International Review of Cytology

by Jeon

• ISBN13: 9780123741790
• ISBN10: 0123741793
• Edition: 1st
• Format: Hardcover
• Copyright: 2007-08-24
• Publisher: Elsevier Science

Summary

International Review of Cytology presents current advances and comprehensive reviews in cell biology both plant and animal. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Articles in this volume include Mechanisms of Gradient Detection: A Comparison of Axon Pathfinding with Eukaryotic Cell Migration; Leptin and the Regulation of Hypothalamic-Pituitary-Adrenal Axis; Focal Adhesion and p53 Signaling in Cancer Cells; Cell and Molecular Biology of the Spindle Matrix; Mitochondrial Biology and Disease in Dictyostelium; Oxytocin and the Human Prostate in Health and Disease.

Table of Contents

Contributors	p. vii
Mechanisms of Gradient Detection: A Comparison of Axon Pathfinding with Eukaryotic Cell Migration	p. 1
Introduction	p. 2
Mechanisms of Gradient Detection in Selected Eukaryotic Cell Types	p. 4
Common Grounds and Diversity	p. 41
Concluding Remarks	p. 51
Acknowledgments	p. 52
References	p. 52
Leptin and the Regulation of the Hypothalamic-Pituitary-Adrenal Axis	p. 63
Introduction	p. 64
Biology of Leptin and Its Receptors	p. 65
Expression of Leptin and Its Receptors in the Hypothalamic-Pituitary-Adrenal Axis	p. 69
Effects of Leptin on the Central Branch of the Hypothalamic-Pituitary-Adrenal Axis	p. 76
Effects of Leptin on the Peripheral Branch of the Hypothalamic-Pituitary-Adrenal Axis	p. 78
Involvement of Leptin in the Pathophysiology of the Hypothalamic-Pituitary-Adrenal Axis	p. 85
Concluding Remarks	p. 88
Acknowledgments	p. 89
References	p. 89
Focal Adhesion Kinase and p53 Signaling in Cancer Cells	p. 103
Introduction	p. 104
Structure and Function of Focal Adhesion Kinase Protein	p. 105
FAK in Tumorigenesis	p. 122
FAK and p53 Association	p. 129
FAK and p53 Targeted Therapy	p. 136
Summary	p. 138
Acknowledgments	p. 138
References	p. 138
Cell and Molecular Biology of the Spindle Matrix	p. 155
Introduction	p. 156
Microtubule Spindle Dynamics and Force Production	p. 157
Evidence for a Spindle Matrix	p. 161
Concluding Remarks	p. 188
Acknowledgments	p. 190
References	p. 190
Mitochondrial Biology and Disease in Dictyostelium	p. 207
Introduction	p. 208
Mitochondrial Biology	p. 209
Mitochondrial Disease	p. 223
Concluding Remarks	p. 242
References	p. 243
Oxytocin and the Human Prostate in Health and Disease	p. 253
Introduction	p. 254
The Human Prostate	p. 254
Oxytocin and Oxytocin Receptor	p. 259
Oxytocin and the Prostate	p. 264
Possible Roles of Oxytocin in the Pathophysiology of Prostate Disease	p. 274
Concluding Remarks	p. 278
References	p. 278
Index	p. 287
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