Lecture Notes Clinical Biochemistry, 7th Edition

by G. J. Beckett (University of Edinburgh); Simon W. Walker (Edinburgh Royal Infirmary, Edinburgh); Peter Rae (Western General Hospital); Peter Ashby (Western General Hospital, Edinburgh)

• ISBN13: 9781405129596
• ISBN10: 140512959X
• Edition: 7th
• Format: Paperback
• Copyright: 2005-11-01
• Publisher: Wiley-Blackwell

Summary

Lecture Notes: Clinical Biochemistry presents the fundamental science underpinning common chemical investigations used in clinical practice. It takes a practically relevant approach that enables medical students and junior doctors to:Understand the value and limitations of chemical investigations Develop the skill to select appropriate investigations for diagnosis and management Interpret investigations correctly Develop a critical approach to diagnostic investigationsLecture Notes: Clinical Biochemistry takes a system-based approach. The underlying physiological rationale for any test is explained in the context of disruption by disease. This leads naturally to an integrated and practical understanding of chemical diagnostics.Case studies at the end of each chapter provide a clinical setting to help develop test-selection skills.Lecture Notes: Clinical Biochemistry provides the essential background to chemical investigations for medical students, junior doctors on foundation programmes, and nurses and practitioners involved in requesting or providing diagnostic service.

Author Biography

Dr Geoff Beckett, Reader in Clinical Biochemistry at the University of Edinburgh

Dr Simon Walker, Senior Lecturer in Clinical Biochemistry at the University of Edinburgh

Dr Peter Rae, Consultant Clinical Biochemist, Western General Hospital, Edinburgh

Dr Peter Ashby, Clinical Biochemist, Western General Hospital, Edinburgh

Table of Contents

Preface	vi
List of abbreviations	vii
Requesting and interpreting tests	1	(17)
Disturbances of water, sodium and potassium balance	18	(20)
Acid-base balance and oxygen transport	38	(15)
Renal disease	53	(19)
Disorders of calcium, phosphate and magnesium metabolism	72	(20)
Trauma, inflammation, immunity and malignancy	92	(15)
Liver disease	107	(14)
Gastrointestinal tract disease	121	(11)
Nutrition	132	(15)
Diabetes mellitus and hypoglycaemia	147	(13)
Cardiovascular disorders	160	(17)
Disorders of iron and porphyrin metabolism	177	(12)
Uric acid, gout and purine metabolism	189	(7)
Disorders of the hypothalamus and pituitary	196	(11)
Abnormalities of thyroid function	207	(14)
Disorders of the adrenal cortex and medulla	221	(19)
Investigation of gonadal function, infertility, menstrual irregularities and hirsutism	240	(15)
Pregnancy and antenatal screening	255	(7)
Clinical biochemistry in paediatrics and geriatrics	262	(17)
Central nervous system and cerebrospinal fluid	279	(4)
Therapeutic drug monitoring and chemical toxicology	283	(12)
Appendix A Collection of specimens	295	(3)
Appendix B Point of care testing (POCT)	298	(4)
Appendix C SI units and `conventional' units	302	(3)
Index	305