 9781603273732
• ISBN10: 1603273735
• eBook ISBN(s): 9781603273763
• Edition: 2nd
• Format: Hardcover
• Copyright: 2009-11-01
• Publisher: HUMANA PRESS
• More Book Details

Summary

Hepatocellular cancer is the the fifth most common cancer, with 600,000 new cases reported each year worldwide. Additionally, exciting changes in the science of HCC in the last four years have turned the practice of diagnosing and treating the disease upside down. In Hepatocellular Carcinoma: Diagnosis and Treatment, Second Edition, the leading experts in the field of HCC thoroughly update and expand upon the critically acclaimed first edition with all the latest developments in the diagnosis and treatment of primary liver cancer. The book details for physicians the diagnostic and therapeutic decision making process for dealing with such problems as incidental tumors in the liver transplant, the role of neo-adjuvant chemotherapy, intra-arterial vs intravenous therapy, the uses of embolization, and the significance of portal vein thrombus. New chapters discuss the introduction into clinical practice of cell cycle growth inhibitors, an expanded knowledge of Genomics and Proteomics, and novel ways of delivering intra-hepatic chemotherapy. This cutting-edge text is a vital resource and must have for today's hepatologists and medical and surgical oncologists.

Table of Contents

Epidemiology of Hepatocellular Carcinoma	p. 1
Environmental Carcinogens and Risk for Human Liver Cancer	p. 27
Primary Liver Cancer: Chemical Carcinogenesis	p. 55
Molecular Mechanisms of Hepatocellular Carcinoma: Insights to Therapy	p. 109
Genomic Profiling of Human Hepatocellular Carcinoma	p. 131
Pathologic Aspects of Hepatocellular Tumors	p. 183
Hepatocellular Carcinoma Associated with Hepatitis B Virus	p. 235
Hepatitis C and Hepatocellular Carcinoma	p. 259
Metabolic Disease and Hepatocellular Carcinoma	p. 283
Clinical Features and a Clinician's Diagnostic Approach to Hepatocellular Carcinoma	p. 309
Screening and Biomarkers for Hepatocellular Carcinoma	p. 327
Use of Imaging Techniques to Screen for Hepatocellular Carcinoma	p. 349
MRI for Detection and Evaluation of Hepatocellular Carcinoma	p. 369
Ultrasound of Hepatocellular Carcinoma: The Important Contribution of Contrast Enhancement	p. 387
Percutaneous Ethanol Injection	p. 407
Radiofrequency Ablation of Hepatocellular Carcinoma	p. 421
Resection of Hepatocellular Carcinoma	p. 453
Liver Transplantation for Hepatocellular Carcinoma	p. 467
Living Donor Liver Transplantation for Hepatocellular Carcinoma	p. 491
Medical Therapy of HCC	p. 527
Percutaneous Interventional Technique for Intra-arterial Chemoembolization	p. 569
Molecular Targeted Therapies for HCC	p. 589
Radiation Therapy for Hepatocellular Carcinoma	p. 615
Psychosocial Issues in Hepatocellular Carcinoma	p. 641
Putting It All Together	p. 713
Subject Index	p. 721
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